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Locally Advanced Thyroid Gland Oncocytic Carcinoma

MedGen UID:
1789114
•Concept ID:
C5446582
•
Neoplastic Process
Synonyms: Locally Advanced Thyroid Gland Hurthle Cell Carcinoma; Locally Advanced Thyroid Gland Oncocytic (Hurthle Cell) Carcinoma

Definition

Thyroid gland oncocytic carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Thyroid Gland Oncocytic Carcinoma

Professional guidelines

PubMed

Advances in the management of MEN2: from improved surgical and medical treatment to novel kinase inhibitors.
Wells SA Jr
Endocr Relat Cancer 2018 Feb;25(2):T1-T13. Epub 2017 Nov 15 doi: 10.1530/ERC-17-0325. PMID: 29142004Free PMC Article
Sialoendoscopy: a viable treatment for I(131) induced sialoadenitis.
De Luca R, Vicidomini A, Trodella M, Tartaro G, Colella G
Br J Oral Maxillofac Surg 2014 Sep;52(7):641-6. Epub 2014 Jun 2 doi: 10.1016/j.bjoms.2014.01.025. PMID: 24894709
Genetics, diagnosis, and management of medullary thyroid carcinoma and pheochromocytoma/paraganglioma.
Moraitis AG, Martucci VL, Pacak K
Endocr Pract 2014 Feb;20(2):176-87. doi: 10.4158/EP13268.RA. PMID: 24449662

Recent clinical studies

Etiology

Papillary thyroid carcinoma arising in ectopic thyroid tissue within sternocleidomastoid muscle: a review of current literature.
Barrea L, Fonderico F, DI Somma C, Pugliese G, DE Alteriis G, Mascolo M, Colao A, Savastano S
Minerva Endocrinol 2020 Dec;45(4):318-325. Epub 2020 Aug 3 doi: 10.23736/S0391-1977.20.03167-3. PMID: 32744438
Cabozantinib and vandetanib for unresectable locally advanced or metastatic medullary thyroid cancer: a systematic review and economic model.
Tappenden P, Carroll C, Hamilton J, Kaltenthaler E, Wong R, Wadsley J, Moss L, Balasubramanian S
Health Technol Assess 2019 Feb;23(8):1-144. doi: 10.3310/hta23080. PMID: 30821231Free PMC Article
Advances in the management of MEN2: from improved surgical and medical treatment to novel kinase inhibitors.
Wells SA Jr
Endocr Relat Cancer 2018 Feb;25(2):T1-T13. Epub 2017 Nov 15 doi: 10.1530/ERC-17-0325. PMID: 29142004Free PMC Article
Genetics, diagnosis, and management of medullary thyroid carcinoma and pheochromocytoma/paraganglioma.
Moraitis AG, Martucci VL, Pacak K
Endocr Pract 2014 Feb;20(2):176-87. doi: 10.4158/EP13268.RA. PMID: 24449662
Update on the cytologic and molecular features of medullary thyroid carcinoma.
Pusztaszeri MP, Bongiovanni M, Faquin WC
Adv Anat Pathol 2014 Jan;21(1):26-35. doi: 10.1097/PAP.0000000000000004. PMID: 24316908

Diagnosis

How I treat medullary thyroid cancer.
Kiesewetter B, Riss P, Scheuba C, Raderer M
ESMO Open 2021 Jun;6(3):100183. Epub 2021 Jun 3 doi: 10.1016/j.esmoop.2021.100183. PMID: 34091261Free PMC Article
Synchronous intrathyroidal parathyroid carcinoma and thyroid carcinoma: case report and review of the literature.
De Falco N, Santangelo G, Chirico F, Cangiano A, Sommella MG, Cosenza A, Ronchi A, Accardo M, Pellino G, Parmeggiani D, Canonico S, De Falco M
BMC Endocr Disord 2021 Apr 7;21(1):60. doi: 10.1186/s12902-021-00724-7. PMID: 33827539Free PMC Article
Papillary thyroid carcinoma arising in ectopic thyroid tissue within sternocleidomastoid muscle: a review of current literature.
Barrea L, Fonderico F, DI Somma C, Pugliese G, DE Alteriis G, Mascolo M, Colao A, Savastano S
Minerva Endocrinol 2020 Dec;45(4):318-325. Epub 2020 Aug 3 doi: 10.23736/S0391-1977.20.03167-3. PMID: 32744438
Genetics, diagnosis, and management of medullary thyroid carcinoma and pheochromocytoma/paraganglioma.
Moraitis AG, Martucci VL, Pacak K
Endocr Pract 2014 Feb;20(2):176-87. doi: 10.4158/EP13268.RA. PMID: 24449662
Update on the cytologic and molecular features of medullary thyroid carcinoma.
Pusztaszeri MP, Bongiovanni M, Faquin WC
Adv Anat Pathol 2014 Jan;21(1):26-35. doi: 10.1097/PAP.0000000000000004. PMID: 24316908

Therapy

Synchronous intrathyroidal parathyroid carcinoma and thyroid carcinoma: case report and review of the literature.
De Falco N, Santangelo G, Chirico F, Cangiano A, Sommella MG, Cosenza A, Ronchi A, Accardo M, Pellino G, Parmeggiani D, Canonico S, De Falco M
BMC Endocr Disord 2021 Apr 7;21(1):60. doi: 10.1186/s12902-021-00724-7. PMID: 33827539Free PMC Article
Rare location of head and neck adenoid cystic carcinoma.
Naim A, Hajjij A, Abbad F, Rami A, Essaadi M
Pan Afr Med J 2019;34:33. Epub 2019 Sep 16 doi: 10.11604/pamj.2019.34.33.19245. PMID: 31762901Free PMC Article
Cabozantinib and vandetanib for unresectable locally advanced or metastatic medullary thyroid cancer: a systematic review and economic model.
Tappenden P, Carroll C, Hamilton J, Kaltenthaler E, Wong R, Wadsley J, Moss L, Balasubramanian S
Health Technol Assess 2019 Feb;23(8):1-144. doi: 10.3310/hta23080. PMID: 30821231Free PMC Article
Advances in the management of MEN2: from improved surgical and medical treatment to novel kinase inhibitors.
Wells SA Jr
Endocr Relat Cancer 2018 Feb;25(2):T1-T13. Epub 2017 Nov 15 doi: 10.1530/ERC-17-0325. PMID: 29142004Free PMC Article
Sorafenib in Japanese Patients with Locally Advanced or Metastatic Medullary Thyroid Carcinoma and Anaplastic Thyroid Carcinoma.
Ito Y, Onoda N, Ito KI, Sugitani I, Takahashi S, Yamaguchi I, Kabu K, Tsukada K
Thyroid 2017 Sep;27(9):1142-1148. Epub 2017 Jul 24 doi: 10.1089/thy.2016.0621. PMID: 28635560Free PMC Article

Prognosis

Solid variant of papillary thyroid carcinoma: An analysis of 28 cases with current literature.
Vural Ç, Kiraz U, Turan G, Özkara SK, Sözen M, Çetinarslan B
Ann Diagn Pathol 2021 Jun;52:151737. Epub 2021 Mar 31 doi: 10.1016/j.anndiagpath.2021.151737. PMID: 33838489
Giant nonfunctioning adrenal tumors: two case reports and review of the literature.
Chatzoulis G, Passos I, Bakaloudi DR, Giannakidis D, Koumpoulas A, Ioannidis K, Tsifountoudis I, Pappas D, Spyridopoulos P
J Med Case Rep 2018 Nov 10;12(1):335. doi: 10.1186/s13256-018-1876-8. PMID: 30413177Free PMC Article
Recurrence pattern after conservative surgery for papillary thyroid carcinoma.
Kobayashi K, Takenouchi S, Mitani H, Yoshida T
Auris Nasus Larynx 2014 Dec;41(6):548-51. Epub 2014 Jun 26 doi: 10.1016/j.anl.2014.05.012. PMID: 24976169
Sialoendoscopy: a viable treatment for I(131) induced sialoadenitis.
De Luca R, Vicidomini A, Trodella M, Tartaro G, Colella G
Br J Oral Maxillofac Surg 2014 Sep;52(7):641-6. Epub 2014 Jun 2 doi: 10.1016/j.bjoms.2014.01.025. PMID: 24894709
Prognostic and predictive markers in medullary thyroid carcinoma.
Erovic BM, Kim D, Cassol C, Goldstein DP, Irish JC, Asa SL, Mete O
Endocr Pathol 2012 Dec;23(4):232-42. doi: 10.1007/s12022-012-9225-8. PMID: 23150029

Clinical prediction guides

Solid variant of papillary thyroid carcinoma: An analysis of 28 cases with current literature.
Vural Ç, Kiraz U, Turan G, Özkara SK, Sözen M, Çetinarslan B
Ann Diagn Pathol 2021 Jun;52:151737. Epub 2021 Mar 31 doi: 10.1016/j.anndiagpath.2021.151737. PMID: 33838489
Postoperative Surveillance in Older Adults With T1N0M0 Low-risk Papillary Thyroid Cancer.
Pradhan MC, Kazaure HS, Wang F, Zambeli-Ljepovic A, Perkins JM, Stang MT, Scheri RP
J Surg Res 2021 Aug;264:37-44. Epub 2021 Mar 22 doi: 10.1016/j.jss.2021.01.049. PMID: 33765509
A novel thyroid function index associated with opposite therapeutic outcomes in advanced hepatocellular carcinoma patients receiving chemotherapy or sorafenib.
Chu YD, Lin KH, Huang YH, Lin CC, Hung CF, Yeh TS, Lee WC, Yeh CT
Asia Pac J Clin Oncol 2018 Oct;14(5):e341-e351. Epub 2018 May 21 doi: 10.1111/ajco.12983. PMID: 29785761
Prognostic and predictive markers in medullary thyroid carcinoma.
Erovic BM, Kim D, Cassol C, Goldstein DP, Irish JC, Asa SL, Mete O
Endocr Pathol 2012 Dec;23(4):232-42. doi: 10.1007/s12022-012-9225-8. PMID: 23150029
Fibrillin expression and localization in various types of carcinomas of the thyroid gland.
Tseleni-Balafouta S, Gakiopoulou H, Fanourakis G, Voutsinas G, Litsiou H, Sozopoulos E, Balafoutas D, Patsouris E
Mod Pathol 2006 May;19(5):695-700. doi: 10.1038/modpathol.3800578. PMID: 16528372

Recent systematic reviews

Cabozantinib and vandetanib for unresectable locally advanced or metastatic medullary thyroid cancer: a systematic review and economic model.
Tappenden P, Carroll C, Hamilton J, Kaltenthaler E, Wong R, Wadsley J, Moss L, Balasubramanian S
Health Technol Assess 2019 Feb;23(8):1-144. doi: 10.3310/hta23080. PMID: 30821231Free PMC Article

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