GPL6955[RGSE] - GEO DataSets

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Select item 2000529161.

The role of viral microRNAs in Burkitt Lymphoma: the Epstein Barr-encoded Bart-6-3p microRNA regulates cell proliferation and immunosurveillance

(Submitter supplied) Compare Epstein-Barr-positive and Epstein-Barr-negative Burkitt lymphoma cases forboth cellular and viral microRNA expression profile, and to assess the role of viralmicroRNAs in Burkitt lymphomagenesis

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
18 Samples

Download data: TXT

Series

Accession:: GSE52916

ID:: 200052916

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000479772.

Ozone Exposure Alters MicroRNA Expression Profiles in Humans

(Submitter supplied) We set out to test the hypothesis that ozone inhalation exposure significantly alters miRNA expression profiles within the airway of humans. Adult human volunteers were exposed to 0.4 ppm ozone for two hours. Induced sputum samples were collected from each subject 48 hours pre-exposure and 6 hours post-exposure. Genome-wide miRNA expression profiles were evaluated using microarray analysis.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
40 Samples

Download data: TXT

Series

Accession:: GSE47977

ID:: 200047977

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000413603.

Multiple platform assessment and isomir analysis of the EGF dependent microRNA-ome by microarray and deep sequencing analysis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: human gammaherpesvirus 4; Human gammaherpesvirus 8; Betapolyomavirus macacae; Human alphaherpesvirus 1; Homo sapiens; Human betaherpesvirus 5; Betapolyomavirus hominis; JC polyomavirus; Human immunodeficiency virus 1

Type:: Non-coding RNA profiling by array; Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL9115 GPL6955 GPL16118
20 Samples

Download data: TXT

Series

Accession:: GSE41360

ID:: 200041360

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000411814.

Multiple platform assessment and isomir analysis of the EGF dependent microRNA-ome by microarray and deep sequencing analysis [Agilent]

(Submitter supplied) We have used an integrative high content analysis approach to identify the specific miRNAs implicated in EGF signaling in HeLa cells as potential mediators of cancer mediated functions. We have used microarray and deep-sequencing technologies in order to obtain a global view of the EGF miRNA transcriptome with a robust experimental cross-validation. By applying a procedure based on Rankprod tests, we have delimited a solid set of EGF-regulated miRNAs. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
8 Samples

Download data: TXT

Series

Accession:: GSE41181

ID:: 200041181

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000349785.

Formaldehyde and Epigenetic Alterations: MicroRNA Changes in the Nasal Epithelium of Nonhuman Primates

(Submitter supplied) We set out to test the hypothesis that formaldehyde inhalation exposure significantly alters miRNA expression profiles within the nasal epithelium of nonhuman primates. Here, cynomolgus macaques were exposed to 0, 2, and 6 ppm formaldehyde for 6 hours/day across two consecutive days. RNA was extracted from the nasal maxilloturbinate region, a direct target of formaldehyde inhalation exposure. Genome-wide miRNA expression levels were assessed using microarrays.

Organism:: Macaca fascicularis; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
8 Samples

Download data: TXT

Series

Accession:: GSE34978

ID:: 200034978

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000306566.

Altered microRNA expression associated with chromosomal and epigenetic changes contributes to cervical carcinogenesis

(Submitter supplied) Little is known about the alterations in microRNA (miRNA) expression patterns during the consecutive stages of cervical cancer development and their association with chromosomal instability and epigenetic changes. We integrated miRNA expression profiles in normal cervical squamous epithelium, high-grade precancerous lesions (CIN2-3), squamous cell carcinomas (SCC) and adenocarcinomas (AdCAs) with previously generated chromosomal profiles of the same samples. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
47 Samples

Download data: TXT

Series

Accession:: GSE30656

ID:: 200030656

Select item 2000333387.

miRNA changes in mild and moderate emphysema correlate with target gene expression in vivo and in vitro

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array; Expression profiling by array

Platforms:: GPL6955 GPL6947
39 Samples

Download data: TXT

Series

Accession:: GSE33338

ID:: 200033338

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000333368.

Development of microRNA expression signature for emphysema in COPD patients

(Submitter supplied) To define the role of microRNAs and their mRNA targets in emphysema severity in COPD patients.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
31 Samples

Download data: TXT

Series

Accession:: GSE33336

ID:: 200033336

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000289559.

A set of 72 differentially expressed miRNAs provide a molecular signature for pancreatic cancer

(Submitter supplied) MicroRNAs (miRNAs) are short single-stranded RNA molecules that have a critical role in the regulation of gene expression. Alterations in miRNA expression levels have been observed in multiple tumor types and there is clear evidence on their active involvement in cancer development. Here, a comprehensive miRNA expression profiling in 16 pancreatic cancer cell lines and four normal pancreatic samples provided a specific molecular signature for pancreatic cancer and enabled us to identify 72 differentially expressed miRNAs with approximately half of them being up- and half downregulated in cancer cells as compared to normal samples. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
23 Samples

Download data: TXT

Series

Accession:: GSE28955

ID:: 200028955

Analyze with GEO2R

Select item 20002565310.

miRNA profiling of Melanoma Cell lines and Normal Melanocytes

(Submitter supplied) To identify microRNAs potentially involved in melanomagenesis we compared microRNA transcription profiles between melanoma cell lines and cultured melanocytes.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
56 Samples

Download data: TXT

Series

Accession:: GSE25653

ID:: 200025653

Select item 20002490811.

Human Papillomavirus 16 E5 modulates the expression of host microRNAs

(Submitter supplied) The effect of human papillomavirus 16 E5 oncogene on cellular gene expression in human epithelial cells was studied.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL6955 GPL4133
40 Samples

Download data: GPR

Series

Accession:: GSE24908

ID:: 200024908

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002990012.

microRNA expression signatures in colorectal cancer cell lines with demethylating treatment

(Submitter supplied) To screen for epigenetically silenced miRNAs, wecarried out miRNA microarray analysis in three colorectal cancer (CRC) cell lines (HCT116, DLD-1 and RKO) treated with or without 5-aza-2'-deoxycytidine (aza). HCT116 and RKO cells were also treated with aza plus 4-phenylbutyric acid (PBA). In addition, we analyzed HCT116 cells in which the DNA methyltransferase genes DNMT1 and DNMT3B were genetically disrupted (double knockout; DKO cells), thereby abrogating DNA methylation. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
10 Samples

Download data: TXT

Series

Accession:: GSE29900

ID:: 200029900

Select item 20002783413.

miR-371-3 expression predicts neural differentiation potential in human pluripotent stem cells

(Submitter supplied) The use of pluripotent stem cells in regenerative medicine and disease modeling is complicated by the variation in differentiation properties between lines. In this study, we characterized 13 human embryonic stem cell. (hESC) and 26 human induced pluripotent stem cell (hiPSC) lines to identify markers that predict neural differentiation behavior. At a general level, markers previously known to distinguish mouse ESCs from epiblast stem cells (EpiSCs) correlated with neural differentiation behavior. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL6955 GPL6104
32 Samples

Download data: TXT

Series

Accession:: GSE27834

ID:: 200027834

Select item 20002499614.

miR-193b Regulates Mcl-1 in Melanoma

(Submitter supplied) MicroRNAs (miRNAs) have important roles in gene regulation. Dysregulation of miRNAs has been associated with tumorigenesis. Recent studies suggest miR-193b is a tumor suppressor gene. In a previous study, we reported that miR-193b represses cell proliferation and regulates cyclin D1 (CCND1) in melanoma. Now we demonstrate that miR-193b regulates myeloid cell leukemia sequence 1 (Mcl-1) in melanoma cells. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
31 Samples

Download data: TXT

Series

Accession:: GSE24996

ID:: 200024996

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002236515.

miRNA expression data from A549 exposed to formaldehyde

(Submitter supplied) We are investigating the miRNA expression profiles of human lung cells to gaseous formaldehyde We used microarrays to detail the global programme of miRNA expression upon response to formaldehyde

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
6 Samples

Download data: TXT

Series

Accession:: GSE22365

ID:: 200022365

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001331616.

miRNA expression data in idiopathic pulmonary fibrosis

(Submitter supplied) Idiopathic pulmonary fibrosis (IPF) is an untreatable fibrotic lung disease characterized by fibroblast proliferation and epithelial mesenchymal transition. The expression and role of microRNAs (miRNA) has not been studied in IPF. Using miRNA expression microarrays we identified 46 differentially expressed miRNA in IPF lungs which included let-7d and the miR-30 family. Keywords: miRNA expression

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
20 Samples

Download data: TXT

Series

Accession:: GSE13316

ID:: 200013316

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001538717.

microRNA and mRNA expression in human hepatitis C Virus

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL887 GPL6955
153 Samples

Download data: TXT

Series

Accession:: GSE15387

ID:: 200015387

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001528818.

microRNA expression in human hepatitis c virus (HCV) liver biopsy samples

(Submitter supplied) In order to infer the inverse expression relationships between microRNAs and mRNAs during HCV infection, we profiled both microRNA and mRNA expressions in HCV positive (HCV+) and HCV negative (HCV-) human liver biopsy tissue samples. This series includes all microRNA profiles.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
36 Samples

Download data: TXT

Series

Accession:: GSE15288

ID:: 200015288

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001645619.

MicroRNA expression signatures in Barrett's esophagus and esophageal adenocarcinoma

(Submitter supplied) Esophageal adenocarcinoma (EAC) is a highly aggressive malignancy that frequently develops from Barrett’s esophagus (BE), a premalignant pathological change occurring in the lower end of esophagus. To identify BE patients at high risk of malignant transformation is essential to the prevention of EAC. Although microRNA (miRNA) expression signatures have been associated with the etiology and prognosis of several types of cancers, their roles in the development of EAC have not been extensively evaluated.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL6955
32 Samples

Download data: TXT

Series

Accession:: GSE16456

ID:: 200016456

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001485720.

MicroRNA Profiling Identifies Potential Diagnostic and Prognostic Markers in Prostate Cancer

(Submitter supplied) Prostate cancer is the second leading cause of cancer death in the United States and Europe. Diagnosis and risk estimation of cancer recurrence is often critical with the common clinicopathologic parameters of prostate-specific antigen, tumor stage and grade. Therefore it is mandatory to develop new diagnostic and prognostic markers for prostate cancer. miRNAs have been shown to be novel markers in a series of other cancer types. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6955
24 Samples

Download data: TIFF, XML

Series

Accession:: GSE14857

ID:: 200014857

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