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Mixed Mesodermal (Mullerian) Tumor

MedGen UID:
64619
•Concept ID:
C0206627
•
Neoplastic Process
Synonyms: Mixed Tumor, Mullerian; Mullerian Mixed Tumor; Tumor, Mullerian Mixed

Definition

A group of tumors affecting the female reproductive system, characterized by the presence of epithelial and stromal elements. It includes the following clinicopathological entities: adenofibroma, adenomyoma, Mullerian adenosarcoma, and malignant mixed mesodermal (Mullerian) tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMixed Mesodermal (Mullerian) Tumor

Professional guidelines

PubMed

Tamoxifen treatment for breast cancer and risk of endometrial cancer: a case-control study.
Swerdlow AJ, Jones ME; British Tamoxifen Second Cancer Study Group
J Natl Cancer Inst 2005 Mar 2;97(5):375-84. doi: 10.1093/jnci/dji057. PMID: 15741574
Uterine sarcomas: prognostic factors and treatment modalities--study on 209 patients.
George M, Pejovic MH, Kramar A
Gynecol Oncol 1986 May;24(1):58-67. doi: 10.1016/0090-8258(86)90008-9. PMID: 3699577

Recent clinical studies

Etiology

Sarcomatoid carcinoma with osseous differentiation in the bladder.
Arenas LF, Fontes DA, Pereira EM, Hering FL
Int Braz J Urol 2006 Sep-Oct;32(5):563-5. doi: 10.1590/s1677-55382006000500010. PMID: 17081326
Platinum-based combination chemotherapy for malignant mixed mesodermal tumors of the ovary.
Andersen WA, Young DE, Peters WA 3rd, Smith EB, Bagley CM, Taylor PT Jr
Gynecol Oncol 1989 Mar;32(3):319-22. doi: 10.1016/0090-8258(89)90632-x. PMID: 2537779

Diagnosis

Platinum-based combination chemotherapy for malignant mixed mesodermal tumors of the ovary.
Andersen WA, Young DE, Peters WA 3rd, Smith EB, Bagley CM, Taylor PT Jr
Gynecol Oncol 1989 Mar;32(3):319-22. doi: 10.1016/0090-8258(89)90632-x. PMID: 2537779

Therapy

Sarcomatoid carcinoma with osseous differentiation in the bladder.
Arenas LF, Fontes DA, Pereira EM, Hering FL
Int Braz J Urol 2006 Sep-Oct;32(5):563-5. doi: 10.1590/s1677-55382006000500010. PMID: 17081326
Platinum-based combination chemotherapy for malignant mixed mesodermal tumors of the ovary.
Andersen WA, Young DE, Peters WA 3rd, Smith EB, Bagley CM, Taylor PT Jr
Gynecol Oncol 1989 Mar;32(3):319-22. doi: 10.1016/0090-8258(89)90632-x. PMID: 2537779

Prognosis

Primary peritoneal malignant mixed mesodermal (Müllerian) tumor.
Hussein MR, Hussein SR, Abd-Elwahed AR
Tumori 2009 Jul-Aug;95(4):525-31. doi: 10.1177/030089160909500421. PMID: 19856669
Sarcomatoid carcinoma with osseous differentiation in the bladder.
Arenas LF, Fontes DA, Pereira EM, Hering FL
Int Braz J Urol 2006 Sep-Oct;32(5):563-5. doi: 10.1590/s1677-55382006000500010. PMID: 17081326
Primary mesenteric malignant mixed mesodermal (müllerian) tumor with neuroendocrine differentiation.
Cokelaere K, Michielsen P, De Vos R, Sciot R
Mod Pathol 2001 May;14(5):515-20. doi: 10.1038/modpathol.3880340. PMID: 11353063

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