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Physiological sexual disorder

MedGen UID:
66756
•Concept ID:
C0237873
•
Pathologic Function
Synonyms: Physiological Sexual Disorder; Physiological Sexual Disorders; Physiological Sexual Dysfunction; Physiological Sexual Dysfunctions; Sex Disorders; Sexual Disorder, Physiological; Sexual Disorders, Physiological; Sexual Dysfunction, Physiological; Sexual Dysfunctions, Physiological
 
Monarch Initiative: MONDO:0002134

Definition

Physiological disturbances in normal sexual performance in either the male or the female. [from MONDO]

Professional guidelines

PubMed

Medical Treatment of Female Sexual Dysfunction.
Nappi RE, Tiranini L, Martini E, Bosoni D, Righi A, Cucinella L
Urol Clin North Am 2022 May;49(2):299-307. doi: 10.1016/j.ucl.2022.02.001. PMID: 35428435
Global Consensus Position Statement on the Use of Testosterone Therapy for Women.
Davis SR, Baber R, Panay N, Bitzer J, Perez SC, Islam RM, Kaunitz AM, Kingsberg SA, Lambrinoudaki I, Liu J, Parish SJ, Pinkerton J, Rymer J, Simon JA, Vignozzi L, Wierman ME
J Clin Endocrinol Metab 2019 Oct 1;104(10):4660-4666. doi: 10.1210/jc.2019-01603. PMID: 31498871Free PMC Article
Management of the Perimenopause.
Delamater L, Santoro N
Clin Obstet Gynecol 2018 Sep;61(3):419-432. doi: 10.1097/GRF.0000000000000389. PMID: 29952797Free PMC Article

Recent clinical studies

Etiology

Post-SSRI Sexual Dysfunction (PSSD): Biological Plausibility, Symptoms, Diagnosis, and Presumed Risk Factors.
Peleg LC, Rabinovitch D, Lavie Y, Rabbie DM, Horowitz I, Fruchter E, Gruenwald I
Sex Med Rev 2022 Jan;10(1):91-98. Epub 2021 Oct 7 doi: 10.1016/j.sxmr.2021.07.001. PMID: 34627736
Antidepressant-induced sexual dysfunction.
Rothmore J
Med J Aust 2020 Apr;212(7):329-334. Epub 2020 Mar 15 doi: 10.5694/mja2.50522. PMID: 32172535
Sexual dysfunction and related factors in pregnancy and postpartum: a systematic review and meta-analysis protocol.
Banaei M, Azizi M, Moridi A, Dashti S, Yabandeh AP, Roozbeh N
Syst Rev 2019 Jul 5;8(1):161. doi: 10.1186/s13643-019-1079-4. PMID: 31277721Free PMC Article
Male sexual dysfunction: A review of literature on its pathological mechanisms, potential risk factors, and herbal drug intervention.
Chen L, Shi GR, Huang DD, Li Y, Ma CC, Shi M, Su BX, Shi GJ
Biomed Pharmacother 2019 Apr;112:108585. Epub 2019 Feb 21 doi: 10.1016/j.biopha.2019.01.046. PMID: 30798136
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article

Diagnosis

Female Sexual Dysfunction.
Reed MA
Clin Plast Surg 2022 Oct;49(4):495-504. Epub 2022 Aug 17 doi: 10.1016/j.cps.2022.06.009. PMID: 36162944
Medical Treatment of Female Sexual Dysfunction.
Nappi RE, Tiranini L, Martini E, Bosoni D, Righi A, Cucinella L
Urol Clin North Am 2022 May;49(2):299-307. doi: 10.1016/j.ucl.2022.02.001. PMID: 35428435
Post-SSRI Sexual Dysfunction (PSSD): Biological Plausibility, Symptoms, Diagnosis, and Presumed Risk Factors.
Peleg LC, Rabinovitch D, Lavie Y, Rabbie DM, Horowitz I, Fruchter E, Gruenwald I
Sex Med Rev 2022 Jan;10(1):91-98. Epub 2021 Oct 7 doi: 10.1016/j.sxmr.2021.07.001. PMID: 34627736
Female Sexual Dysfunction.
Clayton AH, Valladares Juarez EM
Med Clin North Am 2019 Jul;103(4):681-698. doi: 10.1016/j.mcna.2019.02.008. PMID: 31078200
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article

Therapy

Antidepressant-induced sexual dysfunction.
Rothmore J
Med J Aust 2020 Apr;212(7):329-334. Epub 2020 Mar 15 doi: 10.5694/mja2.50522. PMID: 32172535
Post-finasteride syndrome: a surmountable challenge for clinicians.
Traish AM
Fertil Steril 2020 Jan;113(1):21-50. doi: 10.1016/j.fertnstert.2019.11.030. PMID: 32033719
Sexual Health in Menopause.
Scavello I, Maseroli E, Di Stasi V, Vignozzi L
Medicina (Kaunas) 2019 Sep 2;55(9) doi: 10.3390/medicina55090559. PMID: 31480774Free PMC Article
Post-SSRI Sexual Dysfunction: A Literature Review.
Bala A, Nguyen HMT, Hellstrom WJG
Sex Med Rev 2018 Jan;6(1):29-34. Epub 2017 Aug 1 doi: 10.1016/j.sxmr.2017.07.002. PMID: 28778697
Use of bupropion in combination with serotonin reuptake inhibitors.
Zisook S, Rush AJ, Haight BR, Clines DC, Rockett CB
Biol Psychiatry 2006 Feb 1;59(3):203-10. Epub 2005 Sep 13 doi: 10.1016/j.biopsych.2005.06.027. PMID: 16165100

Prognosis

Sexual dysfunction and related factors in pregnancy and postpartum: a systematic review and meta-analysis protocol.
Banaei M, Azizi M, Moridi A, Dashti S, Yabandeh AP, Roozbeh N
Syst Rev 2019 Jul 5;8(1):161. doi: 10.1186/s13643-019-1079-4. PMID: 31277721Free PMC Article
Incidence and Prevalence of Sexual Dysfunction in Women and Men: A Consensus Statement from the Fourth International Consultation on Sexual Medicine 2015.
McCabe MP, Sharlip ID, Lewis R, Atalla E, Balon R, Fisher AD, Laumann E, Lee SW, Segraves RT
J Sex Med 2016 Feb;13(2):144-52. doi: 10.1016/j.jsxm.2015.12.034. PMID: 26953829
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
Depression and sexuality.
Reynaert C, Zdanowicz N, Janne P, Jacques D
Psychiatr Danub 2010 Nov;22 Suppl 1:S111-3. PMID: 21057415
Retarded ejaculation.
Perelman MA, Rowland DL
World J Urol 2006 Dec;24(6):645-52. doi: 10.1007/s00345-006-0127-6. PMID: 17082938

Clinical prediction guides

Diagnosis and treatment of urinary and sexual dysfunction in hereditary TTR amyloidosis.
Bentellis I, Amarenco G, Gamé X, Jericevic D, El-Akri M, Voiry C, Freton L, Hascoet J, Alimi Q, Kerdraon J, Brucker BM, Peyronnet B
Clin Auton Res 2019 Sep;29(Suppl 1):65-74. Epub 2019 Aug 26 doi: 10.1007/s10286-019-00627-7. PMID: 31452024Free PMC Article
Sexual dysfunction and related factors in pregnancy and postpartum: a systematic review and meta-analysis protocol.
Banaei M, Azizi M, Moridi A, Dashti S, Yabandeh AP, Roozbeh N
Syst Rev 2019 Jul 5;8(1):161. doi: 10.1186/s13643-019-1079-4. PMID: 31277721Free PMC Article
Delayed orgasm and anorgasmia.
Jenkins LC, Mulhall JP
Fertil Steril 2015 Nov;104(5):1082-8. Epub 2015 Oct 9 doi: 10.1016/j.fertnstert.2015.09.029. PMID: 26439762Free PMC Article
An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction.
Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, Monga A, Petri E, Rizk DE, Sand PK, Schaer GN; International Urogynecological Association; International Continence Society
Neurourol Urodyn 2010;29(1):4-20. doi: 10.1002/nau.20798. PMID: 19941278
A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction.
Dording CM, Fisher L, Papakostas G, Farabaugh A, Sonawalla S, Fava M, Mischoulon D
CNS Neurosci Ther 2008 Fall;14(3):182-91. doi: 10.1111/j.1755-5949.2008.00052.x. PMID: 18801111Free PMC Article

Recent systematic reviews

Predictors for sexual dysfunction in the first year postpartum: A systematic review and meta-analysis.
Cattani L, De Maeyer L, Verbakel JY, Bosteels J, Deprest J
BJOG 2022 Jun;129(7):1017-1028. Epub 2021 Oct 17 doi: 10.1111/1471-0528.16934. PMID: 34536325
Vaginismus, Dyspareunia and Abuse History: A Systematic Review and Meta-analysis.
Tetik S, Yalçınkaya Alkar Ö
J Sex Med 2021 Sep;18(9):1555-1570. Epub 2021 Aug 6 doi: 10.1016/j.jsxm.2021.07.004. PMID: 34366265
European Association of Urology Guidelines on Sexual and Reproductive Health-2021 Update: Male Sexual Dysfunction.
Salonia A, Bettocchi C, Boeri L, Capogrosso P, Carvalho J, Cilesiz NC, Cocci A, Corona G, Dimitropoulos K, Gül M, Hatzichristodoulou G, Jones TH, Kadioglu A, Martínez Salamanca JI, Milenkovic U, Modgil V, Russo GI, Serefoglu EC, Tharakan T, Verze P, Minhas S; EAU Working Group on Male Sexual and Reproductive Health
Eur Urol 2021 Sep;80(3):333-357. Epub 2021 Jun 26 doi: 10.1016/j.eururo.2021.06.007. PMID: 34183196
INFERTILITY AND SEXUAL DYSFUNCTIONS: A SYSTEMATIC LITERATURE REVIEW.
Starc A, Trampuš M, Pavan Jukić D, Rotim C, Jukić T, Polona Mivšek A
Acta Clin Croat 2019 Sep;58(3):508-515. doi: 10.20471/acc.2019.58.03.15. PMID: 31969764Free PMC Article
Erectile Dysfunction: AUA Guideline.
Burnett AL, Nehra A, Breau RH, Culkin DJ, Faraday MM, Hakim LS, Heidelbaugh J, Khera M, McVary KT, Miner MM, Nelson CJ, Sadeghi-Nejad H, Seftel AD, Shindel AW
J Urol 2018 Sep;200(3):633-641. Epub 2018 May 7 doi: 10.1016/j.juro.2018.05.004. PMID: 29746858

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