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Pancreatic Intraductal Neoplasm

MedGen UID:
459414
•Concept ID:
C2987188
•
Neoplastic Process
Synonyms: Intraductal Neoplasm, Pancreatic; Intraductal Neoplasms, Pancreatic; Neoplasm, Pancreatic Intraductal; Pancreatic Intraductal Neoplasms

Definition

A group of cystic or mass-forming epithelial neoplasms that arise from the exocrine pancreas, exhibit ductal differentiation, and grow mostly within the pancreatic ducts. This group includes the pancreatic intraductal papillary mucinous neoplasms and the pancreatic intraductal tubulopapillary neoplasms. [from NCI]

Professional guidelines

PubMed

Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?
Pozzi Mucelli RM, Moro CF, Del Chiaro M, Valente R, Blomqvist L, Papanikolaou N, Löhr JM, Kartalis N
Eur Radiol 2022 Aug;32(8):5144-5155. Epub 2022 Mar 11 doi: 10.1007/s00330-022-08650-5. PMID: 35275259Free PMC Article

Recent clinical studies

Etiology

Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?
Pozzi Mucelli RM, Moro CF, Del Chiaro M, Valente R, Blomqvist L, Papanikolaou N, Löhr JM, Kartalis N
Eur Radiol 2022 Aug;32(8):5144-5155. Epub 2022 Mar 11 doi: 10.1007/s00330-022-08650-5. PMID: 35275259Free PMC Article
An extremely rare case who underwent total remnant pancreatectomy due to recurrent pancreatic metastasis of intraductal tubulopapillary neoplasm.
Umemura A, Ishida K, Nitta H, Takahara T, Hasegawa Y, Makabe K, Sugai T, Sasaki A
Clin J Gastroenterol 2019 Apr;12(2):153-159. Epub 2018 Oct 4 doi: 10.1007/s12328-018-0913-x. PMID: 30284703
Intraductal Tubulopapillary Neoplasm of the Pancreas: A Clinicopathologic and Immunohistochemical Analysis of 33 Cases.
Basturk O, Adsay V, Askan G, Dhall D, Zamboni G, Shimizu M, Cymes K, Carneiro F, Balci S, Sigel C, Reid MD, Esposito I, Baldaia H, Allen P, Klöppel G, Klimstra DS
Am J Surg Pathol 2017 Mar;41(3):313-325. doi: 10.1097/PAS.0000000000000782. PMID: 27984235Free PMC Article

Diagnosis

Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?
Pozzi Mucelli RM, Moro CF, Del Chiaro M, Valente R, Blomqvist L, Papanikolaou N, Löhr JM, Kartalis N
Eur Radiol 2022 Aug;32(8):5144-5155. Epub 2022 Mar 11 doi: 10.1007/s00330-022-08650-5. PMID: 35275259Free PMC Article
An extremely rare case who underwent total remnant pancreatectomy due to recurrent pancreatic metastasis of intraductal tubulopapillary neoplasm.
Umemura A, Ishida K, Nitta H, Takahara T, Hasegawa Y, Makabe K, Sugai T, Sasaki A
Clin J Gastroenterol 2019 Apr;12(2):153-159. Epub 2018 Oct 4 doi: 10.1007/s12328-018-0913-x. PMID: 30284703
Intraductal Tubulopapillary Neoplasm of the Pancreas: A Clinicopathologic and Immunohistochemical Analysis of 33 Cases.
Basturk O, Adsay V, Askan G, Dhall D, Zamboni G, Shimizu M, Cymes K, Carneiro F, Balci S, Sigel C, Reid MD, Esposito I, Baldaia H, Allen P, Klöppel G, Klimstra DS
Am J Surg Pathol 2017 Mar;41(3):313-325. doi: 10.1097/PAS.0000000000000782. PMID: 27984235Free PMC Article
A case of MUC5AC-positive intraductal neoplasm of the pancreas classified as an intraductal tubulopapillary neoplasm?
Muraki T, Uehara T, Sano K, Oota H, Yoshizawa A, Asaka S, Tateishi A, Otsuki T, Shingu K, Matoba H, Kobayashi S, Ichimata S, Watanabe T, Itou T, Tanaka E
Pathol Res Pract 2015 Dec;211(12):1034-9. Epub 2015 Oct 30 doi: 10.1016/j.prp.2015.10.009. PMID: 26586167

Prognosis

Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?
Pozzi Mucelli RM, Moro CF, Del Chiaro M, Valente R, Blomqvist L, Papanikolaou N, Löhr JM, Kartalis N
Eur Radiol 2022 Aug;32(8):5144-5155. Epub 2022 Mar 11 doi: 10.1007/s00330-022-08650-5. PMID: 35275259Free PMC Article
Intraductal Tubulopapillary Neoplasm of the Pancreas: A Clinicopathologic and Immunohistochemical Analysis of 33 Cases.
Basturk O, Adsay V, Askan G, Dhall D, Zamboni G, Shimizu M, Cymes K, Carneiro F, Balci S, Sigel C, Reid MD, Esposito I, Baldaia H, Allen P, Klöppel G, Klimstra DS
Am J Surg Pathol 2017 Mar;41(3):313-325. doi: 10.1097/PAS.0000000000000782. PMID: 27984235Free PMC Article

Clinical prediction guides

Branch-duct intraductal papillary mucinous neoplasm (IPMN): Are cyst volumetry and other novel imaging features able to improve malignancy prediction compared to well-established resection criteria?
Pozzi Mucelli RM, Moro CF, Del Chiaro M, Valente R, Blomqvist L, Papanikolaou N, Löhr JM, Kartalis N
Eur Radiol 2022 Aug;32(8):5144-5155. Epub 2022 Mar 11 doi: 10.1007/s00330-022-08650-5. PMID: 35275259Free PMC Article

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