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Human Papillomavirus-Related Cervical Carcinoma

MedGen UID:
235177
•Concept ID:
C1334051
•
Neoplastic Process
Synonyms: HPV-Associated Cervical Carcinoma; HPV-Related Cervical Carcinoma; HPVA Cervical Carcinoma; Human Papilloma Virus Related Cervical Carcinoma; Human Papilloma Virus-Related Cervical Carcinoma; Human Papillomavirus-Associated Cervical Carcinoma

Definition

A carcinoma that arises from the cervix and is caused by human papillomavirus infection. [from NCI]

Professional guidelines

PubMed

De-Escalation Treatment for Human Papillomavirus-Related Oropharyngeal Cancer: Questions for Practical Consideration.
Chen AM
Oncology (Williston Park) 2023 Jul 21;37(7):281-287. doi: 10.46883/2023.25921000. PMID: 37499250
Transoral Robotic Surgery and De-escalation of Cancer Treatment.
Wahle B, Zevallos J
Otolaryngol Clin North Am 2020 Dec;53(6):981-994. Epub 2020 Sep 8 doi: 10.1016/j.otc.2020.07.009. PMID: 32917423Free PMC Article
Clinical management of emerging sinonasal malignancies.
Contrera KJ, Woody NM, Rahman M, Sindwani R, Burkey BB
Head Neck 2020 Aug;42(8):2202-2212. Epub 2020 Mar 25 doi: 10.1002/hed.26150. PMID: 32212360

Recent clinical studies

Etiology

Global epidemiologic patterns of oropharyngeal cancer incidence trends.
Zumsteg ZS, Luu M, Rosenberg PS, Elrod JK, Bray F, Vaccarella S, Gay C, Lu DJ, Chen MM, Chaturvedi AK, Goodman MT
J Natl Cancer Inst 2023 Dec 6;115(12):1544-1554. doi: 10.1093/jnci/djad169. PMID: 37603716Free PMC Article
The Role of Radiotherapy in the Definitive and Postoperative Treatment of Advanced Head and Neck Cancer.
Semrau R
Oncol Res Treat 2017;40(6):347-352. Epub 2017 May 17 doi: 10.1159/000477128. PMID: 28521321
Treatment deintensification strategies for HPV-associated head and neck carcinomas.
Quon H, Richmon JD
Otolaryngol Clin North Am 2012 Aug;45(4):845-61. doi: 10.1016/j.otc.2012.04.007. PMID: 22793856
(Pre)malignancies of the female anogenital tract in renal transplant recipients.
Meeuwis KA, van Rossum MM, Hoitsma AJ, de Hullu JA
Transplantation 2011 Jan 15;91(1):8-10. doi: 10.1097/tp.0b013e3181fbd008. PMID: 21452406
Cervical neoplasia. Pathogenesis, diagnosis, and management.
Robinson WR, Morris CB
Hematol Oncol Clin North Am 1996 Oct;10(5):1163-76. doi: 10.1016/s0889-8588(05)70391-9. PMID: 8880203

Diagnosis

Global prevalence of human papillomavirus-related oral and oropharyngeal squamous cell carcinomas: a systematic review and meta-analysis.
Fonsêca TC, Jural LA, Marañón-Vásquez GA, Magno MB, Roza ALOC, Ferreira DMTP, Maia LC, Romañach MJ, Agostini M, Abrahão AC
Clin Oral Investig 2023 Dec 30;28(1):62. doi: 10.1007/s00784-023-05425-0. PMID: 38158517
Inflammation and cancer.
Murata M
Environ Health Prev Med 2018 Oct 20;23(1):50. doi: 10.1186/s12199-018-0740-1. PMID: 30340457Free PMC Article
Human papillomavirus-related oropharyngeal cancer.
Taberna M, Mena M, Pavón MA, Alemany L, Gillison ML, Mesía R
Ann Oncol 2017 Oct 1;28(10):2386-2398. doi: 10.1093/annonc/mdx304. PMID: 28633362
Human Papillomavirus-Related Head and Neck Cancer.
Wagner S, Sharma SJ, Wuerdemann N, Knuth J, Reder H, Wittekindt C, Klussmann JP
Oncol Res Treat 2017;40(6):334-340. Epub 2017 May 19 doi: 10.1159/000477252. PMID: 28521311
(Pre)malignancies of the female anogenital tract in renal transplant recipients.
Meeuwis KA, van Rossum MM, Hoitsma AJ, de Hullu JA
Transplantation 2011 Jan 15;91(1):8-10. doi: 10.1097/tp.0b013e3181fbd008. PMID: 21452406

Therapy

Hypoxia-Directed Treatment of Human Papillomavirus-Related Oropharyngeal Carcinoma.
Lee NY, Sherman EJ, Schöder H, Wray R, Boyle JO, Singh B, Grkovski M, Paudyal R, Cunningham L, Zhang Z, Hatzoglou V, Katabi N, Diplas BH, Han J, Imber BS, Pham K, Yu Y, Zakeri K, McBride SM, Kang JJ, Tsai CJ, Chen LC, Gelblum DY, Shah JP, Ganly I, Cohen MA, Cracchiolo JR, Morris LGT, Dunn LA, Michel LS, Fetten JV, Kripani A, Pfister DG, Ho AL, Shukla-Dave A, Humm JL, Powell SN, Li BT, Reis-Filho JS, Diaz LA, Wong RJ, Riaz N
J Clin Oncol 2024 Mar 10;42(8):940-950. Epub 2024 Jan 19 doi: 10.1200/JCO.23.01308. PMID: 38241600Free PMC Article
Human papillomavirus-related oropharyngeal carcinoma.
Saito Y, Homma A, Kiyota N, Tahara M, Hanai N, Asakage T, Matsuura K, Ota I, Yokota T, Sano D, Kodaira T, Motegi A, Yasuda K, Takahashi S, Tanaka K, Onoe T, Okano S, Imamura Y, Ariizumi Y, Hayashi R
Jpn J Clin Oncol 2022 Jul 8;52(7):700-706. doi: 10.1093/jjco/hyac049. PMID: 35383359
Surgical Options for Locally Advanced Oropharyngeal Cancer.
Qureshi HA, Abouyared M, Barber B, Houlton JJ
Curr Treat Options Oncol 2019 Apr 1;20(5):36. doi: 10.1007/s11864-019-0621-x. PMID: 30931485
Human Papillomavirus-Related Cancers.
Li Y, Xu C
Adv Exp Med Biol 2017;1018:23-34. doi: 10.1007/978-981-10-5765-6_3. PMID: 29052130
(Pre)malignancies of the female anogenital tract in renal transplant recipients.
Meeuwis KA, van Rossum MM, Hoitsma AJ, de Hullu JA
Transplantation 2011 Jan 15;91(1):8-10. doi: 10.1097/tp.0b013e3181fbd008. PMID: 21452406

Prognosis

Global epidemiologic patterns of oropharyngeal cancer incidence trends.
Zumsteg ZS, Luu M, Rosenberg PS, Elrod JK, Bray F, Vaccarella S, Gay C, Lu DJ, Chen MM, Chaturvedi AK, Goodman MT
J Natl Cancer Inst 2023 Dec 6;115(12):1544-1554. doi: 10.1093/jnci/djad169. PMID: 37603716Free PMC Article
Human papillomavirus-related oropharyngeal carcinoma.
Saito Y, Homma A, Kiyota N, Tahara M, Hanai N, Asakage T, Matsuura K, Ota I, Yokota T, Sano D, Kodaira T, Motegi A, Yasuda K, Takahashi S, Tanaka K, Onoe T, Okano S, Imamura Y, Ariizumi Y, Hayashi R
Jpn J Clin Oncol 2022 Jul 8;52(7):700-706. doi: 10.1093/jjco/hyac049. PMID: 35383359
Human Papillomavirus-Related Neuroendocrine Carcinomas of the Head and Neck.
Westra WH
Head Neck Pathol 2018 Mar;12(1):9-12. Epub 2018 Mar 20 doi: 10.1007/s12105-018-0886-6. PMID: 29556964Free PMC Article
Human Papillomavirus-Related Head and Neck Cancer.
Wagner S, Sharma SJ, Wuerdemann N, Knuth J, Reder H, Wittekindt C, Klussmann JP
Oncol Res Treat 2017;40(6):334-340. Epub 2017 May 19 doi: 10.1159/000477252. PMID: 28521311
Cervical neoplasia. Pathogenesis, diagnosis, and management.
Robinson WR, Morris CB
Hematol Oncol Clin North Am 1996 Oct;10(5):1163-76. doi: 10.1016/s0889-8588(05)70391-9. PMID: 8880203

Clinical prediction guides

Global epidemiologic patterns of oropharyngeal cancer incidence trends.
Zumsteg ZS, Luu M, Rosenberg PS, Elrod JK, Bray F, Vaccarella S, Gay C, Lu DJ, Chen MM, Chaturvedi AK, Goodman MT
J Natl Cancer Inst 2023 Dec 6;115(12):1544-1554. doi: 10.1093/jnci/djad169. PMID: 37603716Free PMC Article
Diverse intratumoral heterogeneity and immune microenvironment of two HPV-related cervical cancer types revealed by single-cell RNA sequencing.
Li C, Liu D, Zhao Y, Ding Y, Hua K
J Med Virol 2023 Jun;95(6):e28857. doi: 10.1002/jmv.28857. PMID: 37287196
Human papillomavirus-related multiphenotypic sinonasal carcinoma.
Morishita Y, Sakashita S, Tomioka T, Okano W, Shinozaki T, Higashino T, Matsuura K, Hayashi R
Auris Nasus Larynx 2023 Feb;50(1):151-155. Epub 2021 Nov 4 doi: 10.1016/j.anl.2021.10.008. PMID: 34742620
Human Papillomavirus-Related Neuroendocrine Carcinomas of the Head and Neck.
Westra WH
Head Neck Pathol 2018 Mar;12(1):9-12. Epub 2018 Mar 20 doi: 10.1007/s12105-018-0886-6. PMID: 29556964Free PMC Article
Human papillomavirus-related oropharyngeal cancer.
Taberna M, Mena M, Pavón MA, Alemany L, Gillison ML, Mesía R
Ann Oncol 2017 Oct 1;28(10):2386-2398. doi: 10.1093/annonc/mdx304. PMID: 28633362

Recent systematic reviews

Global prevalence of human papillomavirus-related oral and oropharyngeal squamous cell carcinomas: a systematic review and meta-analysis.
Fonsêca TC, Jural LA, Marañón-Vásquez GA, Magno MB, Roza ALOC, Ferreira DMTP, Maia LC, Romañach MJ, Agostini M, Abrahão AC
Clin Oral Investig 2023 Dec 30;28(1):62. doi: 10.1007/s00784-023-05425-0. PMID: 38158517
Distant metastases in human papillomavirus-related oropharyngeal squamous cell carcinoma: Systematic review and meta-analysis.
Crossley JR, Nelson LL, Chou J, Maxwell JH
Head Neck 2023 Jan;45(1):275-282. Epub 2022 Oct 28 doi: 10.1002/hed.27230. PMID: 36306202
Radiological features of human papillomavirus-related multiphenotypic sinonasal carcinoma: systematic review and case series.
Baba A, Kurokawa R, Fukuda T, Fujioka H, Kurokawa M, Fukasawa N, Sonobe S, Omura K, Matsushima S, Ota Y, Yamauchi H, Shimizu K, Kurata N, Srinivasan A, Ojiri H
Neuroradiology 2022 Oct;64(10):2049-2058. Epub 2022 Jul 14 doi: 10.1007/s00234-022-03009-5. PMID: 35833947
Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma-An Even Broader Tumor Entity?
Zupancic M, Näsman A
Viruses 2021 Sep 17;13(9) doi: 10.3390/v13091861. PMID: 34578442Free PMC Article
Human papillomavirus related head and neck cancer survival: a systematic review and meta-analysis.
O'Rorke MA, Ellison MV, Murray LJ, Moran M, James J, Anderson LA
Oral Oncol 2012 Dec;48(12):1191-201. Epub 2012 Jul 28 doi: 10.1016/j.oraloncology.2012.06.019. PMID: 22841677

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