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Serous adenofibroma

MedGen UID:
87253
•Concept ID:
C0334498
•
Neoplastic Process
Synonyms: Serous Adenofibroma; serous adenofibroma; Serous cystadenofibroma
SNOMED CT: Serous adenofibroma (2026006); Serous cystadenofibroma (2026006)
 
Monarch Initiative: MONDO:0024886

Definition

A benign or borderline adenofibroma characterized by the presence of serous secretory cells and minute cystic spaces filled with watery fluid. A representative example is the ovarian serous adenofibroma. [from NCI]

Professional guidelines

PubMed

Clear cell carcinoma of the ovary: is there a role of histology-specific treatment?
Takano M, Tsuda H, Sugiyama T
J Exp Clin Cancer Res 2012 Jun 1;31(1):53. doi: 10.1186/1756-9966-31-53. PMID: 22655678Free PMC Article

Recent clinical studies

Diagnosis

Giant serous adenofibroma of the fallopian tube.
Tavares MA, Silva RC, Lourenço M, Ambrósio A
BMJ Case Rep 2020 Jun 9;13(6) doi: 10.1136/bcr-2020-234267. PMID: 32522722Free PMC Article
Glucocorticoid resistance syndrome caused by a novel NR3C1 point mutation.
Al Argan R, Saskin A, Yang JW, D'Agostino MD, Rivera J
Endocr J 2018 Nov 29;65(11):1139-1146. Epub 2018 Aug 30 doi: 10.1507/endocrj.EJ18-0135. PMID: 30158362
Poor man's NOTES: can it be a good approach for adhesiolysis? A first case report with video demonstration.
Baekelandt J
J Minim Invasive Gynecol 2015 Mar-Apr;22(3):319. Epub 2014 Nov 10 doi: 10.1016/j.jmig.2014.11.001. PMID: 25460516
Adenofibroma of the testis.
Gatt N, Attard J, Degaetano J
J Clin Pathol 2009 Jun;62(6):558-60. doi: 10.1136/jcp.2008.064006. PMID: 19474357
Pathologic quiz case: a 54-year-old woman with bilateral pelvic masses. Well-differentiated papillary serous carcinoma arising in serous adenofibroma of borderline malignancy.
Carter A, Quddus MR, Sung CJ, Lawrence WD
Arch Pathol Lab Med 2005 Jan;129(1):e25-6. doi: 10.5858/2005-129-e25-PQCAYW. PMID: 15628924

Prognosis

Ciliated adenocarcinoma of the ovary with evidence of serous differentiation: report of a case.
Sciallis AP, Aubry MC, Bell DA
Int J Gynecol Pathol 2009 Sep;28(5):447-52. doi: 10.1097/PGP.0b013e3181a0717f. PMID: 19696614

Clinical prediction guides

Ciliated adenocarcinoma of the ovary with evidence of serous differentiation: report of a case.
Sciallis AP, Aubry MC, Bell DA
Int J Gynecol Pathol 2009 Sep;28(5):447-52. doi: 10.1097/PGP.0b013e3181a0717f. PMID: 19696614

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