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Small Intestinal Non-Hodgkin Lymphoma

MedGen UID:
233454
•Concept ID:
C1336006
•
Neoplastic Process
Synonyms: Primary Small Intestinal Non-Hodgkin's Lymphoma; Small Intestinal Non-Hodgkin's Lymphoma; Small Intestine Non-Hodgkin's Lymphoma

Definition

A B-cell or T-cell non-Hodgkin lymphoma that arises from the small intestine. Representative examples of B-cell non-Hodgkin lymphoma include diffuse large B-cell lymphoma, MALT lymphoma, alpha heavy chain disease/immunoproliferative small intestinal disease, Burkitt lymphoma, follicular lymphoma, and mantle cell lymphoma. The T-cell non-Hodgkin lymphomas are the enteropathy-associated T-cell lymphoma and the monomorphic CD56 positive intestinal T-cell lymphoma. [from NCI]

Professional guidelines

PubMed

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
AGA Clinical Practice Update on Management of Refractory Celiac Disease: Expert Review.
Green PHR, Paski S, Ko CW, Rubio-Tapia A
Gastroenterology 2022 Nov;163(5):1461-1469. Epub 2022 Sep 19 doi: 10.1053/j.gastro.2022.07.086. PMID: 36137844
Surgical Management of Small Bowel Lymphoma.
Lu PW, Fields AC, Yoo J, Irani J, Goldberg JE, Bleday R, Melnitchouk N
J Gastrointest Surg 2021 Mar;25(3):757-765. Epub 2020 Jul 14 doi: 10.1007/s11605-020-04730-3. PMID: 32666499

Recent clinical studies

Etiology

New developments in non-Hodgkin lymphoid malignancies.
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Rare T-Cell Subtypes.
van der Weyden C, McCormack C, Lade S, Johnstone RW, Prince HM
Cancer Treat Res 2019;176:195-224. doi: 10.1007/978-3-319-99716-2_10. PMID: 30596220
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Neutropenic enterocolitis.
Davila ML
Curr Opin Gastroenterol 2006 Jan;22(1):44-7. doi: 10.1097/01.mog.0000198073.14169.3b. PMID: 16319675

Diagnosis

New developments in non-Hodgkin lymphoid malignancies.
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Enteropathy-associated T-cell lymphoma.
Ferreri AJ, Zinzani PL, Govi S, Pileri SA
Crit Rev Oncol Hematol 2011 Jul;79(1):84-90. Epub 2010 Jul 23 doi: 10.1016/j.critrevonc.2010.06.006. PMID: 20655757
Neutropenic enterocolitis.
Davila ML
Curr Opin Gastroenterol 2006 Jan;22(1):44-7. doi: 10.1097/01.mog.0000198073.14169.3b. PMID: 16319675

Therapy

Idelalisib: a review of its use in chronic lymphocytic leukaemia and indolent non-Hodgkin's lymphoma.
Keating GM
Target Oncol 2015 Mar;10(1):141-51. Epub 2015 Feb 1 doi: 10.1007/s11523-015-0359-8. PMID: 25637459
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Celiac disease.
Green PH, Cellier C
N Engl J Med 2007 Oct 25;357(17):1731-43. doi: 10.1056/NEJMra071600. PMID: 17960014
Neutropenic enterocolitis.
Davila ML
Curr Opin Gastroenterol 2006 Jan;22(1):44-7. doi: 10.1097/01.mog.0000198073.14169.3b. PMID: 16319675
Gut lymphomas.
Zucca E, Cavalli F
Baillieres Clin Haematol 1996 Dec;9(4):727-41. doi: 10.1016/s0950-3536(96)80051-5. PMID: 9138615

Prognosis

AGA Clinical Practice Update on Management of Refractory Celiac Disease: Expert Review.
Green PHR, Paski S, Ko CW, Rubio-Tapia A
Gastroenterology 2022 Nov;163(5):1461-1469. Epub 2022 Sep 19 doi: 10.1053/j.gastro.2022.07.086. PMID: 36137844
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Enteropathy-associated T-cell lymphoma.
Ferreri AJ, Zinzani PL, Govi S, Pileri SA
Crit Rev Oncol Hematol 2011 Jul;79(1):84-90. Epub 2010 Jul 23 doi: 10.1016/j.critrevonc.2010.06.006. PMID: 20655757
Neutropenic enterocolitis.
Davila ML
Curr Opin Gastroenterol 2006 Jan;22(1):44-7. doi: 10.1097/01.mog.0000198073.14169.3b. PMID: 16319675

Clinical prediction guides

Small intestinal follicular lymphoma induced by methotrexate: a case report.
Osaki Y, Kawaratani H, Kachi H, Matsuura K, Tsuji Y, Ozutsumi T, Takagi H, Furukawa M, Sawada Y, Mitoro A, Yamao J, Yoshiji H
BMC Gastroenterol 2021 Jul 8;21(1):280. doi: 10.1186/s12876-021-01849-8. PMID: 34238226Free PMC Article
The role of "watch and wait" in intestinal follicular lymphoma in rituximab era.
Tari A, Asaoku H, Takata K, Fujimori S, Tanaka S, Fujihara M, Koga T, Yoshino T
Scand J Gastroenterol 2016 Mar;51(3):321-8. Epub 2015 Sep 18 doi: 10.3109/00365521.2015.1087589. PMID: 26382560
Multiple Intestinal Lymphoma.
Mastalier B, Deaconescu V, Elaiah W, Drăghici C, Popp C, Zurac S, Balea M, Tevet M, Botezatu C
Rom J Intern Med 2015 Jan-Mar;53(1):73-8. doi: 10.1515/rjim-2015-0010. PMID: 26076564
Small intestinal involvement by lymphoproliferative disorders post-renal transplantation: a report from the post-transplant lymphoproliferative disorder international survey.
Khedmat H, Taheri S
Saudi J Kidney Dis Transpl 2013 May;24(3):487-94. doi: 10.4103/1319-2442.111017. PMID: 23640619
Expression of PIK3CA and FOXP1 in gastric and intestinal non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue type.
Zhai L, Zhao Y, Ye S, Huang H, Tian Y, Wu Q, Lin H, Lin T
Tumour Biol 2011 Oct;32(5):913-20. Epub 2011 Jun 10 doi: 10.1007/s13277-011-0192-3. PMID: 21660567

Recent systematic reviews

Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Composite EBV negative peripheral T-cell lymphoma and diffuse large B-cell lymphoma involving the ileum: a case report and a systematic review of the literature.
Abou-Elella AA, Nifong TP
Leuk Lymphoma 2006 Oct;47(10):2208-17. doi: 10.1080/10428190600763348. PMID: 17071497

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