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Cutaneous cyst

MedGen UID:
66022
•Concept ID:
C0241060
•
Anatomical Abnormality
Synonym: Cutaneous cysts
SNOMED CT: Cyst of skin (285302001); Cutaneous cyst (285302001)
 
HPO: HP:0025245

Definition

A hollow mass located in the skin that is surrounded by an epithelium-lined wall and is well demarcated from the adjacent tissue. Cysts are often said to be sac-like and may contain serous liquid or semisolid material. [from HPO]

Professional guidelines

PubMed

European consensus-based interdisciplinary guideline for diagnosis and treatment of basal cell carcinoma-update 2023.
Peris K, Fargnoli MC, Kaufmann R, Arenberger P, Bastholt L, Seguin NB, Bataille V, Brochez L, Del Marmol V, Dummer R, Forsea AM, Gaudy-Marqueste C, Harwood CA, Hauschild A, Höller C, Kandolf L, Kellerners-Smeets NWJ, Lallas A, Leiter U, Malvehy J, Marinović B, Mijuskovic Z, Moreno-Ramirez D, Nagore E, Nathan P, Stratigos AJ, Stockfleth E, Tagliaferri L, Trakatelli M, Vieira R, Zalaudek I, Garbe C; EADO”A, EDF”B, ESTRO”C, UEMS”D and EADV”E
Eur J Cancer 2023 Oct;192:113254. Epub 2023 Jul 28 doi: 10.1016/j.ejca.2023.113254. PMID: 37604067
European consensus-based interdisciplinary guideline for melanoma. Part 1: Diagnostics: Update 2022.
Garbe C, Amaral T, Peris K, Hauschild A, Arenberger P, Basset-Seguin N, Bastholt L, Bataille V, Del Marmol V, Dréno B, Fargnoli MC, Forsea AM, Grob JJ, Höller C, Kaufmann R, Kelleners-Smeets N, Lallas A, Lebbé C, Lytvynenko B, Malvehy J, Moreno-Ramirez D, Nathan P, Pellacani G, Saiag P, Stratigos AJ, Van Akkooi ACJ, Vieira R, Zalaudek I, Lorigan P; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO), and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2022 Jul;170:236-255. Epub 2022 May 12 doi: 10.1016/j.ejca.2022.03.008. PMID: 35570085
The Diagnosis and Management of Neurofibromatosis Type 1.
Ly KI, Blakeley JO
Med Clin North Am 2019 Nov;103(6):1035-1054. doi: 10.1016/j.mcna.2019.07.004. PMID: 31582003

Recent clinical studies

Etiology

Operative outcome of mucous cyst of lesser toes: A comparison between cyst excision with osteophytectomy and distal interphalangeal fusion.
Choi JY, Lee SS, Jung YH, Suh JS
Foot Ankle Surg 2023 Apr;29(3):256-260. Epub 2023 Feb 10 doi: 10.1016/j.fas.2023.02.003. PMID: 36806441
Skin metastasis: a pathologist's perspective.
Hussein MR
J Cutan Pathol 2010 Sep;37(9):e1-20. Epub 2009 Nov 17 doi: 10.1111/j.1600-0560.2009.01469.x. PMID: 19922483
APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis.
Giardiello FM, Petersen GM, Piantadosi S, Gruber SB, Traboulsi EI, Offerhaus GJ, Muro K, Krush AJ, Booker SV, Luce MC, Laken SJ, Kinzler KW, Vogelstein B, Hamilton SR
Gut 1997 Apr;40(4):521-5. doi: 10.1136/gut.40.4.521. PMID: 9176082Free PMC Article

Diagnosis

Ciliated Cyst of the Vulva-A Case Report.
Ghosh M, Bitetti S, Busby G
J Pediatr Adolesc Gynecol 2020 Dec;33(6):730-732. Epub 2020 Aug 8 doi: 10.1016/j.jpag.2020.08.006. PMID: 32781235
Are mothers always right? When acute meningitis is something more.
Gomes C, Romão P, Miguens J, Mouzinho A
BMJ Case Rep 2015 Oct 13;2015 doi: 10.1136/bcr-2015-211658. PMID: 26464408Free PMC Article
Two cases of steatocystoma simplex in infants.
Sunohara M, Ozawa T, Morimoto K, Tateishi C, Ishii M
Dermatol Online J 2012 Jul 15;18(7):2. PMID: 22863624
Skin metastasis: a pathologist's perspective.
Hussein MR
J Cutan Pathol 2010 Sep;37(9):e1-20. Epub 2009 Nov 17 doi: 10.1111/j.1600-0560.2009.01469.x. PMID: 19922483
Follicular hybrid cysts. An expanded spectrum.
Requena L, Sánchez Yus E
Am J Dermatopathol 1991 Jun;13(3):228-33. doi: 10.1097/00000372-199106000-00003. PMID: 1714246

Therapy

Skin metastasis: a pathologist's perspective.
Hussein MR
J Cutan Pathol 2010 Sep;37(9):e1-20. Epub 2009 Nov 17 doi: 10.1111/j.1600-0560.2009.01469.x. PMID: 19922483

Prognosis

Skin metastasis: a pathologist's perspective.
Hussein MR
J Cutan Pathol 2010 Sep;37(9):e1-20. Epub 2009 Nov 17 doi: 10.1111/j.1600-0560.2009.01469.x. PMID: 19922483

Clinical prediction guides

Operative outcome of mucous cyst of lesser toes: A comparison between cyst excision with osteophytectomy and distal interphalangeal fusion.
Choi JY, Lee SS, Jung YH, Suh JS
Foot Ankle Surg 2023 Apr;29(3):256-260. Epub 2023 Feb 10 doi: 10.1016/j.fas.2023.02.003. PMID: 36806441
Spectrum of Hybrid Cysts and Their Clinical Significance.
Chang RS, Yao XF, Wu YH
Am J Dermatopathol 2018 Jun;40(6):397-400. doi: 10.1097/DAD.0000000000001006. PMID: 28937429
Are mothers always right? When acute meningitis is something more.
Gomes C, Romão P, Miguens J, Mouzinho A
BMJ Case Rep 2015 Oct 13;2015 doi: 10.1136/bcr-2015-211658. PMID: 26464408Free PMC Article
Skin metastasis: a pathologist's perspective.
Hussein MR
J Cutan Pathol 2010 Sep;37(9):e1-20. Epub 2009 Nov 17 doi: 10.1111/j.1600-0560.2009.01469.x. PMID: 19922483
Cutaneous cysts of Gardner's syndrome are similar to follicular stem cells.
Narisawa Y, Kohda H
J Cutan Pathol 1995 Apr;22(2):115-21. doi: 10.1111/j.1600-0560.1995.tb01392.x. PMID: 7560342

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