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Locally Advanced Small Intestinal Adenocarcinoma

MedGen UID:
1786491
•Concept ID:
C5446588
•
Neoplastic Process

Definition

Small intestinal adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Small Intestinal Adenocarcinoma

Professional guidelines

PubMed

Small Bowel Adenocarcinoma: From Molecular Insights to Clinical Management.
Gelsomino F, Balsano R, De Lorenzo S, Garajová I
Curr Oncol 2022 Feb 17;29(2):1223-1236. doi: 10.3390/curroncol29020104. PMID: 35200603Free PMC Article
The evolving management of small bowel adenocarcinoma.
de Bree E, Rovers KP, Stamatiou D, Souglakos J, Michelakis D, de Hingh IH
Acta Oncol 2018 Jun;57(6):712-722. Epub 2018 Jan 30 doi: 10.1080/0284186X.2018.1433321. PMID: 29381126
Management of small bowel adenocarcinoma.
Kummar S, Ciesielski TE, Fogarasi MC
Oncology (Williston Park) 2002 Oct;16(10):1364-9; discussion 1370, 1372-3. PMID: 12435206

Recent clinical studies

Etiology

Natural history and prognostic factors for localised small bowel adenocarcinoma.
Colina A, Hwang H, Wang H, Katz MHG, Sun R, Lee JE, Thomas J, Tzeng CW, Wolff RA, Raghav K, Overman MJ
ESMO Open 2020 Nov;5(6):e000960. doi: 10.1136/esmoopen-2020-000960. PMID: 33188051Free PMC Article
Prognostic factors of non-ampullary duodenal adenocarcinoma.
Hirashita T, Ohta M, Tada K, Saga K, Takayama H, Endo Y, Uchida H, Iwashita Y, Inomata M
Jpn J Clin Oncol 2018 Aug 1;48(8):743-747. doi: 10.1093/jjco/hyy086. PMID: 29931295
Laparoscopic Pelvic Exenteration for Locally Advanced Rectal Cancer, Technique and Short-Term Outcomes.
Pokharkar A, Kammar P, D'souza A, Bhamre R, Sugoor P, Saklani A
J Laparoendosc Adv Surg Tech A 2018 Dec;28(12):1489-1494. Epub 2018 May 9 doi: 10.1089/lap.2018.0147. PMID: 29741977
Rectal carcinoids: a systematic review.
McDermott FD, Heeney A, Courtney D, Mohan H, Winter D
Surg Endosc 2014 Jul;28(7):2020-6. Epub 2014 Mar 1 doi: 10.1007/s00464-014-3430-0. PMID: 24584484
Surgery for midgut carcinoid.
Sutton R, Doran HE, Williams EM, Vora J, Vinjamuri S, Evans J, Campbell F, Raraty MG, Ghaneh P, Hartley M, Poston GJ, Neoptolemos JP
Endocr Relat Cancer 2003 Dec;10(4):469-81. doi: 10.1677/erc.0.0100469. PMID: 14713260

Diagnosis

Natural history and prognostic factors for localised small bowel adenocarcinoma.
Colina A, Hwang H, Wang H, Katz MHG, Sun R, Lee JE, Thomas J, Tzeng CW, Wolff RA, Raghav K, Overman MJ
ESMO Open 2020 Nov;5(6):e000960. doi: 10.1136/esmoopen-2020-000960. PMID: 33188051Free PMC Article
Surgical Principles in the Management of Small Bowel Neuroendocrine Tumors.
Gangi A, Anaya DA
Curr Treat Options Oncol 2020 Aug 29;21(11):88. doi: 10.1007/s11864-020-00784-2. PMID: 32862334
The evolving management of small bowel adenocarcinoma.
de Bree E, Rovers KP, Stamatiou D, Souglakos J, Michelakis D, de Hingh IH
Acta Oncol 2018 Jun;57(6):712-722. Epub 2018 Jan 30 doi: 10.1080/0284186X.2018.1433321. PMID: 29381126
Rectal carcinoids: a systematic review.
McDermott FD, Heeney A, Courtney D, Mohan H, Winter D
Surg Endosc 2014 Jul;28(7):2020-6. Epub 2014 Mar 1 doi: 10.1007/s00464-014-3430-0. PMID: 24584484
Tumors of the ampulla of Vater.
Jean M, Dua K
Curr Gastroenterol Rep 2003 Apr;5(2):171-5. doi: 10.1007/s11894-003-0088-5. PMID: 12631460

Therapy

Progress in the Treatment of Small Intestine Cancer.
Symons R, Daly D, Gandy R, Goldstein D, Aghmesheh M
Curr Treat Options Oncol 2023 Apr;24(4):241-261. Epub 2023 Feb 24 doi: 10.1007/s11864-023-01058-3. PMID: 36826686
Surgical Principles in the Management of Small Bowel Neuroendocrine Tumors.
Gangi A, Anaya DA
Curr Treat Options Oncol 2020 Aug 29;21(11):88. doi: 10.1007/s11864-020-00784-2. PMID: 32862334
ALK inhibitors in the treatment of advanced NSCLC.
Gridelli C, Peters S, Sgambato A, Casaluce F, Adjei AA, Ciardiello F
Cancer Treat Rev 2014 Mar;40(2):300-6. Epub 2013 Aug 7 doi: 10.1016/j.ctrv.2013.07.002. PMID: 23931927
Gastrointestinal carcinoid tumors: diagnosis and treatment.
Stamatakos M, Kontzoglou K, Sargedi C, Tsaknaki S, Iannescu R, Safioleas C, Kaitanidi V, Safioleas M
Chirurgia (Bucur) 2010 Nov-Dec;105(6):759-66. PMID: 21351698
Management of small bowel adenocarcinoma.
Kummar S, Ciesielski TE, Fogarasi MC
Oncology (Williston Park) 2002 Oct;16(10):1364-9; discussion 1370, 1372-3. PMID: 12435206

Prognosis

Small Bowel Adenocarcinoma: From Molecular Insights to Clinical Management.
Gelsomino F, Balsano R, De Lorenzo S, Garajová I
Curr Oncol 2022 Feb 17;29(2):1223-1236. doi: 10.3390/curroncol29020104. PMID: 35200603Free PMC Article
Natural history and prognostic factors for localised small bowel adenocarcinoma.
Colina A, Hwang H, Wang H, Katz MHG, Sun R, Lee JE, Thomas J, Tzeng CW, Wolff RA, Raghav K, Overman MJ
ESMO Open 2020 Nov;5(6):e000960. doi: 10.1136/esmoopen-2020-000960. PMID: 33188051Free PMC Article
The evolving management of small bowel adenocarcinoma.
de Bree E, Rovers KP, Stamatiou D, Souglakos J, Michelakis D, de Hingh IH
Acta Oncol 2018 Jun;57(6):712-722. Epub 2018 Jan 30 doi: 10.1080/0284186X.2018.1433321. PMID: 29381126
Periampullary carcinomas.
Filiz G, Yerci O, Adim SB, Gurel S, Dolar E, Memik F
Hepatogastroenterology 2007 Jun;54(76):1247-9. PMID: 17629080
Surgery for midgut carcinoid.
Sutton R, Doran HE, Williams EM, Vora J, Vinjamuri S, Evans J, Campbell F, Raraty MG, Ghaneh P, Hartley M, Poston GJ, Neoptolemos JP
Endocr Relat Cancer 2003 Dec;10(4):469-81. doi: 10.1677/erc.0.0100469. PMID: 14713260

Clinical prediction guides

Natural history and prognostic factors for localised small bowel adenocarcinoma.
Colina A, Hwang H, Wang H, Katz MHG, Sun R, Lee JE, Thomas J, Tzeng CW, Wolff RA, Raghav K, Overman MJ
ESMO Open 2020 Nov;5(6):e000960. doi: 10.1136/esmoopen-2020-000960. PMID: 33188051Free PMC Article
The characteristics and outcomes of small bowel adenocarcinoma: a multicentre retrospective observational study.
Sakae H, Kanzaki H, Nasu J, Akimoto Y, Matsueda K, Yoshioka M, Nakagawa M, Hori S, Inoue M, Inaba T, Imagawa A, Takatani M, Takenaka R, Suzuki S, Fujiwara T, Okada H
Br J Cancer 2017 Nov 21;117(11):1607-1613. Epub 2017 Oct 5 doi: 10.1038/bjc.2017.338. PMID: 28982111Free PMC Article
En Bloc Pancreaticoduodenectomy for Locally Advanced Right Colon Cancers.
Ağalar C, Canda AE, Unek T, Sokmen S
Int J Surg Oncol 2017;2017:5179686. Epub 2017 Jul 2 doi: 10.1155/2017/5179686. PMID: 28751989Free PMC Article
Characteristics and Treatment Strategies for Small Bowel Adenocarcinoma in Advanced-stage Cases.
Nakanoko T, Koga T, Taketani K, Hirayama Y, Yoshiya S, Minagawa R, Kai M, Kajiyama K, Maehara Y
Anticancer Res 2015 Jul;35(7):4135-8. PMID: 26124367
Periampullary carcinomas.
Filiz G, Yerci O, Adim SB, Gurel S, Dolar E, Memik F
Hepatogastroenterology 2007 Jun;54(76):1247-9. PMID: 17629080

Recent systematic reviews

Management and outcomes of mixed adenoneuroendocrine carcinoma of the ampulla of Vater: A systematic review and pooled analysis of 56 patients.
Ziogas IA, Rallis KS, Tasoudis PT, Moris D, Schulick RD, Del Chiaro M
Eur J Surg Oncol 2023 Apr;49(4):682-687. Epub 2023 Jan 9 doi: 10.1016/j.ejso.2023.01.005. PMID: 36646615
Adjuvant therapy for true ampullary cancer: a systematic review.
Bonet M, Rodrigo A, Vázquez S, Carrizo V, Vilardell F, Mira M
Clin Transl Oncol 2020 Aug;22(8):1407-1413. Epub 2020 Jan 11 doi: 10.1007/s12094-019-02278-6. PMID: 31927720
Gemcitabine-based chemotherapy for advanced biliary tract carcinomas.
Abdel-Rahman O, Elsayed Z, Elhalawani H
Cochrane Database Syst Rev 2018 Apr 6;4(4):CD011746. doi: 10.1002/14651858.CD011746.pub2. PMID: 29624208Free PMC Article
Rectal carcinoids: a systematic review.
McDermott FD, Heeney A, Courtney D, Mohan H, Winter D
Surg Endosc 2014 Jul;28(7):2020-6. Epub 2014 Mar 1 doi: 10.1007/s00464-014-3430-0. PMID: 24584484

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