U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal gastric mucosa morphology

MedGen UID:
870900
•Concept ID:
C4025362
•
Anatomical Abnormality
Synonyms: Abnormality of the gastric mucosa; Abnormality of the mucous membrane layer of stomach
 
HPO: HP:0004295

Definition

An abnormality of the gastric mucous membrane. [from HPO]

Professional guidelines

PubMed

AGA Clinical Practice Update on Endoscopic Treatment of Barrett's Esophagus With Dysplasia and/or Early Cancer: Expert Review.
Sharma P, Shaheen NJ, Katzka D, Bergman JJGHM
Gastroenterology 2020 Feb;158(3):760-769. Epub 2019 Nov 12 doi: 10.1053/j.gastro.2019.09.051. PMID: 31730766
Diagnosis and treatment of gastric antral webs in pediatric patients.
Amin R, Martinez AM, Arca MJ
Surg Endosc 2019 Mar;33(3):745-749. Epub 2018 Jul 13 doi: 10.1007/s00464-018-6338-2. PMID: 30006842
Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management.
Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A
J Formos Med Assoc 2018 Sep;117(9):756-765. Epub 2018 Feb 19 doi: 10.1016/j.jfma.2018.01.021. PMID: 29472048

Recent clinical studies

Etiology

Helicobacter pylori-induced RASAL2 Through Activation of Nuclear Factor-κB Promotes Gastric Tumorigenesis via β-catenin Signaling Axis.
Cao L, Zhu S, Lu H, Soutto M, Bhat N, Chen Z, Peng D, Lin J, Lu J, Li P, Zheng C, Huang C, El-Rifai W
Gastroenterology 2022 May;162(6):1716-1731.e17. Epub 2022 Feb 5 doi: 10.1053/j.gastro.2022.01.046. PMID: 35134322Free PMC Article
AGA Clinical Practice Update on Endoscopic Treatment of Barrett's Esophagus With Dysplasia and/or Early Cancer: Expert Review.
Sharma P, Shaheen NJ, Katzka D, Bergman JJGHM
Gastroenterology 2020 Feb;158(3):760-769. Epub 2019 Nov 12 doi: 10.1053/j.gastro.2019.09.051. PMID: 31730766
Clinical manifestations of chronic atrophic gastritis.
Rodriguez-Castro KI, Franceschi M, Noto A, Miraglia C, Nouvenne A, Leandro G, Meschi T, De' Angelis GL, Di Mario F
Acta Biomed 2018 Dec 17;89(8-S):88-92. doi: 10.23750/abm.v89i8-S.7921. PMID: 30561424Free PMC Article
Gastritis and carditis.
Owen DA
Mod Pathol 2003 Apr;16(4):325-41. doi: 10.1097/01.MP.0000062995.72390.14. PMID: 12692198
Dyspepsia update.
Colin-Jones DG
Scand J Gastroenterol Suppl 1995;210:32-5. doi: 10.3109/00365529509090266. PMID: 8578202

Diagnosis

Clinical manifestations of chronic atrophic gastritis.
Rodriguez-Castro KI, Franceschi M, Noto A, Miraglia C, Nouvenne A, Leandro G, Meschi T, De' Angelis GL, Di Mario F
Acta Biomed 2018 Dec 17;89(8-S):88-92. doi: 10.23750/abm.v89i8-S.7921. PMID: 30561424Free PMC Article
Gastritis and carditis.
Owen DA
Mod Pathol 2003 Apr;16(4):325-41. doi: 10.1097/01.MP.0000062995.72390.14. PMID: 12692198
Foregut duplications.
Carachi R, Azmy A
Pediatr Surg Int 2002 Sep;18(5-6):371-4. Epub 2002 May 9 doi: 10.1007/s00383-002-0835-y. PMID: 12415358
Dieulafoy's disease.
Fockens P, Tytgat GN
Gastrointest Endosc Clin N Am 1996 Oct;6(4):739-52. PMID: 8899405
Acute stress ulceration.
Hillman K
Anaesth Intensive Care 1985 Aug;13(3):230-40. doi: 10.1177/0310057X8501300302. PMID: 2864881

Therapy

AGA Clinical Practice Update on Endoscopic Treatment of Barrett's Esophagus With Dysplasia and/or Early Cancer: Expert Review.
Sharma P, Shaheen NJ, Katzka D, Bergman JJGHM
Gastroenterology 2020 Feb;158(3):760-769. Epub 2019 Nov 12 doi: 10.1053/j.gastro.2019.09.051. PMID: 31730766
Increased susceptibility of aging gastric mucosa to injury: the mechanisms and clinical implications.
Tarnawski AS, Ahluwalia A, Jones MK
World J Gastroenterol 2014 Apr 28;20(16):4467-82. doi: 10.3748/wjg.v20.i16.4467. PMID: 24782600Free PMC Article
Dyspepsia update.
Colin-Jones DG
Scand J Gastroenterol Suppl 1995;210:32-5. doi: 10.3109/00365529509090266. PMID: 8578202
Epidemic hypochlorhydria.
Gledhill T, Leicester RJ, Addis B, Lightfoot N, Barnard J, Viney N, Darkin D, Hunt RH
Br Med J (Clin Res Ed) 1985 May 11;290(6479):1383-6. doi: 10.1136/bmj.290.6479.1383. PMID: 3922503Free PMC Article
Acute stress ulceration.
Hillman K
Anaesth Intensive Care 1985 Aug;13(3):230-40. doi: 10.1177/0310057X8501300302. PMID: 2864881

Prognosis

Helicobacter pylori-induced RASAL2 Through Activation of Nuclear Factor-κB Promotes Gastric Tumorigenesis via β-catenin Signaling Axis.
Cao L, Zhu S, Lu H, Soutto M, Bhat N, Chen Z, Peng D, Lin J, Lu J, Li P, Zheng C, Huang C, El-Rifai W
Gastroenterology 2022 May;162(6):1716-1731.e17. Epub 2022 Feb 5 doi: 10.1053/j.gastro.2022.01.046. PMID: 35134322Free PMC Article
Nutrition status and Helicobacter pylori infection in patients receiving hemodialysis.
Sugimoto M, Yasuda H, Andoh A
World J Gastroenterol 2018 Apr 21;24(15):1591-1600. doi: 10.3748/wjg.v24.i15.1591. PMID: 29686466Free PMC Article
Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications.
Yamashita K, Sakuramoto S, Watanabe M
Surg Today 2011 Jan;41(1):24-38. Epub 2010 Dec 30 doi: 10.1007/s00595-010-4370-5. PMID: 21191688
Dieulafoy's disease.
Fockens P, Tytgat GN
Gastrointest Endosc Clin N Am 1996 Oct;6(4):739-52. PMID: 8899405
Collagenous gastritis.
Colletti RB, Trainer TD
Gastroenterology 1989 Dec;97(6):1552-5. doi: 10.1016/0016-5085(89)90403-4. PMID: 2583419

Clinical prediction guides

Analysis of risks of gastric cancer by gastric mucosa among Indonesian ethnic groups.
Miftahussurur M, Waskito LA, Syam AF, Nusi IA, Wibawa IDN, Rezkitha YAA, Siregar G, Yulizal OK, Akil F, Uwan WB, Simanjuntak D, Waleleng JB, Saudale AMJ, Yusuf F, Maulahela H, Richardo M, Rahman A, Namara YS, Sudarmo E, Adi P, Maimunah U, Setiawan PB, Fauzia KA, Doohan D, Uchida T, Lusida MI, Yamaoka Y
PLoS One 2019;14(5):e0216670. Epub 2019 May 9 doi: 10.1371/journal.pone.0216670. PMID: 31071187Free PMC Article
Helicobacter pylori infection in gastric mucosa-associated lymphoid tissue lymphoma.
Park JB, Koo JS
World J Gastroenterol 2014 Mar 21;20(11):2751-9. doi: 10.3748/wjg.v20.i11.2751. PMID: 24659867Free PMC Article
Src family kinases and paclitaxel sensitivity.
Le XF, Bast RC Jr
Cancer Biol Ther 2011 Aug 15;12(4):260-9. doi: 10.4161/cbt.12.4.16430. PMID: 21646863Free PMC Article
Stem cells and gastric cancer: role of gastric and intestinal mixed intestinal metaplasia.
Tatematsu M, Tsukamoto T, Inada K
Cancer Sci 2003 Feb;94(2):135-41. doi: 10.1111/j.1349-7006.2003.tb01409.x. PMID: 12708487
Portal hypertensive gastropathy.
Triger DR
Baillieres Clin Gastroenterol 1992 Sep;6(3):481-95. doi: 10.1016/0950-3528(92)90034-c. PMID: 1421596

Recent systematic reviews

Parietal cell/oncocytic gastric carcinoma: systematic review and first-time assessment of HER2 status in two new cases.
Mavroeidis VK, Gkegkes ID, Saffioti F, Kandilaris K, Alexiou K, Horti M, Economou N, Demonakou M
Ann R Coll Surg Engl 2020 Apr;102(4):300-307. Epub 2020 Jan 13 doi: 10.1308/rcsann.2019.0183. PMID: 31928359Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • GTR
      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...