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Hearing loss

MedGen UID:
854601
•Concept ID:
C3887873
•
Finding
Synonym: Hearing Loss

Definition

A partial or complete loss of hearing in one or both ears. It is classified as conductive, sensory, or central. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Professional guidelines

PubMed

Clinical Practice Guideline: Sudden Hearing Loss (Update).
Chandrasekhar SS, Tsai Do BS, Schwartz SR, Bontempo LJ, Faucett EA, Finestone SA, Hollingsworth DB, Kelley DM, Kmucha ST, Moonis G, Poling GL, Roberts JK, Stachler RJ, Zeitler DM, Corrigan MD, Nnacheta LC, Satterfield L
Otolaryngol Head Neck Surg 2019 Aug;161(1_suppl):S1-S45. doi: 10.1177/0194599819859885. PMID: 31369359
Hearing Loss in Adults: Differential Diagnosis and Treatment.
Michels TC, Duffy MT, Rogers DJ
Am Fam Physician 2019 Jul 15;100(2):98-108. PMID: 31305044
Otitis media: diagnosis and treatment.
Harmes KM, Blackwood RA, Burrows HL, Cooke JM, Harrison RV, Passamani PP
Am Fam Physician 2013 Oct 1;88(7):435-40. PMID: 24134083

Curated

UK NICE Guideline (NG98), Hearing loss in adults: assessment and management, 2023

American College of Medical Genetics ACT SHEET, Newborn Screening ACT Sheet Algorithm, Congenital Hearing Loss, 2009

Recent clinical studies

Etiology

Diabetes mellitus and hearing loss: A review.
Samocha-Bonet D, Wu B, Ryugo DK
Ageing Res Rev 2021 Nov;71:101423. Epub 2021 Aug 9 doi: 10.1016/j.arr.2021.101423. PMID: 34384902
Hearing Loss.
Nieman CL, Oh ES
Ann Intern Med 2020 Dec 1;173(11):ITC81-ITC96. doi: 10.7326/AITC202012010. PMID: 33253610
Hearing Loss, Loneliness, and Social Isolation: A Systematic Review.
Shukla A, Harper M, Pedersen E, Goman A, Suen JJ, Price C, Applebaum J, Hoyer M, Lin FR, Reed NS
Otolaryngol Head Neck Surg 2020 May;162(5):622-633. Epub 2020 Mar 10 doi: 10.1177/0194599820910377. PMID: 32151193Free PMC Article
Clinical Practice Guideline: Sudden Hearing Loss (Update).
Chandrasekhar SS, Tsai Do BS, Schwartz SR, Bontempo LJ, Faucett EA, Finestone SA, Hollingsworth DB, Kelley DM, Kmucha ST, Moonis G, Poling GL, Roberts JK, Stachler RJ, Zeitler DM, Corrigan MD, Nnacheta LC, Satterfield L
Otolaryngol Head Neck Surg 2019 Aug;161(1_suppl):S1-S45. doi: 10.1177/0194599819859885. PMID: 31369359
Hearing loss: diagnosis and management.
Lasak JM, Allen P, McVay T, Lewis D
Prim Care 2014 Mar;41(1):19-31. Epub 2013 Nov 18 doi: 10.1016/j.pop.2013.10.003. PMID: 24439878

Diagnosis

Congenital Sensorineural Hearing Loss.
Shave S, Botti C, Kwong K
Pediatr Clin North Am 2022 Apr;69(2):221-234. doi: 10.1016/j.pcl.2021.12.006. PMID: 35337535
Hearing Loss.
Nieman CL, Oh ES
Ann Intern Med 2020 Dec 1;173(11):ITC81-ITC96. doi: 10.7326/AITC202012010. PMID: 33253610
Clinical Practice Guideline: Sudden Hearing Loss (Update).
Chandrasekhar SS, Tsai Do BS, Schwartz SR, Bontempo LJ, Faucett EA, Finestone SA, Hollingsworth DB, Kelley DM, Kmucha ST, Moonis G, Poling GL, Roberts JK, Stachler RJ, Zeitler DM, Corrigan MD, Nnacheta LC, Satterfield L
Otolaryngol Head Neck Surg 2019 Aug;161(1_suppl):S1-S45. doi: 10.1177/0194599819859885. PMID: 31369359
Hearing Loss in Adults: Differential Diagnosis and Treatment.
Michels TC, Duffy MT, Rogers DJ
Am Fam Physician 2019 Jul 15;100(2):98-108. PMID: 31305044
Hearing loss: diagnosis and management.
Lasak JM, Allen P, McVay T, Lewis D
Prim Care 2014 Mar;41(1):19-31. Epub 2013 Nov 18 doi: 10.1016/j.pop.2013.10.003. PMID: 24439878

Therapy

Hyperbaric Oxygen Therapy for Patients With Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-analysis.
Joshua TG, Ayub A, Wijesinghe P, Nunez DA
JAMA Otolaryngol Head Neck Surg 2022 Jan 1;148(1):5-11. doi: 10.1001/jamaoto.2021.2685. PMID: 34709348Free PMC Article
Noise-Induced Hearing Loss: Updates on Molecular Targets and Potential Interventions.
Mao H, Chen Y
Neural Plast 2021;2021:4784385. Epub 2021 Jul 6 doi: 10.1155/2021/4784385. PMID: 34306060Free PMC Article
Gene therapy for hearing loss.
Omichi R, Shibata SB, Morton CC, Smith RJH
Hum Mol Genet 2019 Oct 1;28(R1):R65-R79. doi: 10.1093/hmg/ddz129. PMID: 31227837Free PMC Article
Advances in Understanding, Diagnosis, and Treatment of Tinnitus.
Tang D, Li H, Chen L
Adv Exp Med Biol 2019;1130:109-128. doi: 10.1007/978-981-13-6123-4_7. PMID: 30915704
Corticosteroids for acute bacterial meningitis.
Brouwer MC, McIntyre P, Prasad K, van de Beek D
Cochrane Database Syst Rev 2015 Sep 12;2015(9):CD004405. doi: 10.1002/14651858.CD004405.pub5. PMID: 26362566Free PMC Article

Prognosis

Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss.
Brock PR, Maibach R, Childs M, Rajput K, Roebuck D, Sullivan MJ, Laithier V, Ronghe M, Dall'Igna P, Hiyama E, Brichard B, Skeen J, Mateos ME, Capra M, Rangaswami AA, Ansari M, Rechnitzer C, Veal GJ, Covezzoli A, Brugières L, Perilongo G, Czauderna P, Morland B, Neuwelt EA
N Engl J Med 2018 Jun 21;378(25):2376-2385. doi: 10.1056/NEJMoa1801109. PMID: 29924955Free PMC Article
Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
GBD 2016 Disease and Injury Incidence and Prevalence Collaborators
Lancet 2017 Sep 16;390(10100):1211-1259. doi: 10.1016/S0140-6736(17)32154-2. PMID: 28919117Free PMC Article
Congenital Cytomegalovirus infection: advances and challenges in diagnosis, prevention and treatment.
Marsico C, Kimberlin DW
Ital J Pediatr 2017 Apr 17;43(1):38. doi: 10.1186/s13052-017-0358-8. PMID: 28416012Free PMC Article
Aging and Hearing Health: The Life-course Approach.
Davis A, McMahon CM, Pichora-Fuller KM, Russ S, Lin F, Olusanya BO, Chadha S, Tremblay KL
Gerontologist 2016 Apr;56 Suppl 2(Suppl 2):S256-67. doi: 10.1093/geront/gnw033. PMID: 26994265Free PMC Article
Hearing loss and incident dementia.
Lin FR, Metter EJ, O'Brien RJ, Resnick SM, Zonderman AB, Ferrucci L
Arch Neurol 2011 Feb;68(2):214-20. doi: 10.1001/archneurol.2010.362. PMID: 21320988Free PMC Article

Clinical prediction guides

Implications and attitudes of audiologists towards smartphone integration in hearing healthcare.
Kimball SH, Singh G, John AB, Jenstad LM
Hear Res 2018 Nov;369:15-23. Epub 2018 Jun 19 doi: 10.1016/j.heares.2018.06.011. PMID: 29945802
Monitoring neonates for ototoxicity.
Garinis AC, Kemph A, Tharpe AM, Weitkamp JH, McEvoy C, Steyger PS
Int J Audiol 2018 Sep;57(sup4):S41-S48. Epub 2017 Jun 22 doi: 10.1080/14992027.2017.1339130. PMID: 28949262Free PMC Article
Prediction of conductive hearing loss using wideband acoustic immittance.
Prieve BA, Feeney MP, Stenfelt S, Shahnaz N
Ear Hear 2013 Jul;34 Suppl 1:54S-59S. doi: 10.1097/AUD.0b013e31829c9670. PMID: 23900182
Predicting binaural interference.
Jerger J
J Am Acad Audiol 2011 Mar;22(3):128. doi: 10.3766/jaaa.22.3.1. PMID: 21545765
Universal newborn hearing screening.
Wrightson AS
Am Fam Physician 2007 May 1;75(9):1349-52. PMID: 17508530

Recent systematic reviews

Hyperbaric Oxygen Therapy for Patients With Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-analysis.
Joshua TG, Ayub A, Wijesinghe P, Nunez DA
JAMA Otolaryngol Head Neck Surg 2022 Jan 1;148(1):5-11. doi: 10.1001/jamaoto.2021.2685. PMID: 34709348Free PMC Article
Hearing Loss, Tinnitus, and Dizziness in COVID-19: A Systematic Review and Meta-Analysis.
Jafari Z, Kolb BE, Mohajerani MH
Can J Neurol Sci 2022 Mar;49(2):184-195. Epub 2021 Apr 12 doi: 10.1017/cjn.2021.63. PMID: 33843530Free PMC Article
Hearing loss prevalence and years lived with disability, 1990-2019: findings from the Global Burden of Disease Study 2019.
GBD 2019 Hearing Loss Collaborators
Lancet 2021 Mar 13;397(10278):996-1009. doi: 10.1016/S0140-6736(21)00516-X. PMID: 33714390Free PMC Article
Hearing Loss, Loneliness, and Social Isolation: A Systematic Review.
Shukla A, Harper M, Pedersen E, Goman A, Suen JJ, Price C, Applebaum J, Hoyer M, Lin FR, Reed NS
Otolaryngol Head Neck Surg 2020 May;162(5):622-633. Epub 2020 Mar 10 doi: 10.1177/0194599820910377. PMID: 32151193Free PMC Article
Occupational noise exposure and hearing: a systematic review.
Lie A, Skogstad M, Johannessen HA, Tynes T, Mehlum IS, Nordby KC, Engdahl B, Tambs K
Int Arch Occup Environ Health 2016 Apr;89(3):351-72. Epub 2015 Aug 7 doi: 10.1007/s00420-015-1083-5. PMID: 26249711Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2023
      UK NICE Guideline (NG98), Hearing loss in adults: assessment and management, 2023
    • ACMG Algorithm, 2009
      American College of Medical Genetics ACT SHEET, Newborn Screening ACT Sheet Algorithm, Congenital Hearing Loss, 2009

    Consumer resources

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

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