U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pigmented Nevus

MedGen UID:
777118
•Concept ID:
C3665593
•
Neoplastic Process
Synonyms: Melanocytic nevi; Pigmented moles; Pigmented nevi; Pigmented nevus
SNOMED CT: Melanocytic nevus of skin (400010006); Pigmented nevus of skin (400010006); Mole of skin (400010006)

Definition

A nevus characterised by the presence of excessive pigment. [from NCI]

Professional guidelines

PubMed

The effect of carbon dioxide lattice laser cosmetic technique in the treatment of pigmented nevus and the evaluation of the improvement of patients' appearance.
Ye S, Zhou D
Minerva Surg 2022 Apr;77(2):195-197. Epub 2021 Aug 3 doi: 10.23736/S2724-5691.21.09041-9. PMID: 34342408
Clinical characteristics and treatment of 52 cases of phakomatosis pigmentovascularis.
Shin H, Kim YG, Kim YE, Park H
J Dermatol 2019 Oct;46(10):843-848. Epub 2019 Aug 6 doi: 10.1111/1346-8138.15035. PMID: 31389056
Diagnosis and treatment of pigmented moles and melanomas.
BECKER SW
Ill Med J 1954 Mar;105(3):113-8. PMID: 13128802

Recent clinical studies

Etiology

Care of Congenital Melanocytic Nevi in Newborns and Infants: Review and Management Recommendations.
Jahnke MN, O'Haver J, Gupta D, Hawryluk EB, Finelt N, Kruse L, Jen M, Horii KA, Frieden IJ, Price H, Coughlin CC
Pediatrics 2021 Dec 1;148(6) doi: 10.1542/peds.2021-051536. PMID: 34845496
Histologic mimics of malignant melanoma.
Bsirini C, Smoller BR
Singapore Med J 2018 Nov;59(11):602-607. Epub 2018 May 18 doi: 10.11622/smedj.2018041. PMID: 29774360Free PMC Article
Common and not so Common Melanocytic Lesions in Children and Adolescents.
Yang C, Gru AA, Dehner LP
Pediatr Dev Pathol 2018 Mar-Apr;21(2):252-270. doi: 10.1177/1093526617751720. PMID: 29607755
Dermal melanocytosis and associated disorders.
Franceschini D, Dinulos JG
Curr Opin Pediatr 2015 Aug;27(4):480-5. doi: 10.1097/MOP.0000000000000247. PMID: 26087431
Management of pigmented conjunctival lesions.
Oellers P, Karp CL
Ocul Surf 2012 Oct;10(4):251-63. Epub 2012 Aug 11 doi: 10.1016/j.jtos.2012.08.002. PMID: 23084146

Diagnosis

Phakomatosis Pigmentovascularis.
Tran C, Alward WLM
Ophthalmol Glaucoma 2021 May-Jun;4(3):250. doi: 10.1016/j.ogla.2021.03.003. PMID: 34030827
Kissing naevus.
Lysebo DE, Krohn J
Tidsskr Nor Laegeforen 2021 Jan 12;141(1) Epub 2021 Jan 7 doi: 10.4045/tidsskr.20.0605. PMID: 33433097
Melanocytic Nevi in Children: A Review.
Levy R, Lara-Corrales I
Pediatr Ann 2016 Aug 1;45(8):e293-8. doi: 10.3928/19382359-20160720-07. PMID: 27517357
Childhood melanoma.
Jen M, Murphy M, Grant-Kels JM
Clin Dermatol 2009 Nov-Dec;27(6):529-36. doi: 10.1016/j.clindermatol.2008.09.011. PMID: 19880040
Nevus spilus.
Vaidya DC, Schwartz RA, Janniger CK
Cutis 2007 Dec;80(6):465-8. PMID: 18246877

Therapy

Pigmented Lesions.
Ko E, Panchal N
Dermatol Clin 2020 Oct;38(4):485-494. doi: 10.1016/j.det.2020.05.009. PMID: 32892857
Drug-induced eruptive melanocytic nevi.
Vena GA, Fargnoli MC, Cassano N, Argenziano G
Expert Opin Drug Metab Toxicol 2017 Mar;13(3):293-300. Epub 2016 Oct 21 doi: 10.1080/17425255.2017.1247155. PMID: 27759434
Editorial.
Goldberg DJ
J Cosmet Laser Ther 2016 Aug;18(4):187. doi: 10.1080/14764172.2016.1200281. PMID: 27337367
Dermal melanocytosis and associated disorders.
Franceschini D, Dinulos JG
Curr Opin Pediatr 2015 Aug;27(4):480-5. doi: 10.1097/MOP.0000000000000247. PMID: 26087431
Angioadnexocentric nevus.
Hashimoto K, Amano M, Setoyama M
J Dermatol 2012 Nov;39(11):909-15. Epub 2012 Jul 4 doi: 10.1111/j.1346-8138.2012.01599.x. PMID: 22762690

Prognosis

Histologic mimics of malignant melanoma.
Bsirini C, Smoller BR
Singapore Med J 2018 Nov;59(11):602-607. Epub 2018 May 18 doi: 10.11622/smedj.2018041. PMID: 29774360Free PMC Article
Dermal melanocytosis and associated disorders.
Franceschini D, Dinulos JG
Curr Opin Pediatr 2015 Aug;27(4):480-5. doi: 10.1097/MOP.0000000000000247. PMID: 26087431
Management of pigmented conjunctival lesions.
Oellers P, Karp CL
Ocul Surf 2012 Oct;10(4):251-63. Epub 2012 Aug 11 doi: 10.1016/j.jtos.2012.08.002. PMID: 23084146
Melanocytic nevi.
Hauschild A, Egberts F, Garbe C, Bauer J, Grabbe S, Hamm H, Kerl H, Reusch M, Rompel R, Schlaeger M; expert group "Melanocytic nevi"
J Dtsch Dermatol Ges 2011 Sep;9(9):723-34. Epub 2011 Jul 15 doi: 10.1111/j.1610-0387.2011.07741.x. PMID: 21762380
Congenital melanocytic nevi.
Zayour M, Lazova R
Clin Lab Med 2011 Jun;31(2):267-80. doi: 10.1016/j.cll.2011.03.004. PMID: 21549240

Clinical prediction guides

Differentiating between early melanomas and melanocytic nevi: A state-of-the-art review.
Alsayyah A
Pathol Res Pract 2023 Sep;249:154734. Epub 2023 Aug 4 doi: 10.1016/j.prp.2023.154734. PMID: 37573619
Pigmented lesions of the conjunctiva: The sheep and the wolf.
Christy MC, Honavar SG, Mulay K, Talloju SS
Indian J Ophthalmol 2023 Jul;71(7):2927. doi: 10.4103/IJO.IJO_1367_23. PMID: 37417160Free PMC Article
ESP, EORTC, and EURACAN Expert Opinion: practical recommendations for the pathological diagnosis and clinical management of intermediate melanocytic tumors and rare related melanoma variants.
de la Fouchardiere A, Blokx W, van Kempen LC, Luzar B, Piperno-Neumann S, Puig S, Alos L, Calonje E, Massi D; ESP Dermatopathology Working Group; EORTC Melanoma Group; EURACAN
Virchows Arch 2021 Jul;479(1):3-11. Epub 2021 Jan 12 doi: 10.1007/s00428-020-03005-1. PMID: 33432480
Mucinous nevus.
Yokogawa M, Kamakura T, Ishiguro H, Ikeda M, Kodama H
J Dermatol 2005 Jan;32(1):30-3. doi: 10.1111/j.1346-8138.2005.tb00710.x. PMID: 15841658
Deep penetrating nevus.
Mehregan DA, Mehregan AH
Arch Dermatol 1993 Mar;129(3):328-31. PMID: 8447669

Recent systematic reviews

Changes in melanocytic nevi treated with laser hair removal: A systematic review.
Cices A, Dover JS, Labadie JG
Lasers Surg Med 2023 Sep;55(7):617-624. Epub 2023 Jul 26 doi: 10.1002/lsm.23712. PMID: 37493510
Safety and effectiveness of surgical excision of medium, large, and giant congenital melanocytic nevi: A systematic review and meta-analysis.
Gout HA, Fledderus AC, Lokhorst MM, Pasmans SGMA, Breugem CC, Lapid O, van der Horst CMAM
J Plast Reconstr Aesthet Surg 2023 Feb;77:430-455. Epub 2022 Nov 21 doi: 10.1016/j.bjps.2022.10.048. PMID: 36652871
Neurological signs, symptoms and MRI abnormalities in patients with congenital melanocytic naevi and evaluation of routine MRI-screening: systematic review and meta-analysis.
Fledderus AC, Widdershoven AL, Lapid O, Breugem CC, Pasmans SGMA, van der Horst CMAM, Engelen MM, Spuls PI
Orphanet J Rare Dis 2022 Mar 2;17(1):95. doi: 10.1186/s13023-022-02234-8. PMID: 35236387Free PMC Article
Divided nevus of the eyelid: review of embryology, pathology and treatment.
Desai SC, Walen S, Holds JB, Branham G
Am J Otolaryngol 2013 May-Jun;34(3):223-9. Epub 2013 Feb 4 doi: 10.1016/j.amjoto.2013.01.004. PMID: 23380310
Sunscreen use and melanocytic nevi in children: a systematic review.
de Maleissye MF, Beauchet A, Saiag P, Corrêa M, Godin-Beeckmann S, Haeffelin M, Mahé E
Pediatr Dermatol 2013 Jan-Feb;30(1):51-9. Epub 2012 Sep 20 doi: 10.1111/j.1525-1470.2012.01847.x. PMID: 22994908

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...