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Items: 1 to 20 of 150

1.

Gene expression level of HEI-286 Schwann cells and MiaPaCa-2 pancreatic cancer cells

(Submitter supplied) We report the transcriptome analysis of HEI-286 human Schwann cells and MiaPaCa-2 pancreatic cancer cells Nerves stimulate cancer progression for different cancer types, promoting both tumor growth and perineural invasion, a prominent process in pancreatic ductal adenocarcinoma. Yet little is known about how cells in the nerves contribute to cancer progression. Here we demonstrate that Schwann cells, the most abundant cell type in nerves, collectively function as tumor activated Schwann cell tracks (TASTs). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
8 Samples
Download data: TXT
Series
Accession:
GSE180971
ID:
200180971

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Sleep Disturbance and Activation of Cellular and Transcriptional Mechanisms of Inflammation in Older Adults

(Submitter supplied) Genome-wide transcriptional profiling results were used to systematically assess the extent to which transcriptomes of older adults with insomnia show expression of genes that are different from those without insomnia
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
42 Samples
Download data
Series
Accession:
GSE208668
ID:
200208668

PubMed Similar studies Analyze with GEO2R

3.

Expression profile and Histone H3 K4, K9, K27, K36 tri-methylation occupancy through the whole genome between control and AMPK knockdown Hep3B cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL10904 GPL11154
21 Samples
Download data: BIGWIG, IDAT
Series
Accession:
GSE97191
ID:
200097191

Analyze with GEO2R

4.

Gene expression profiling of control and AMPK knockdown Hep3B cells

(Submitter supplied) Gene expression profiling of control and AMPK knockdown Hep3B cells
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
9 Samples
Download data: IDAT, TXT
Series
Accession:
GSE97155
ID:
200097155

Analyze with GEO2R

5.

Microarray analysis of HeLa Parental vs HeLa radio-resistant tumour xenograft in mice

(Submitter supplied) Analysis of differential gene expression in HeLa Parental vs radio-resistant xenograft tumours. The aim is to identify potential genes that are deregulated in radio-resistant tumours.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
4 Samples
Download data: IDAT
Series
Accession:
GSE181080
ID:
200181080

PubMed Similar studies Analyze with GEO2R

6.

RA-MAP: mapping the molecular immunological landscape in early rheumatoid arthritis with vaccine controls [6 month RA, Whole Blood, PBMC, CD4, CD8, CD14]

(Submitter supplied) Rheumatoid arthritis (RA) is a chronic inflammatory disorder with poorly defined aetiology characterised by synovial inflammation with variable disease severity and drug responsiveness. To investigate the peripheral blood immune cell landscape of RA, we performed comprehensive clinical and molecular profiling of 267 RA patients and 52 vaccine recipient controls for up to 18 months to establish a high quality sample biobank including plasma, serum, peripheral blood cells, urine, genomic DNA, RNA from whole blood, lymphocyte and monocyte subsets. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
1126 Samples
Download data: TXT
Series
Accession:
GSE97948
ID:
200097948

PubMed Full text in PMC Similar studies Analyze with GEO2R

7.

RA-MAP: mapping molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients [Baseline RA, Whole Blood, PBMC, CD4, CD8, CD14]

(Submitter supplied) Rheumatoid arthritis (RA) is a chronic inflammatory disorder with poorly defined aetiology characterised by synovial inflammation with variable disease severity and drug responsiveness. To investigate the peripheral blood immune cell landscape of RA, we performed comprehensive clinical and molecular profiling of 267 RA patients and 52 vaccine recipient controls for up to 18 months to establish a high quality sample biobank including plasma, serum, peripheral blood cells, urine, genomic DNA, RNA from whole blood, lymphocyte and monocyte subsets. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
1068 Samples
Download data: TXT
Series
Accession:
GSE97810
ID:
200097810

PubMed Full text in PMC Similar studies Analyze with GEO2R

8.

RA-MAP: mapping molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL11154 GPL10904
5066 Samples
Download data: TXT
Series
Accession:
GSE97476
ID:
200097476

PubMed Full text in PMC Similar studies Analyze with GEO2R

9.

RA-MAP: mapping molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients [Healthy Hepatitis B Vaccine Recipients]

(Submitter supplied) Rheumatoid arthritis (RA) is a chronic inflammatory disorder with poorly defined aetiology characterised by synovial inflammation with variable disease severity and drug responsiveness. To investigate the peripheral blood immune cell landscape of RA, we performed comprehensive clinical and molecular profiling of 267 RA patients and 52 vaccine recipient controls for up to 18 months to establish a high quality sample biobank including plasma, serum, peripheral blood cells, urine, genomic DNA, RNA from whole blood, lymphocyte and monocyte subsets. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
158 Samples
Download data: TXT
Series
Accession:
GSE97475
ID:
200097475

PubMed Full text in PMC Similar studies Analyze with GEO2R

10.

Transcriptional profiling of primary human keratinocytes treated with interferon gamma and/or infected with HSV-2 using Illumina beadarray

(Submitter supplied) We aim to analyze the transcriptional profiles of primary human keratinocytes in response to interferon gamma (IFNG) treatment and/or HSV-2 (strain HG-52) infection. The goal is to define IFNG regulated intrinsic immunity of primary human keratinocytes and how HSV-2 infection regulates the intrinsic immunity of primary human keratinocyte.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
8 Samples
Download data: TXT
Series
Accession:
GSE172424
ID:
200172424

PubMed Full text in PMC Similar studies Analyze with GEO2R

11.

Transcriptional profiling of human genital skin biopsies at lesion, 2- and 8-weeks post healing and contra-lateral control genital skin biopsies during recurrent HSV-2 infection

(Submitter supplied) Analysis of host response at the gene expression level during lesion and post healing periods (2- & 8-weeks after HSV-2 reactivation induced lesion is resolved). We would like to get a comprehensive overview on host gene expression of genital skin during lesion and post healing periods of recurrent HSV-2 infection as compared to those in control skin.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
104 Samples
Download data: TXT
Series
Accession:
GSE172423
ID:
200172423

PubMed Full text in PMC Similar studies Analyze with GEO2R

12.

Aflatoxin B1 attenuates endocrine function, protein synthesis and energy production of human primary trophoblast

(Submitter supplied) Aflatoxin B1 (AFB1) is a mycotoxin produced by Aspergillus flavus and A. parasiticus. AFB1 targeted gene expression profiles were determined in human primary trophoblast cells, isolated from full term placentae after delivery, and exposed to 1 µM AFB1 for 72 hours. Gene expression profiling conducted with human HT-12 expression beadchips
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
8 Samples
Download data: TXT
Series
Accession:
GSE153590
ID:
200153590

PubMed Full text in PMC Similar studies Analyze with GEO2R

13.

Transcriptome Analysis of Bladder Cancer Cell Persistently Infected by Newcastle disease virus (NDV)

(Submitter supplied) This project seeks to determine if there is a difference in expression between bladder cancer cells vs NDV-resistant bladder cancer cells.This result provides insight of the orchestrated transcriptomic changes that occur in the development and maintenance of NDV persistency of infection, which can be an useful resource for future downstream analysis of the identified targets.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
6 Samples
Download data: TXT
Series
Accession:
GSE163881
ID:
200163881

PubMed Full text in PMC Similar studies

14.

Molecular mechanism of EPC1-PHF1 fusion protein

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL10904 GPL11154
20 Samples
Download data: BW
Series
Accession:
GSE162544
ID:
200162544

Analyze with GEO2R

15.

Molecular mechanism of EPC1-PHF1 fusion protein (Microarray Homo Sapiens)

(Submitter supplied) In this study, we characterize the fusion protein produced by the EPC1-PHF1 translocation in Low Grade Endometrial Stromal Sarcoma (LG-ESS) and Ossifying FibroMyxoid Tumors (OFMT). We express the fusion protein and necessary controls in K562 Cells. The fusion protein assembles a mega-complex harboring both NuA4/TIP60 and PRC2 subunits and enzymatic activities and leads to mislocalization of chromatin marks in the genome, linked to aberrant gene expression.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
8 Samples
Download data: TXT
Series
Accession:
GSE162543
ID:
200162543

Analyze with GEO2R

16.

Integrative genomic meta-analysis reveals novel molecular insights into cystic fibrosis and ΔF508-CFTR rescue

(Submitter supplied) Cystic fibrosis (CF), caused by mutations to CFTR, leads to severe and progressive lung disease. The most common mutant, ΔF508-CFTR, undergoes proteasomal degradation, depleting its anion channel function. “Proteostasis” pathways, i.e. those relevant to protein processing and trafficking, are altered in cells with ΔF508-CFTR and can be modulated to partially rescue protein function. However, many details regarding proteostasis modulation, and its relevance to CF and ΔF508-CFTR rescue, remain poorly understood. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
60 Samples
Download data: TXT
Series
Accession:
GSE142610
ID:
200142610

PubMed Full text in PMC Similar studies Analyze with GEO2R

17.

Transcriptional correlates of high norepinephrine content in ovarian carcinomas

(Submitter supplied) Genome-wide transcriptome profiling was conducted on 97 Stage I-IV ovarian carcinomas classified according to tissue norepinephrine content.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
97 Samples
Download data: TXT
Series
Accession:
GSE103737
ID:
200103737

Analyze with GEO2R

18.

Interleukin-33 in experimental kidney fibrosis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array
Platforms:
GPL10904 GPL15097
28 Samples
Download data: IDAT
Series
Accession:
GSE149918
ID:
200149918

PubMed Full text in PMC Similar studies Analyze with GEO2R

19.

Knockdown of interleukin-33 in human fibroblasts

(Submitter supplied) Interleukin (IL)-33 is a cytokine that appears to mediate fibrosis by signaling via its receptor ST2 (IL-33R/IL1RL1). It is also, however, a protein that after synthesis is sorted to the cell nucleus, where it appears to affect chromatin folding. Here we describe a novel role for nuclear IL-33 in regulating the fibroblast phenotype in murine kidney fibrosis driven by unilateral ureteral obstruction. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
12 Samples
Download data: IDAT
Series
Accession:
GSE149917
ID:
200149917

PubMed Full text in PMC Similar studies Analyze with GEO2R

20.

Gene expression data from study on the role of DISC1 607 variants on immune responses against Toxoplasma gondii

(Submitter supplied) A major mental illness-related susceptibility factor, Disrupted in schizophrenia (DISC1), is involved in altered host immune responses against Toxoplasma gondii (T. gondii) infection. Specifically, our gene expression studies have revealed that DISC1 Leu607Phe variation, which changes DISC1 interaction with activating transcription factor 4 (ATF4), modifies gene expression patterns upon T. gondii infection.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10904
12 Samples
Download data: IDAT
Series
Accession:
GSE113806
ID:
200113806

Analyze with GEO2R

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