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Abnormal pituitary gland morphology

MedGen UID:
1843446
•Concept ID:
C5779790
•
Anatomical Abnormality
Synonym: Abnormality of the pituitary gland
 
HPO: HP:0012503

Definition

An anomaly of the pituitary gland. [from HPO]

Professional guidelines

PubMed

MANAGEMENT OF ENDOCRINE DISEASE: Differential diagnosis, investigation and therapy of bilateral adrenal incidentalomas.
Bourdeau I, El Ghorayeb N, Gagnon N, Lacroix A
Eur J Endocrinol 2018 Aug;179(2):R57-R67. Epub 2018 May 10 doi: 10.1530/EJE-18-0296. PMID: 29748231
MANAGEMENT OF ENDOCRINE DISEASE: Pituitary 'incidentaloma': neuroradiological assessment and differential diagnosis.
Vasilev V, Rostomyan L, Daly AF, Potorac I, Zacharieva S, Bonneville JF, Beckers A
Eur J Endocrinol 2016 Oct;175(4):R171-84. Epub 2016 Apr 11 doi: 10.1530/EJE-15-1272. PMID: 27068689
Primary amenorrhea: diagnosis and management.
Marsh CA, Grimstad FW
Obstet Gynecol Surv 2014 Oct;69(10):603-12. doi: 10.1097/OGX.0000000000000111. PMID: 25336070

Recent clinical studies

Etiology

Phakomatoses and Endocrine Gland Tumors: Noteworthy and (Not so) Rare Associations.
Chevalier B, Dupuis H, Jannin A, Lemaitre M, Do Cao C, Cardot-Bauters C, Espiard S, Vantyghem MC
Front Endocrinol (Lausanne) 2021;12:678869. Epub 2021 May 6 doi: 10.3389/fendo.2021.678869. PMID: 34025587Free PMC Article
Interconnection between circadian clocks and thyroid function.
Ikegami K, Refetoff S, Van Cauter E, Yoshimura T
Nat Rev Endocrinol 2019 Oct;15(10):590-600. Epub 2019 Aug 12 doi: 10.1038/s41574-019-0237-z. PMID: 31406343Free PMC Article
Pituitary dysfunction in granulomatosis with polyangiitis.
Esposito D, Trimpou P, Giugliano D, Dehlin M, Ragnarsson O
Pituitary 2017 Oct;20(5):594-601. doi: 10.1007/s11102-017-0811-0. PMID: 28540625Free PMC Article
Complications of acromegaly: thyroid and colon.
Tirosh A, Shimon I
Pituitary 2017 Feb;20(1):70-75. doi: 10.1007/s11102-016-0744-z. PMID: 27631334
Rathke's cleft cyst.
Larkin S, Karavitaki N, Ansorge O
Handb Clin Neurol 2014;124:255-69. doi: 10.1016/B978-0-444-59602-4.00017-4. PMID: 25248592

Diagnosis

Neuroimaging of the Pituitary Gland: Practical Anatomy and Pathology.
Chapman PR, Singhal A, Gaddamanugu S, Prattipati V
Radiol Clin North Am 2020 Nov;58(6):1115-1133. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.009. PMID: 33040852
Sellar Tumors.
Schwetye KE, Dahiya SM
Surg Pathol Clin 2020 Jun;13(2):305-329. doi: 10.1016/j.path.2020.02.006. PMID: 32389269
Diabetes insipidus.
Christ-Crain M, Bichet DG, Fenske WK, Goldman MB, Rittig S, Verbalis JG, Verkman AS
Nat Rev Dis Primers 2019 Aug 8;5(1):54. doi: 10.1038/s41572-019-0103-2. PMID: 31395885
Rathke's cleft cyst.
Larkin S, Karavitaki N, Ansorge O
Handb Clin Neurol 2014;124:255-69. doi: 10.1016/B978-0-444-59602-4.00017-4. PMID: 25248592
Neuro-osteology.
Kjaer I
Crit Rev Oral Biol Med 1998;9(2):224-44. doi: 10.1177/10454411980090020501. PMID: 9603237

Therapy

Endocrine and Metabolic Manifestations of Snakebite Envenoming.
Bhattacharya S, Krishnamurthy A, Gopalakrishnan M, Kalra S, Kantroo V, Aggarwal S, Surana V
Am J Trop Med Hyg 2020 Oct;103(4):1388-1396. doi: 10.4269/ajtmh.20-0161. PMID: 32602439Free PMC Article
Pituitary dysfunction in granulomatosis with polyangiitis.
Esposito D, Trimpou P, Giugliano D, Dehlin M, Ragnarsson O
Pituitary 2017 Oct;20(5):594-601. doi: 10.1007/s11102-017-0811-0. PMID: 28540625Free PMC Article
Diabetes insipidus following resection of pituitary tumors.
Schreckinger M, Szerlip N, Mittal S
Clin Neurol Neurosurg 2013 Feb;115(2):121-6. Epub 2012 Aug 24 doi: 10.1016/j.clineuro.2012.08.009. PMID: 22921808
Spontaneous intracranial hypotension.
Mokri B
Curr Neurol Neurosci Rep 2001 Mar;1(2):109-17. doi: 10.1007/s11910-001-0005-y. PMID: 11898506
Adolescent menstrual irregularity.
Mansfield MJ, Emans SJ
J Reprod Med 1984 Jun;29(6):399-410. PMID: 6379175

Prognosis

Architects of Pituitary Tumour Growth.
Sabatino ME, Grondona E, De Paul AL
Front Endocrinol (Lausanne) 2022;13:924942. Epub 2022 Jun 28 doi: 10.3389/fendo.2022.924942. PMID: 35837315Free PMC Article
What to Do with Incidentally Discovered Pituitary Abnormalities?
Langlois F, Fleseriu M
Med Clin North Am 2021 Nov;105(6):1081-1098. Epub 2021 Sep 9 doi: 10.1016/j.mcna.2021.05.015. PMID: 34688416
Phakomatoses and Endocrine Gland Tumors: Noteworthy and (Not so) Rare Associations.
Chevalier B, Dupuis H, Jannin A, Lemaitre M, Do Cao C, Cardot-Bauters C, Espiard S, Vantyghem MC
Front Endocrinol (Lausanne) 2021;12:678869. Epub 2021 May 6 doi: 10.3389/fendo.2021.678869. PMID: 34025587Free PMC Article
Rathke's cleft cysts.
Kanter AS, Sansur CA, Jane JAJ Jr, Laws ERJ Jr
Front Horm Res 2006;34:127-157. doi: 10.1159/000091579. PMID: 16474219
Neuro-osteology.
Kjaer I
Crit Rev Oral Biol Med 1998;9(2):224-44. doi: 10.1177/10454411980090020501. PMID: 9603237

Clinical prediction guides

Architects of Pituitary Tumour Growth.
Sabatino ME, Grondona E, De Paul AL
Front Endocrinol (Lausanne) 2022;13:924942. Epub 2022 Jun 28 doi: 10.3389/fendo.2022.924942. PMID: 35837315Free PMC Article
Endocrine and Metabolic Manifestations of Snakebite Envenoming.
Bhattacharya S, Krishnamurthy A, Gopalakrishnan M, Kalra S, Kantroo V, Aggarwal S, Surana V
Am J Trop Med Hyg 2020 Oct;103(4):1388-1396. doi: 10.4269/ajtmh.20-0161. PMID: 32602439Free PMC Article
Normal neuroanatomical variants that may be misinterpreted as disease entities.
Ramji S, Touska P, Rich P, MacKinnon AD
Clin Radiol 2017 Oct;72(10):810-825. Epub 2017 Jul 23 doi: 10.1016/j.crad.2017.06.118. PMID: 28747250
Complications of acromegaly: thyroid and colon.
Tirosh A, Shimon I
Pituitary 2017 Feb;20(1):70-75. doi: 10.1007/s11102-016-0744-z. PMID: 27631334
Rathke's cleft cysts.
Kanter AS, Sansur CA, Jane JAJ Jr, Laws ERJ Jr
Front Horm Res 2006;34:127-157. doi: 10.1159/000091579. PMID: 16474219

Recent systematic reviews

Primary Tumors of the Posterior Pituitary Gland: A Systematic Review of the Literature in Light of the New 2017 World Health Organization Classification of Pituitary Tumors.
Whipple SG, Savardekar AR, Rao S, Mahadevan A, Guthikonda B, Kosty JA
World Neurosurg 2021 Jan;145:148-158. Epub 2020 Sep 8 doi: 10.1016/j.wneu.2020.09.023. PMID: 32916355
Pituitary dysfunction in granulomatosis with polyangiitis.
Esposito D, Trimpou P, Giugliano D, Dehlin M, Ragnarsson O
Pituitary 2017 Oct;20(5):594-601. doi: 10.1007/s11102-017-0811-0. PMID: 28540625Free PMC Article
Case Report of a Primary Pituitary Abscess and Systematic Literature Review of Pituitary Abscess with a Focus on Patient Outcomes.
Agyei JO, Lipinski LJ, Leonardo J
World Neurosurg 2017 May;101:76-92. Epub 2017 Jan 31 doi: 10.1016/j.wneu.2017.01.077. PMID: 28153622
Ectopic ACTH-secreting pituitary adenoma of the sphenoid sinus: case report of endoscopic endonasal resection and systematic review of the literature.
Seltzer J, Lucas J, Commins D, Lerner O, Lerner A, Carmichael JD, Zada G
Neurosurg Focus 2015 Feb;38(2):E10. doi: 10.3171/2014.10.FOCUS14685. PMID: 25639312
Cerebral aneurysms with intrasellar extension: a systematic review of clinical, anatomical, and treatment characteristics.
Hanak BW, Zada G, Nayar VV, Thiex R, Du R, Day AL, Laws ER
J Neurosurg 2012 Jan;116(1):164-78. Epub 2011 Nov 4 doi: 10.3171/2011.9.JNS11380. PMID: 22054212

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