GPL9448[RGSE] - GEO DataSets

Select item 2000552701.

ChIP-chip from HEK293-RPF-1 stable transfectants expressing the HA-tagged RPF-1 transcription factor

(Submitter supplied) RPF-1 binds promoters of genes modulated by its induction in HEK/RPF-1 transfectant Chromatin IP (ChIP) combined to chromatin array analysis (ChIP-chip) shows that RPF-1 transcription factor bind to promoter elements of genes repressed or activated by RPF-1 expression

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL9448
4 Samples

Download data: GFF, PAIR

Series

Accession:: GSE55270

ID:: 200055270

PubMed Similar studies

Select item 2000523012.

Chip-chip from Hepatocellular carcinoma (HCC) specimens with H3K27me3

(Submitter supplied) Epigenetic changes commonly occur in hepatocellular carcinoma (HCC) and are associated with aberrant gene expression. Recently, we demonstrated the pivotal role of abnormal H3K4me3 methylation, which is catalyzed by the menin/MLL, a TrxG family, in HCC development. Meanwhile, there is clear evidence that increasing global levels of H3K27me3 are activated in human primary HCC. To further elucidate the functional relatedness of the repressive H3K27me3 and active H3K4me3 histone remodeling in HCC, we performed H3K27me3 and H3K4me3 ChIP-on-chip screen using three HCC specimens and their adjacent tissues.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL9448
6 Samples

Download data: GFF, JPG, PAIR, XLSX

Series

Accession:: GSE52301

ID:: 200052301

Analyze with GEO2R

Select item 2000523003.

Chip-chip from HepG2 cells with EZH2, SUZ12 and H3K27me3

(Submitter supplied) Polycomb group (PcG) proteins including EZH2, SUZ12 and so on, which specifically catalyze trimethylation of histone 3 lysine 27 (H3K27me3), and methylated H3K27 can be recognized by other specific binding proteins to compress chromatin structure, leading to the transcriptional repression of the target genes. To completely understand the epigenetic profile and molecular network of PcG in HCC, we performed ChIP-on-chip screens with EZH2, SUZ12 and H3K27me3 antibodies in HepG2 cells.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL9448
3 Samples

Download data: GFF, JPG, PAIR, XLSX

Series

Accession:: GSE52300

ID:: 200052300

Select item 2000521904.

Chip-chip from Hepatocellular carcinoma (HCC) specimens with H3K4me3

(Submitter supplied) Epigenetic changes commonly occur in hepatocellular carcinoma (HCC) and are associated with aberrant gene expression. Recently, we demonstrated the pivotal role of abnormal H3K4me3 methylation, which is catalyzed by the menin/MLL, a TrxG family, in HCC development. Meanwhile, there is clear evidence that increasing global levels of H3K27me3 are activated in human primary HCC. To further elucidate the functional relatedness of the active H3K4me3 and repressive H3K27me3 histone remodeling in HCC, we performed H3K4me3 and H3K27me3 ChIP-on-chip screen using three HCC specimens and their adjacent tissues.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL9448
6 Samples

Download data: GFF, JPG, PAIR, XLSX

Series

Accession:: GSE52190

ID:: 200052190

Analyze with GEO2R

Select item 2000274615.

Genome-wide DNA methylation analyses in the brain reveal four differentially methylated regions between humans and non-human primates

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Macaca mulatta; Homo sapiens

Type:: Methylation profiling by genome tiling array

Platforms:: GPL13216 GPL9448
6 Samples

Download data: PAIR

Series

Accession:: GSE27461

ID:: 200027461

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000274596.

Human cerebral cortex DNA methylation by MeDIP-Chip

(Submitter supplied) The highly improved cognitive function is the most significant change in human evolutionary history. Recently, several large-scale studies reported the evolutionary roles of DNA methylation; however, the role of DNA methylation on brain evolution is largely unknown. To test if DNA methylation has contributed to the evolution of human brain, with the use of MeDIP-Chip and SEQUENOM MassARRAY, we conducted a genome-wide analysis to identify differentially methylated regions (DMRs) in the brain between humans and rhesus macaques. more...

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL9448
3 Samples

Download data: PAIR

Series

Accession:: GSE27459

ID:: 200027459

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000184577.

ChIP-chip from HCT116 cells treated with MMS and LNCaP cells with ATF3

(Submitter supplied) Maintenance of genetic integrity is essential for survival of all organisms. Activating transcription factor 3 (ATF3) is a member of the c-AMP response element binding (CREB)/ATF family of transcription factors, and is highly inducible by various stress conditions including DNA damage. However, downstream targets and molecular basis underlying pleiotropic effects of ATF3 on the cell fate have been largely unknown. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array; Expression profiling by array

Platforms:: GPL9448 GPL4133
10 Samples

Download data: BAR, BED, GFF, PAIR, PDF, TXT, XLS

Series

Accession:: GSE18457

ID:: 200018457

PubMed Full text in PMC Similar studies Analyze with GEO2R

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