U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Eye lymphoma

MedGen UID:
1788822
•Concept ID:
C0730306
•
Neoplastic Process
Synonyms: Eye Lymphoma; eye lymphoma; eyeball of camera-type eye lymphoma; lymphoma of eyeball of camera-type eye; Ocular Lymphoma; Primary Eye Lymphoma; primary eye lymphoma; Primary Ocular Lymphoma
 
Monarch Initiative: MONDO:0004034

Definition

A lymphoma that arises from the eye. [from NCI]

Professional guidelines

PubMed

International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors.
Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN
Int Forum Allergy Rhinol 2024 Feb;14(2):149-608. Epub 2024 Jan 2 doi: 10.1002/alr.23262. PMID: 37658764
Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Modern radiation therapy for extranodal lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group.
Yahalom J, Illidge T, Specht L, Hoppe RT, Li YX, Tsang R, Wirth A; International Lymphoma Radiation Oncology Group
Int J Radiat Oncol Biol Phys 2015 May 1;92(1):11-31. doi: 10.1016/j.ijrobp.2015.01.009. PMID: 25863750

Recent clinical studies

Etiology

Diagnosis and management of vitreoretinal lymphoma: present and future treatment perspectives.
Kaburaki T, Taoka K
Jpn J Ophthalmol 2023 Jul;67(4):363-381. Epub 2023 May 20 doi: 10.1007/s10384-023-00997-6. PMID: 37209195
Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Consensus Recommendations for the Diagnosis of Vitreoretinal Lymphoma.
Carbonell D, Mahajan S, Chee SP, Sobolewska B, Agrawal R, Bülow T, Gupta V, Jones NP, Accorinti M, Agarwal M, Batchelor T, Biswas J, Cimino L, tenDam-van Loon NH, de-la-Torre A, Frenkel S, Pe'er J, Kramer M, Miserocchi E, Mochizuki M, Ness T, Rosenbaum JT, Sen HN, Simion M (VRL patient), Sitter H, Vasconcelos-Santos DV, Habot-Wilner Z, Coupland SE, Pulido JS, Smith J, Thorne JE, Zierhut M; Study Group for Vitreoretinal Lymphoma Diagnostics
Ocul Immunol Inflamm 2021 Apr 3;29(3):507-520. Epub 2021 May 19 doi: 10.1080/09273948.2021.1878233. PMID: 34009095
Orbital AL amyloid.
Chan TM, Prospero Ponce CM, Allen RC, Bell D, Lee AG
Orbit 2020 Feb;39(1):68-70. Epub 2019 Apr 25 doi: 10.1080/01676830.2019.1594980. PMID: 31020884
Modern radiation therapy for extranodal lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group.
Yahalom J, Illidge T, Specht L, Hoppe RT, Li YX, Tsang R, Wirth A; International Lymphoma Radiation Oncology Group
Int J Radiat Oncol Biol Phys 2015 May 1;92(1):11-31. doi: 10.1016/j.ijrobp.2015.01.009. PMID: 25863750

Diagnosis

Diagnosis and management of vitreoretinal lymphoma: present and future treatment perspectives.
Kaburaki T, Taoka K
Jpn J Ophthalmol 2023 Jul;67(4):363-381. Epub 2023 May 20 doi: 10.1007/s10384-023-00997-6. PMID: 37209195
Conjunctival Lymphoma.
McGrath LA, Ryan DA, Warrier SK, Coupland SE, Glasson WJ
Eye (Lond) 2023 Apr;37(5):837-848. Epub 2022 Jul 26 doi: 10.1038/s41433-022-02176-2. PMID: 35882984Free PMC Article
Intraocular Lymphoma.
Cunningham ET, Miserocchi E, Smith JR, Gonzales JA, Zierhut M
Ocul Immunol Inflamm 2021 Apr 3;29(3):425-429. doi: 10.1080/09273948.2021.1941684. PMID: 34296968
Lymphoma of the eyelid.
Svendsen FH, Heegaard S
Surv Ophthalmol 2017 May-Jun;62(3):312-331. Epub 2016 Nov 26 doi: 10.1016/j.survophthal.2016.11.009. PMID: 27894880
Primary vitreoretinal lymphoma.
Mulay K, Narula R, Honavar SG
Indian J Ophthalmol 2015 Mar;63(3):180-6. doi: 10.4103/0301-4738.156903. PMID: 25971162Free PMC Article

Therapy

Diagnostic methods for primary vitreoretinal lymphoma: A systematic review.
Huang RS, Mihalache A, Popovic MM, Cruz-Pimentel M, Pandya BU, Muni RH, Kertes PJ
Surv Ophthalmol 2024 May-Jun;69(3):456-464. Epub 2023 Dec 30 doi: 10.1016/j.survophthal.2023.12.001. PMID: 38163550
Diagnosis and management of vitreoretinal lymphoma: present and future treatment perspectives.
Kaburaki T, Taoka K
Jpn J Ophthalmol 2023 Jul;67(4):363-381. Epub 2023 May 20 doi: 10.1007/s10384-023-00997-6. PMID: 37209195
Conjunctival Lymphoma.
McGrath LA, Ryan DA, Warrier SK, Coupland SE, Glasson WJ
Eye (Lond) 2023 Apr;37(5):837-848. Epub 2022 Jul 26 doi: 10.1038/s41433-022-02176-2. PMID: 35882984Free PMC Article
Evidence-based expert consensus on the management of primary central nervous system lymphoma in China.
Chen T, Liu Y, Wang Y, Chang Q, Wu J, Wang Z, Geng D, Yu JT, Li Y, Li XQ, Chen H, Zhuang D, Li J, Wang B, Jiang T, Lyu L, Song Y, Qiu X, Li W, Lin S, Zhang X, Lu D, Lei J, Chen Y, Mao Y
J Hematol Oncol 2022 Sep 29;15(1):136. doi: 10.1186/s13045-022-01356-7. PMID: 36176002Free PMC Article
Primary intraocular lymphoma.
Sagoo MS, Mehta H, Swampillai AJ, Cohen VM, Amin SZ, Plowman PN, Lightman S
Surv Ophthalmol 2014 Sep-Oct;59(5):503-16. Epub 2013 Dec 31 doi: 10.1016/j.survophthal.2013.12.001. PMID: 24560125

Prognosis

Diagnostic methods for primary vitreoretinal lymphoma: A systematic review.
Huang RS, Mihalache A, Popovic MM, Cruz-Pimentel M, Pandya BU, Muni RH, Kertes PJ
Surv Ophthalmol 2024 May-Jun;69(3):456-464. Epub 2023 Dec 30 doi: 10.1016/j.survophthal.2023.12.001. PMID: 38163550
Conjunctival Lymphoma.
McGrath LA, Ryan DA, Warrier SK, Coupland SE, Glasson WJ
Eye (Lond) 2023 Apr;37(5):837-848. Epub 2022 Jul 26 doi: 10.1038/s41433-022-02176-2. PMID: 35882984Free PMC Article
Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Lymphoma of the eyelid.
Svendsen FH, Heegaard S
Surv Ophthalmol 2017 May-Jun;62(3):312-331. Epub 2016 Nov 26 doi: 10.1016/j.survophthal.2016.11.009. PMID: 27894880
Neoplastic masquerade syndromes.
Read RW, Zamir E, Rao NA
Surv Ophthalmol 2002 Mar-Apr;47(2):81-124. doi: 10.1016/s0039-6257(01)00305-8. PMID: 11918892

Clinical prediction guides

Global fertility in 204 countries and territories, 1950-2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Fertility and Forecasting Collaborators
Lancet 2024 May 18;403(10440):2057-2099. Epub 2024 Mar 20 doi: 10.1016/S0140-6736(24)00550-6. PMID: 38521087Free PMC Article
Conjunctival Lymphoma.
McGrath LA, Ryan DA, Warrier SK, Coupland SE, Glasson WJ
Eye (Lond) 2023 Apr;37(5):837-848. Epub 2022 Jul 26 doi: 10.1038/s41433-022-02176-2. PMID: 35882984Free PMC Article
Ocular adnexal lymphoma: Subtype-specific clinical and genetic features.
Kirkegaard MK
Acta Ophthalmol 2022 Oct;100 Suppl 270:3-37. doi: 10.1111/aos.15248. PMID: 36196757
Natural and iatrogenic ocular manifestations of rheumatoid arthritis: a systematic review.
Dammacco R, Guerriero S, Alessio G, Dammacco F
Int Ophthalmol 2022 Feb;42(2):689-711. Epub 2021 Nov 21 doi: 10.1007/s10792-021-02058-8. PMID: 34802085Free PMC Article
Neuro-Ophthalmic Manifestations of Intracranial Malignancies.
Dermarkarian CR, Kini AT, Al Othman BA, Lee AG
J Neuroophthalmol 2020 Sep;40(3):e31-e48. doi: 10.1097/WNO.0000000000000950. PMID: 32282510

Recent systematic reviews

Diagnostic methods for primary vitreoretinal lymphoma: A systematic review.
Huang RS, Mihalache A, Popovic MM, Cruz-Pimentel M, Pandya BU, Muni RH, Kertes PJ
Surv Ophthalmol 2024 May-Jun;69(3):456-464. Epub 2023 Dec 30 doi: 10.1016/j.survophthal.2023.12.001. PMID: 38163550
Comparison of blinatumomab and CAR T-cell therapy in relapsed/refractory acute lymphoblastic leukemia: a systematic review and meta-analysis.
Zhai Y, Hong J, Wang J, Jiang Y, Wu W, Lv Y, Guo J, Tian L, Sun H, Li Y, Li C, Zhan H, Zhao Z
Expert Rev Hematol 2024 Jan-Mar;17(1-3):67-76. Epub 2024 Jan 4 doi: 10.1080/17474086.2023.2298732. PMID: 38135295
Efficacy and safety of first-line combination therapy versus monotherapy for vitreoretinal lymphoma: a systematic review and meta-analysis.
Gao J, Peng X, Wang L
BMC Ophthalmol 2023 Nov 22;23(1):477. doi: 10.1186/s12886-023-03226-3. PMID: 37993841Free PMC Article
Natural and iatrogenic ocular manifestations of rheumatoid arthritis: a systematic review.
Dammacco R, Guerriero S, Alessio G, Dammacco F
Int Ophthalmol 2022 Feb;42(2):689-711. Epub 2021 Nov 21 doi: 10.1007/s10792-021-02058-8. PMID: 34802085Free PMC Article
Ophthalmic involvement of chronic lymphocytic leukemia: A systematic review of 123 cases.
Delestre F, Blanche P, Bouayed E, Bouscary D, Mouthon L, Brezin A, Le Jeunne C, Chaigne B
Surv Ophthalmol 2021 Jan-Feb;66(1):124-131. Epub 2020 May 11 doi: 10.1016/j.survophthal.2020.05.001. PMID: 32407752

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...