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Benign Ovarian Epithelial Tumor

MedGen UID:
83411
•Concept ID:
C0346168
•
Neoplastic Process
Synonyms: Benign Epithelial Neoplasm of Ovary; Benign Epithelial Neoplasm of the Ovary; Benign epithelial tumor of ovary; Benign Epithelial Tumor of Ovary; Benign Epithelial Tumor of the Ovary; Benign Ovarian Epithelial Neoplasm; Benign Ovarian Surface Epithelial Neoplasm; Benign Ovarian Surface Epithelial Tumor; Benign Ovarian Surface Epithelial-Stromal Tumor; Benign Surface Epithelial Neoplasm of Ovary; Benign Surface Epithelial Neoplasm of the Ovary; Benign Surface Epithelial Tumor of Ovary; Benign Surface Epithelial Tumor of the Ovary
SNOMED CT: Benign epithelial tumor of ovary (254857008)

Definition

A neoplasm that arises from the surface epithelium of the ovary and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include serous cystadenoma, mucinous cystadenoma, clear cell adenofibroma, and benign Brenner tumor. [from NCI]

Professional guidelines

PubMed

OvaPrint-A Cell-free DNA Methylation Liquid Biopsy for the Risk Assessment of High-grade Serous Ovarian Cancer.
Buckley DN, Lewinger JP, Gooden G, Spillman M, Neuman M, Guo XM, Tew BY, Miller H, Khetan VU, Shulman LP, Roman L, Salhia B
Clin Cancer Res 2023 Dec 15;29(24):5196-5206. doi: 10.1158/1078-0432.CCR-23-1197. PMID: 37812492Free PMC Article
Guidelines for Pathologic Diagnosis of Malignant Mesothelioma 2017 Update of the Consensus Statement From the International Mesothelioma Interest Group.
Husain AN, Colby TV, Ordóñez NG, Allen TC, Attanoos RL, Beasley MB, Butnor KJ, Chirieac LR, Churg AM, Dacic S, Galateau-Sallé F, Gibbs A, Gown AM, Krausz T, Litzky LA, Marchevsky A, Nicholson AG, Roggli VL, Sharma AK, Travis WD, Walts AE, Wick MR
Arch Pathol Lab Med 2018 Jan;142(1):89-108. Epub 2017 Jul 7 doi: 10.5858/arpa.2017-0124-RA. PMID: 28686500
Ovarian borderline tumors in the 2014 WHO classification: evolving concepts and diagnostic criteria.
Hauptmann S, Friedrich K, Redline R, Avril S
Virchows Arch 2017 Feb;470(2):125-142. Epub 2016 Dec 27 doi: 10.1007/s00428-016-2040-8. PMID: 28025670Free PMC Article

Recent clinical studies

Etiology

ELF5 in epithelial ovarian carcinoma tissues and biological behavior in ovarian carcinoma cells.
Yan H, Qiu L, Xie X, Yang H, Liu Y, Lin X, Huang H
Oncol Rep 2017 Mar;37(3):1412-1418. Epub 2017 Feb 2 doi: 10.3892/or.2017.5418. PMID: 28184931Free PMC Article
Expression of hMOF in different ovarian tissues and its effects on ovarian cancer prognosis.
Cai M, Hu Z, Liu J, Gao J, Tan M, Zhang D, Zhu L, Liu S, Hou R, Lin B
Oncol Rep 2015 Feb;33(2):685-92. Epub 2014 Dec 5 doi: 10.3892/or.2014.3649. PMID: 25483274

Diagnosis

Protein expressions of AIB1, p53 and Bcl-2 in epithelial ovarian cancer and their correlations with the clinical pathological features and prognosis.
Liang M, Zhao J
Eur Rev Med Pharmacol Sci 2018 Aug;22(16):5134-5139. doi: 10.26355/eurrev_201808_15708. PMID: 30178833

Prognosis

Protein expressions of AIB1, p53 and Bcl-2 in epithelial ovarian cancer and their correlations with the clinical pathological features and prognosis.
Liang M, Zhao J
Eur Rev Med Pharmacol Sci 2018 Aug;22(16):5134-5139. doi: 10.26355/eurrev_201808_15708. PMID: 30178833
ELF5 in epithelial ovarian carcinoma tissues and biological behavior in ovarian carcinoma cells.
Yan H, Qiu L, Xie X, Yang H, Liu Y, Lin X, Huang H
Oncol Rep 2017 Mar;37(3):1412-1418. Epub 2017 Feb 2 doi: 10.3892/or.2017.5418. PMID: 28184931Free PMC Article
Nedd4L expression is decreased in ovarian epithelial cancer tissues compared to ovarian non-cancer tissue.
Yang Q, Zhao J, Cui M, Gi S, Wang W, Han X
J Obstet Gynaecol Res 2015 Dec;41(12):1959-64. Epub 2015 Nov 10 doi: 10.1111/jog.12808. PMID: 26554540
Expression of hMOF in different ovarian tissues and its effects on ovarian cancer prognosis.
Cai M, Hu Z, Liu J, Gao J, Tan M, Zhang D, Zhu L, Liu S, Hou R, Lin B
Oncol Rep 2015 Feb;33(2):685-92. Epub 2014 Dec 5 doi: 10.3892/or.2014.3649. PMID: 25483274

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