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Paraplegia/paraparesis

MedGen UID:
869366
•Concept ID:
C4023792
•
Disease or Syndrome
HPO: HP:0010551

Definition

Weakness of both lower extremities with sparing of the upper extremities. Paraplegia refers to a severe or complete loss of strength, whereas paraparesis refers to a relatively mild loss of strength. [from HPO]

Professional guidelines

PubMed

Systematic review and meta-analysis of current evidence in endograft therapy vs medical treatment for uncomplicated type B aortic dissection.
Wang J, Jin T, Chen B, Pan Y, Shao C
J Vasc Surg 2022 Oct;76(4):1099-1108.e3. Epub 2022 Apr 4 doi: 10.1016/j.jvs.2022.03.876. PMID: 35390485
Evidence-based guideline update: intraoperative spinal monitoring with somatosensory and transcranial electrical motor evoked potentials*.
Nuwer MR, Emerson RG, Galloway G, Legatt AD, Lopez J, Minahan R, Yamada T, Goodin DS, Armon C, Chaudhry V, Gronseth GS, Harden CL; American Association of Neuromuscular and Electrodiagnostic Medicine
J Clin Neurophysiol 2012 Feb;29(1):101-8. doi: 10.1097/WNP.0b013e31824a397e. PMID: 22353994
Evidence-based guideline update: intraoperative spinal monitoring with somatosensory and transcranial electrical motor evoked potentials: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the American Clinical Neurophysiology Society.
Nuwer MR, Emerson RG, Galloway G, Legatt AD, Lopez J, Minahan R, Yamada T, Goodin DS, Armon C, Chaudhry V, Gronseth GS, Harden CL; Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology; American Clinical Neurophysiology Society
Neurology 2012 Feb 21;78(8):585-9. doi: 10.1212/WNL.0b013e318247fa0e. PMID: 22351796

Recent clinical studies

Etiology

Outcomes After Extent I Thoracoabdominal Aortic Repair: Focus on Heritable Aortic Disease.
Rebello KR, Green SY, Etheridge GM, Zhang Q, Glover VA, Zea-Vera R, Moon MR, LeMaire SA, Coselli JS
Ann Thorac Surg 2024 Feb;117(2):328-335. Epub 2023 Oct 21 doi: 10.1016/j.athoracsur.2023.10.012. PMID: 37866646
Endovascular versus conventional open surgical repair for thoracoabdominal aortic aneurysms.
Sultan S, Concannon J, Veerasingam D, Tawfick W, McHugh P, Jordan F, Hynes N
Cochrane Database Syst Rev 2022 Apr 1;4(4):CD012926. doi: 10.1002/14651858.CD012926.pub2. PMID: 35363887Free PMC Article
Hybrid Surgery to Manage Aortic Arch Pathology.
Gelpi G, Romagnoni C, Epifani F, Contino M, Antona C
Medicina (Kaunas) 2021 Aug 30;57(9) doi: 10.3390/medicina57090909. PMID: 34577832Free PMC Article
Neuraxial and peripheral misconnection events leading to wrong-route medication errors: a comprehensive literature review.
Viscusi ER, Hugo V, Hoerauf K, Southwick FS
Reg Anesth Pain Med 2021 Feb;46(2):176-181. Epub 2020 Nov 3 doi: 10.1136/rapm-2020-101836. PMID: 33144409Free PMC Article
Surfer's myelopathy.
Thompson TP, Pearce J, Chang G, Madamba J
Spine (Phila Pa 1976) 2004 Aug 15;29(16):E353-6. doi: 10.1097/01.brs.0000134689.84162.e7. PMID: 15303045

Diagnosis

Urgent Thoracic Endovascular Aortic Repair for Type-B(0,D) Acute Aortic Dissection.
Hari Y, Takagi H
Ann Vasc Surg 2024 Dec;109:1-8. Epub 2024 Jul 16 doi: 10.1016/j.avsg.2024.05.025. PMID: 39025222
Outcomes After Extent I Thoracoabdominal Aortic Repair: Focus on Heritable Aortic Disease.
Rebello KR, Green SY, Etheridge GM, Zhang Q, Glover VA, Zea-Vera R, Moon MR, LeMaire SA, Coselli JS
Ann Thorac Surg 2024 Feb;117(2):328-335. Epub 2023 Oct 21 doi: 10.1016/j.athoracsur.2023.10.012. PMID: 37866646
One-Year Results of a Low-Profile Endograft in Acute, Complicated Type B Aortic Dissection.
Rossi PJ, Desai ND, Malaisrie SC, Lyden SP, Nassiri N, Reece TB, Adams JD, Moanie SL, Shults CC; RelayPro-D Investigators
Ann Thorac Surg 2024 Feb;117(2):336-343. Epub 2023 Sep 27 doi: 10.1016/j.athoracsur.2023.08.035. PMID: 37769702
Ischemic Spinal Cord Injury-Experimental Evidence and Evolution of Protective Measures.
Khachatryan Z, Haunschild J, von Aspern K, Borger MA, Etz CD
Ann Thorac Surg 2022 May;113(5):1692-1702. Epub 2021 Jan 9 doi: 10.1016/j.athoracsur.2020.12.028. PMID: 33434541
Surfer's myelopathy.
Thompson TP, Pearce J, Chang G, Madamba J
Spine (Phila Pa 1976) 2004 Aug 15;29(16):E353-6. doi: 10.1097/01.brs.0000134689.84162.e7. PMID: 15303045

Therapy

Urgent Thoracic Endovascular Aortic Repair for Type-B(0,D) Acute Aortic Dissection.
Hari Y, Takagi H
Ann Vasc Surg 2024 Dec;109:1-8. Epub 2024 Jul 16 doi: 10.1016/j.avsg.2024.05.025. PMID: 39025222
Outcomes After Extent I Thoracoabdominal Aortic Repair: Focus on Heritable Aortic Disease.
Rebello KR, Green SY, Etheridge GM, Zhang Q, Glover VA, Zea-Vera R, Moon MR, LeMaire SA, Coselli JS
Ann Thorac Surg 2024 Feb;117(2):328-335. Epub 2023 Oct 21 doi: 10.1016/j.athoracsur.2023.10.012. PMID: 37866646
Systematic review and meta-analysis of current evidence in endograft therapy vs medical treatment for uncomplicated type B aortic dissection.
Wang J, Jin T, Chen B, Pan Y, Shao C
J Vasc Surg 2022 Oct;76(4):1099-1108.e3. Epub 2022 Apr 4 doi: 10.1016/j.jvs.2022.03.876. PMID: 35390485
Endovascular versus conventional open surgical repair for thoracoabdominal aortic aneurysms.
Sultan S, Concannon J, Veerasingam D, Tawfick W, McHugh P, Jordan F, Hynes N
Cochrane Database Syst Rev 2022 Apr 1;4(4):CD012926. doi: 10.1002/14651858.CD012926.pub2. PMID: 35363887Free PMC Article
Outcomes of 3309 thoracoabdominal aortic aneurysm repairs.
Coselli JS, LeMaire SA, Preventza O, de la Cruz KI, Cooley DA, Price MD, Stolz AP, Green SY, Arredondo CN, Rosengart TK
J Thorac Cardiovasc Surg 2016 May;151(5):1323-37. Epub 2016 Jan 14 doi: 10.1016/j.jtcvs.2015.12.050. PMID: 26898979

Prognosis

Outcomes After Extent I Thoracoabdominal Aortic Repair: Focus on Heritable Aortic Disease.
Rebello KR, Green SY, Etheridge GM, Zhang Q, Glover VA, Zea-Vera R, Moon MR, LeMaire SA, Coselli JS
Ann Thorac Surg 2024 Feb;117(2):328-335. Epub 2023 Oct 21 doi: 10.1016/j.athoracsur.2023.10.012. PMID: 37866646
Systematic review and meta-analysis of current evidence in endograft therapy vs medical treatment for uncomplicated type B aortic dissection.
Wang J, Jin T, Chen B, Pan Y, Shao C
J Vasc Surg 2022 Oct;76(4):1099-1108.e3. Epub 2022 Apr 4 doi: 10.1016/j.jvs.2022.03.876. PMID: 35390485
Early Gastrointestinal Complications After Open Thoracoabdominal Aortic Aneurysm Repair.
Frankel WC, Green SY, Amarasekara HS, Zhang Q, Preventza O, LeMaire SA, Coselli JS
Ann Thorac Surg 2021 Sep;112(3):717-724. Epub 2020 Nov 18 doi: 10.1016/j.athoracsur.2020.09.032. PMID: 33217404
Open Descending and Thoracoabdominal Aortic Repairs in Patients Younger Than 50 Years Old.
Tanaka A, Leonard SD, Sandhu HK, Afifi RO, Miller CC 3rd, Charlton-Ouw KM, Ray A, Hassan M, Safi HJ, Estrera AL
Ann Thorac Surg 2019 Sep;108(3):693-699. Epub 2019 Apr 19 doi: 10.1016/j.athoracsur.2019.03.058. PMID: 31009630
Outcomes of 3309 thoracoabdominal aortic aneurysm repairs.
Coselli JS, LeMaire SA, Preventza O, de la Cruz KI, Cooley DA, Price MD, Stolz AP, Green SY, Arredondo CN, Rosengart TK
J Thorac Cardiovasc Surg 2016 May;151(5):1323-37. Epub 2016 Jan 14 doi: 10.1016/j.jtcvs.2015.12.050. PMID: 26898979

Clinical prediction guides

Outcomes After Extent I Thoracoabdominal Aortic Repair: Focus on Heritable Aortic Disease.
Rebello KR, Green SY, Etheridge GM, Zhang Q, Glover VA, Zea-Vera R, Moon MR, LeMaire SA, Coselli JS
Ann Thorac Surg 2024 Feb;117(2):328-335. Epub 2023 Oct 21 doi: 10.1016/j.athoracsur.2023.10.012. PMID: 37866646
Systematic review and meta-analysis of current evidence in endograft therapy vs medical treatment for uncomplicated type B aortic dissection.
Wang J, Jin T, Chen B, Pan Y, Shao C
J Vasc Surg 2022 Oct;76(4):1099-1108.e3. Epub 2022 Apr 4 doi: 10.1016/j.jvs.2022.03.876. PMID: 35390485
Early Gastrointestinal Complications After Open Thoracoabdominal Aortic Aneurysm Repair.
Frankel WC, Green SY, Amarasekara HS, Zhang Q, Preventza O, LeMaire SA, Coselli JS
Ann Thorac Surg 2021 Sep;112(3):717-724. Epub 2020 Nov 18 doi: 10.1016/j.athoracsur.2020.09.032. PMID: 33217404
Open Descending and Thoracoabdominal Aortic Repairs in Patients Younger Than 50 Years Old.
Tanaka A, Leonard SD, Sandhu HK, Afifi RO, Miller CC 3rd, Charlton-Ouw KM, Ray A, Hassan M, Safi HJ, Estrera AL
Ann Thorac Surg 2019 Sep;108(3):693-699. Epub 2019 Apr 19 doi: 10.1016/j.athoracsur.2019.03.058. PMID: 31009630
Outcome of patients with open and endovascular repair in acute complicated type B aortic dissection: a systematic review and meta-analysis of case series and comparative studies.
Luebke T, Brunkwall J
J Cardiovasc Surg (Torino) 2010 Oct;51(5):613-32. PMID: 20924323

Recent systematic reviews

Systematic review and meta-analysis of current evidence in endograft therapy vs medical treatment for uncomplicated type B aortic dissection.
Wang J, Jin T, Chen B, Pan Y, Shao C
J Vasc Surg 2022 Oct;76(4):1099-1108.e3. Epub 2022 Apr 4 doi: 10.1016/j.jvs.2022.03.876. PMID: 35390485
Endovascular versus conventional open surgical repair for thoracoabdominal aortic aneurysms.
Sultan S, Concannon J, Veerasingam D, Tawfick W, McHugh P, Jordan F, Hynes N
Cochrane Database Syst Rev 2022 Apr 1;4(4):CD012926. doi: 10.1002/14651858.CD012926.pub2. PMID: 35363887Free PMC Article
Outcome of patients with open and endovascular repair in acute complicated type B aortic dissection: a systematic review and meta-analysis of case series and comparative studies.
Luebke T, Brunkwall J
J Cardiovasc Surg (Torino) 2010 Oct;51(5):613-32. PMID: 20924323

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