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Items: 1 to 20 of 26

1.

Diphthamide modification of eEF2 is required for gut tumor-like hyperplasia induced by oncogenic Ras

(Submitter supplied) Eukaryotic elongation factor 2 (eEF2) undergoes a unique post-translational modification called diphthamidation. Although eEF2 diphthamidation is highly conserved, its pathophysiological function is still largely unknown. To elucidate the function of diphthamidation in tumor, we examined the involvement of diphthamidation pathway enzyme Dph5 in tumor progression in Drosophila adult gut. Expression of oncogenic RasV12 in gut intestinal stem cells (ISCs) and enteroblasts (EBs) causes hypertrophy and disruption of gut epithelia, and shortened lifespan. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL17277
14 Samples
Download data: TXT
Series
Accession:
GSE141201
ID:
200141201

PubMed Similar studies Analyze with GEO2R

2.

The gene expression changes in darkcd4 apoptosis-deficient mutant flies

(Submitter supplied) Apoptosis is required not only for proper morphogenesis and tissue size regulation during development, but also for removing damaged or unwanted cells to maintain homeostasis. Apoptosis is mainly executed by evolutionally-conserved signaling process including caspases and its activator, dark. We performed microarray analysis of darkcd4 mutant flies to reveal the changes in gene expression. We found the elevated immune reaction, suggesting that inflammatory response was triggered by necrosis in darkcd4 .
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL17277
8 Samples
Download data: TXT
Series
Accession:
GSE47853
ID:
200047853

PubMed Similar studies Analyze with GEO2R

3.

Agilent-040871 Drosophila melanogaster 8X60K with Spike (Probe Name version)

(Submitter supplied) Arrays of this design have barcodes that begin with 16040871 or 2540871. Protocol: See manufacturer's web site at http://www.agilent.com/.
Organism:
Drosophila melanogaster
2 Series
1 Related Platform
22 Samples
Download data
Platform
Accession:
GPL17277
ID:
100017277

PubMed Similar studies

4.

Agilent-040871 Drosophila melanogaster 8X60K with Spike (Feature Number version)

(Submitter supplied) Arrays of this design have barcodes that begin with 16040871 or 2540871. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. Rows and columns are numbered as scanned by an Axon Scanner (barcode on the bottom, DNA on the front surface). more...
Organism:
Drosophila melanogaster
1 Series
1 Related Platform
15 Samples
Download data
Platform
Accession:
GPL17276
ID:
100017276

PubMed Similar studies

5.

Ras[V12]+Dph5IR_4

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197136
ID:
304197136

6.

Ras[V12]+Dph5IR_3

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197135
ID:
304197135

7.

Ras[V12]+Dph5IR_2

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197134
ID:
304197134

8.

Ras[V12]+Dph5IR_1

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197133
ID:
304197133

9.

Ras[V12]+LacZIR_4

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197132
ID:
304197132

10.

Ras[V12]+LacZIR_3

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197131
ID:
304197131

11.

Ras[V12]+LacZIR_2

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197130
ID:
304197130

12.

Ras[V12]+LacZIR_1

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197129
ID:
304197129

13.

Dph5IR_4

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197128
ID:
304197128

14.

Dph5IR_3

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197127
ID:
304197127

15.

Dph5IR_2

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197126
ID:
304197126

16.

Dph5IR_1

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197125
ID:
304197125

17.

LacZIR_2

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197124
ID:
304197124

18.

LacZIR_1

Organism:
Drosophila melanogaster
Source name:
adult male whole gut expressing transgenes under the control of esg[ts]-Gal4, 2days at 29 degree
Platform:
GPL17277
Series:
GSE141201
Download data: TXT
Sample
Accession:
GSM4197123
ID:
304197123

19.

darkcd4_rep4

Organism:
Drosophila melanogaster
Source name:
whole body, darkcd4 mutant
Platform:
GPL17277
Series:
GSE47853
Download data: TXT
Sample
Accession:
GSM1160685
ID:
301160685

20.

darkcd4_rep3

Organism:
Drosophila melanogaster
Source name:
whole body, darkcd4 mutant
Platform:
GPL17277
Series:
GSE47853
Download data: TXT
Sample
Accession:
GSM1160684
ID:
301160684

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