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Vascular ectasia

MedGen UID:: 8080
•Concept ID:: C0002959
•: Disease or Syndrome

Synonyms:	Angiectasia; Angiectasis; Angioectasia; Hemangiectasia; Hemangiectasis; Phlebarteriectasia; Vascular Ectasia; vascular ectasia
SNOMED CT:	Phlebarteriectasia (174637007); Angiectasia (174637007); Vascular ectasia (174637007); Angiectasis (174637007); Hemangiectasia (174637007); Hemangiectasis (174637007); Angioectasia (174637007)

Monarch Initiative:	MONDO:0021658

Definition

Dilatation of the blood vessels. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVVascular ectasia

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
- Congenital abnormality
  - Congenital Systemic Disorder
    - Congenital cardiovascular disorder
      - Congenital vascular malformation
        Vascular ectasia
        Angiokeratoma
        Angiokeratoma circumscriptum naeviforme
        Angiokeratoma of mibelli
        Fabry disease
        Fordyce angiokeratoma
        Skin Angiokeratoma
        Angiokeratoma circumscriptum
        Angiokeratoma of Fordyce
        Solitary angiokeratoma
        Vulvar angiokeratoma
        Coronary Artery Ectasia
        Lymphangiectasis
        Congenital pulmonary lymphangiectasia
        Intestinal lymphangiectasia
        Primary intestinal lymphangiectasia
        Protein-losing enteropathy
        Secondary intestinal lymphangiectasia
        Pancreatic lymphangiectasis
        Pericardial lymphangiectasia
        Pleural lymphangiectasia
        Pulmonary lymphangiectasia
        Thyroid lymphangiectasia
        Nevus anemicus
        Nevus flammeus
        Naevus flammeus of the eyelid
        Nevus flammeus nuchae
        Nevus flammeus of the forehead
        Spider telangiectasis of skin
        Acquired Nevus Araneus
        Congenital Nevus Araneus
        Telangiectasia
        Ataxia-telangiectasia syndrome
        CREST syndrome
        Cutis marmorata
        Diffuse telangiectasia
        Exudative retinopathy
        Hereditary hemorrhagic telangiectasia
        Hereditary hemorrhagic telangiectasia type 3
        Hereditary hemorrhagic telangiectasia type 4
        Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome
        Telangiectasia, hereditary hemorrhagic, type 1
        Telangiectasia, hereditary hemorrhagic, type 2
        Telangiectasia, hereditary hemorrhagic, type 5
        Mucosal telangiectasiae
        Bronchial telangiectasia
        Conjunctival telangiectasia
        Gastrointestinal telangiectasia
        Nasal mucosa telangiectasia
        Oral cavity telangiectasia
        Telangiectasia macularis eruptiva perstans
        Telangiectasia of the skin
        Facial telangiectasia
        Fingerpad telangiectases
        Palmar telangiectasia
        Periungual teleangiectasia
        Spider hemangioma
        Telangiectases producing 'marbled' skin
        Telangiectasia of extensor surfaces
        Telangiectasia of the ear
        Venous lake

Professional guidelines

PubMed

Pharmacotherapy for the Treatment of Gastric Antral Vascular Ectasia: A Narrative Review.

Peng M, Guo X, Yi F, Romeiro FG, Mancuso A, Qi X
Adv Ther 2021 Oct;38(10):5065-5077. Epub 2021 Sep 15 doi: 10.1007/s12325-021-01912-6. PMID: 34524644

Gastric vascular abnormalities: diagnosis and management.

Awadalla M, Mahmoud M, McNamara P, Wassef W
Curr Opin Gastroenterol 2020 Nov;36(6):538-546. doi: 10.1097/MOG.0000000000000675. PMID: 32925176

Review article: gastrointestinal angiodysplasia - pathogenesis, diagnosis and management.

Sami SS, Al-Araji SA, Ragunath K
Aliment Pharmacol Ther 2014 Jan;39(1):15-34. Epub 2013 Oct 20 doi: 10.1111/apt.12527. PMID: 24138285

See all (42)

Recent clinical studies

Etiology

Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers.

Cavazzana I, Vojinovic T, Airo' P, Fredi M, Ceribelli A, Pedretti E, Lazzaroni MG, Garrafa E, Franceschini F
Clin Rev Allergy Immunol 2023 Jun;64(3):412-430. Epub 2022 Jun 18 doi: 10.1007/s12016-022-08946-w. PMID: 35716254 Free PMC Article

Gastric antral vascular ectasia in systemic sclerosis: a study of its epidemiology, disease characteristics and impact on survival.

Morrisroe K, Hansen D, Stevens W, Sahhar J, Ngian GS, Hill C, Roddy J, Walker J, Proudman S, Nikpour M
Arthritis Res Ther 2022 May 10;24(1):103. doi: 10.1186/s13075-022-02790-1. PMID: 35538587 Free PMC Article

Pharmacotherapy for the Treatment of Gastric Antral Vascular Ectasia: A Narrative Review.

Peng M, Guo X, Yi F, Romeiro FG, Mancuso A, Qi X
Adv Ther 2021 Oct;38(10):5065-5077. Epub 2021 Sep 15 doi: 10.1007/s12325-021-01912-6. PMID: 34524644

Unusual Causes of Upper Gastrointestinal Bleeding.

Parikh K, Ali MA, Wong RC
Gastrointest Endosc Clin N Am 2015 Jul;25(3):583-605. Epub 2015 Apr 18 doi: 10.1016/j.giec.2015.02.009. PMID: 26142040

Gut-liver axis.

Zeuzem S
Int J Colorectal Dis 2000 Apr;15(2):59-82. doi: 10.1007/s003840050236. PMID: 10855547

See all (165)

Diagnosis

Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers.

Gastric vascular abnormalities: diagnosis and management.

Awadalla M, Mahmoud M, McNamara P, Wassef W
Curr Opin Gastroenterol 2020 Nov;36(6):538-546. doi: 10.1097/MOG.0000000000000675. PMID: 32925176

Portal hypertensive gastropathy and gastric antral vascular ectasia.

Garg H, Gupta S, Anand AC, Broor SL
Indian J Gastroenterol 2015 Sep;34(5):351-8. Epub 2015 Nov 13 doi: 10.1007/s12664-015-0605-0. PMID: 26564121

Review article: gastrointestinal angiodysplasia - pathogenesis, diagnosis and management.

Sami SS, Al-Araji SA, Ragunath K
Aliment Pharmacol Ther 2014 Jan;39(1):15-34. Epub 2013 Oct 20 doi: 10.1111/apt.12527. PMID: 24138285

The trigeminal nerve.

Nemzek WR
Top Magn Reson Imaging 1996 Jun;8(3):132-54. PMID: 8840469

See all (273)

Therapy

Gastric Antral Vascular Ectasia Pathogenesis and the Link to the Metabolic Syndrome.

Smith E, Davis J, Caldwell S
Curr Gastroenterol Rep 2018 Jul 2;20(8):36. doi: 10.1007/s11894-018-0644-7. PMID: 29961911

Vascular-targeted photodynamic therapy of gastric antral vascular ectasia (GAVE).

Qiu H, Mao Y, Zeng J, Wang Y, Zhang J, Huang N, Liu Q, Yang Y, Linghu E, Gu Y
J Photochem Photobiol B 2017 Jan;166:58-62. Epub 2016 Oct 29 doi: 10.1016/j.jphotobiol.2016.10.033. PMID: 27871022

Portal hypertensive gastropathy and gastric antral vascular ectasia.

Garg H, Gupta S, Anand AC, Broor SL
Indian J Gastroenterol 2015 Sep;34(5):351-8. Epub 2015 Nov 13 doi: 10.1007/s12664-015-0605-0. PMID: 26564121

Portal hypertensive gastropathy and gastric antral vascular ectasia.

Han S, Chaudhary N, Wassef W
Curr Opin Gastroenterol 2015 Nov;31(6):506-12. doi: 10.1097/MOG.0000000000000214. PMID: 26376475

Review article: gastrointestinal angiodysplasia - pathogenesis, diagnosis and management.

Sami SS, Al-Araji SA, Ragunath K
Aliment Pharmacol Ther 2014 Jan;39(1):15-34. Epub 2013 Oct 20 doi: 10.1111/apt.12527. PMID: 24138285

See all (144)

Prognosis

Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers.

An update on biomarker discovery and use in systemic sclerosis.

Matsushita T, Takehara K
Expert Rev Mol Diagn 2017 Sep;17(9):823-833. Epub 2017 Jul 25 doi: 10.1080/14737159.2017.1356722. PMID: 28730919

Gastric antral vascular ectasia in systemic sclerosis: Where do we stand?

El-Gendy H, Shohdy KS, Maghraby GG, Abadeer K, Mahmoud M
Int J Rheum Dis 2017 Dec;20(12):2133-2139. Epub 2017 Feb 20 doi: 10.1111/1756-185X.13047. PMID: 28217887

Epidemiology of lower gastrointestinal bleeding.

Zuccaro G
Best Pract Res Clin Gastroenterol 2008;22(2):225-32. doi: 10.1016/j.bpg.2007.10.009. PMID: 18346680

The trigeminal nerve.

Nemzek WR
Top Magn Reson Imaging 1996 Jun;8(3):132-54. PMID: 8840469

See all (98)

Clinical prediction guides

Systemic Sclerosis-Specific Antibodies: Novel and Classical Biomarkers.

An update on biomarker discovery and use in systemic sclerosis.

Matsushita T, Takehara K
Expert Rev Mol Diagn 2017 Sep;17(9):823-833. Epub 2017 Jul 25 doi: 10.1080/14737159.2017.1356722. PMID: 28730919

Portal hypertensive gastropathy and gastric antral vascular ectasia.

Garg H, Gupta S, Anand AC, Broor SL
Indian J Gastroenterol 2015 Sep;34(5):351-8. Epub 2015 Nov 13 doi: 10.1007/s12664-015-0605-0. PMID: 26564121

Gut-liver axis.

Zeuzem S
Int J Colorectal Dis 2000 Apr;15(2):59-82. doi: 10.1007/s003840050236. PMID: 10855547

The trigeminal nerve.

Nemzek WR
Top Magn Reson Imaging 1996 Jun;8(3):132-54. PMID: 8840469

See all (97)

Recent systematic reviews

Endoscopic band ligation in the treatment of gastric antral vascular ectasia: a systematic review and meta-analysis.

Mohan BP, Toy G, Kassab LL, Ponnada S, Chandan S, Parbhu S, Chandna S, Adler DG
Gastrointest Endosc 2021 Dec;94(6):1021-1029.e10. Epub 2021 Sep 1 doi: 10.1016/j.gie.2021.08.017. PMID: 34480922

Endoscopic band ligation compared to thermal therapy for gastric antral vascular ectasia: A systematic review and meta-analysis.

Chalhoub JM, Umar J, Groudan K, Hamadeh N, Desilets DJ, Greeff Y
United European Gastroenterol J 2021 Mar;9(2):150-158. Epub 2021 Feb 18 doi: 10.1177/2050640620975243. PMID: 33210983 Free PMC Article

Comparative Effectiveness and Safety of Radiofrequency Ablation Versus Argon Plasma Coagulation for Treatment of Gastric Antral Vascular Ectasia: A Systematic Review and Meta-Analysis.

McCarty TR, Rustagi T
J Clin Gastroenterol 2019 Sep;53(8):599-606. doi: 10.1097/MCG.0000000000001088. PMID: 29952856

Medical and endoscopic therapies for angiodysplasia and gastric antral vascular ectasia: a systematic review.

Swanson E, Mahgoub A, MacDonald R, Shaukat A
Clin Gastroenterol Hepatol 2014 Apr;12(4):571-82. Epub 2013 Sep 5 doi: 10.1016/j.cgh.2013.08.038. PMID: 24013107

See all (4)

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Vascular ectasia

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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