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Neoplasm of the posterior pituitary

MedGen UID:: 235368
•Concept ID:: C1334957
•: Neoplastic Process

Synonyms:	neoplasm of neurohypophysis; Neoplasm of the neurohypophysis; Neurohypophysis Neoplasm; Neurohypophysis neoplasm; neurohypophysis neoplasm; neurohypophysis neoplasm (disease); Neurohypophysis Tumor; Neurohypophysis tumor; neurohypophysis tumor; neurohypophysis tumour; Neurohypophysis tumour; Pituicyte Tumor; Pituicyte Tumor Family; PITUICYTOMA, benign; Posterior Pituitary Gland Neoplasm; posterior pituitary gland neoplasm; Posterior Pituitary Gland Tumor; posterior pituitary gland tumor; posterior pituitary gland tumour; Posterior Pituitary Neoplasm; posterior pituitary neoplasm; Posterior Pituitary Tumor; posterior pituitary tumor; posterior pituitary tumour; tumor of neurohypophysis; tumour of neurohypophysis

HPO:	HP:0011752
Monarch Initiative:	MONDO:0003257

Definition

The presence of a neoplasm (tumor) in the neurohypophysis, which is also known as the posterior lobe of the hypophysis. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVNeoplasm of the posterior pituitary

Abnormality of the nervous system
- Abnormal nervous system morphology
  - Morphological central nervous system abnormality
    - Abnormal brain morphology
      - Abnormal pituitary gland morphology
        Abnormal posterior pituitary morphogenesis
        Neoplasm of the posterior pituitary
        Ependymal Pituicytoma
        Neurohypophysis granular cell tumor
        Pituicytoma
        Spindle cell oncocytoma

Professional guidelines

PubMed

The Diagnosis and Treatment of Craniopharyngioma.

Müller HL
Neuroendocrinology 2020;110(9-10):753-766. Epub 2019 Nov 4 doi: 10.1159/000504512. PMID: 31678973

Treatment strategies for craniopharyngiomas.

Ottenhausen M, Rumalla K, La Corte E, Alalade A, Nair P, Forbes J, Ben Nsir A, Schwartz TH
J Neurosurg Sci 2019 Feb;63(1):83-87. Epub 2017 Sep 4 doi: 10.23736/S0390-5616.17.04171-6. PMID: 28869375

Management of diabetes insipidus and adipsia in the child.

Di Iorgi N, Morana G, Napoli F, Allegri AE, Rossi A, Maghnie M
Best Pract Res Clin Endocrinol Metab 2015 Jun;29(3):415-36. Epub 2015 May 9 doi: 10.1016/j.beem.2015.04.013. PMID: 26051300

See all (39)

Recent clinical studies

Etiology

Overview of the 2022 WHO Classification of Pituitary Tumors.

Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028

Modern endoscopic skull base neurosurgery.

Martinez-Perez R, Requena LC, Carrau RL, Prevedello DM
J Neurooncol 2021 Feb;151(3):461-475. Epub 2021 Feb 21 doi: 10.1007/s11060-020-03610-9. PMID: 33611712

Insights into non-classic and emerging causes of hypopituitarism.

Prodam F, Caputo M, Mele C, Marzullo P, Aimaretti G
Nat Rev Endocrinol 2021 Feb;17(2):114-129. Epub 2020 Nov 27 doi: 10.1038/s41574-020-00437-2. PMID: 33247226

Overview of the 2017 WHO Classification of Pituitary Tumors.

Mete O, Lopes MB
Endocr Pathol 2017 Sep;28(3):228-243. doi: 10.1007/s12022-017-9498-z. PMID: 28766057

Hypopituitarism.

Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067

See all (339)

Diagnosis

Overview of the 2022 WHO Classification of Pituitary Tumors.

Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028

The Diagnosis and Treatment of Craniopharyngioma.

Müller HL
Neuroendocrinology 2020;110(9-10):753-766. Epub 2019 Nov 4 doi: 10.1159/000504512. PMID: 31678973

Hypopituitarism.

Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067

Craniopharyngioma.

Müller HL
Endocr Rev 2014 Jun;35(3):513-43. Epub 2014 Jan 27 doi: 10.1210/er.2013-1115. PMID: 24467716

The oxytocin receptor system: structure, function, and regulation.

Gimpl G, Fahrenholz F
Physiol Rev 2001 Apr;81(2):629-83. doi: 10.1152/physrev.2001.81.2.629. PMID: 11274341

See all (476)

Therapy

Outcome after pediatric craniopharyngioma: the role of age at diagnosis and hypothalamic damage.

Beckhaus J, Friedrich C, Boekhoff S, Calaminus G, Bison B, Eveslage M, Timmermann B, Flitsch J, Müller HL
Eur J Endocrinol 2023 Mar 2;188(3) doi: 10.1093/ejendo/lvad027. PMID: 36857103

Insights into non-classic and emerging causes of hypopituitarism.

Prodam F, Caputo M, Mele C, Marzullo P, Aimaretti G
Nat Rev Endocrinol 2021 Feb;17(2):114-129. Epub 2020 Nov 27 doi: 10.1038/s41574-020-00437-2. PMID: 33247226

Hypopituitarism.

Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067

Management of diabetes insipidus and adipsia in the child.

Di Iorgi N, Morana G, Napoli F, Allegri AE, Rossi A, Maghnie M
Best Pract Res Clin Endocrinol Metab 2015 Jun;29(3):415-36. Epub 2015 May 9 doi: 10.1016/j.beem.2015.04.013. PMID: 26051300

Craniopharyngioma.

Müller HL
Endocr Rev 2014 Jun;35(3):513-43. Epub 2014 Jan 27 doi: 10.1210/er.2013-1115. PMID: 24467716

See all (176)

Prognosis

Metastatic Spread to the Pituitary.

Shimon I
Neuroendocrinology 2020;110(9-10):805-808. Epub 2020 Feb 27 doi: 10.1159/000506810. PMID: 32101869

Tumors of the Neurohypophysis: One Unit's Experience and Literature Review.

Borg A, Jaunmuktane Z, Dorward N
World Neurosurg 2020 Feb;134:e968-e978. Epub 2019 Nov 14 doi: 10.1016/j.wneu.2019.11.043. PMID: 31734425

Hypopituitarism.

Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067

Craniopharyngioma.

Müller HL
Endocr Rev 2014 Jun;35(3):513-43. Epub 2014 Jan 27 doi: 10.1210/er.2013-1115. PMID: 24467716

Neurology of pregnancy.

Block HS, Biller J
Handb Clin Neurol 2014;121:1595-622. doi: 10.1016/B978-0-7020-4088-7.00105-X. PMID: 24365437

See all (209)

Clinical prediction guides

Outcome after pediatric craniopharyngioma: the role of age at diagnosis and hypothalamic damage.

Beckhaus J, Friedrich C, Boekhoff S, Calaminus G, Bison B, Eveslage M, Timmermann B, Flitsch J, Müller HL
Eur J Endocrinol 2023 Mar 2;188(3) doi: 10.1093/ejendo/lvad027. PMID: 36857103

Correlation of Pituitary Descent and Diabetes Insipidus After Transsphenoidal Pituitary Macroadenoma Resection.

Ma J, Gooderham P, Akagami R, Makarenko S
Neurosurgery 2023 Jun 1;92(6):1269-1275. Epub 2023 Jan 18 doi: 10.1227/neu.0000000000002360. PMID: 36700759

Imaging findings in hypophysitis: a review.

Caranci F, Leone G, Ponsiglione A, Muto M, Tortora F, Muto M, Cirillo S, Brunese L, Cerase A
Radiol Med 2020 Mar;125(3):319-328. Epub 2019 Dec 20 doi: 10.1007/s11547-019-01120-x. PMID: 31863360

Hypopituitarism.

Higham CE, Johannsson G, Shalet SM
Lancet 2016 Nov 12;388(10058):2403-2415. Epub 2016 Mar 31 doi: 10.1016/S0140-6736(16)30053-8. PMID: 27041067

Management of diabetes insipidus and adipsia in the child.

Di Iorgi N, Morana G, Napoli F, Allegri AE, Rossi A, Maghnie M
Best Pract Res Clin Endocrinol Metab 2015 Jun;29(3):415-36. Epub 2015 May 9 doi: 10.1016/j.beem.2015.04.013. PMID: 26051300

See all (182)

Recent systematic reviews

Primary Tumors of the Posterior Pituitary Gland: A Systematic Review of the Literature in Light of the New 2017 World Health Organization Classification of Pituitary Tumors.

Whipple SG, Savardekar AR, Rao S, Mahadevan A, Guthikonda B, Kosty JA
World Neurosurg 2021 Jan;145:148-158. Epub 2020 Sep 8 doi: 10.1016/j.wneu.2020.09.023. PMID: 32916355

Granular cell tumors of the sellar region: what should be done after subtotal resection? A systematic review.

Rubino F, Martinez-Perez R, Vieira S, Voscoboinik DS, Mural M, Orr AJ, Hardesty DA, Carrau RL, Prevedello DM
Pituitary 2020 Dec;23(6):721-732. doi: 10.1007/s11102-020-01068-6. PMID: 32740679

Primary tumors of the posterior pituitary: A systematic review.

Guerrero-Pérez F, Marengo AP, Vidal N, Iglesias P, Villabona C
Rev Endocr Metab Disord 2019 Jun;20(2):219-238. doi: 10.1007/s11154-019-09484-1. PMID: 30864049

Granular Cell Tumor of the Neurohypophysis: 3 Cases and a Systematic Literature Review of 98 Cases.

Zhang Y, Teng Y, Zhu H, Lu L, Deng K, Pan H, Yao Y
World Neurosurg 2018 Oct;118:e621-e630. Epub 2018 Jul 11 doi: 10.1016/j.wneu.2018.07.004. PMID: 30017767

Infundibulo-tuberal or not strictly intraventricular craniopharyngioma: evidence for a major topographical category.

Pascual JM, Prieto R, Carrasco R
Acta Neurochir (Wien) 2011 Dec;153(12):2403-25; discussion 2426. Epub 2011 Sep 15 doi: 10.1007/s00701-011-1149-4. PMID: 21918833

See all (11)

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Neoplasm of the posterior pituitary

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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