GEO DataSets

Analysis of the hypothalamoneurohypophyseal system (HNS) in fluid-deprived males. The HNS components examined were hypothalamic paraventricular and supraoptic nuclei and neurointermediate lobe of the pituitary. Results identify candidate genes of HNS activity and remodeling induced by dehydration.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 protocol, 3 tissue sets

Platform:

GPL1355

Series:

GSE4130

30 Samples

Download data: CEL

Analysis of lens explant cultures grown overnight in the presence of 5 ng/mL FGF2 to promote proliferation and survival, then treated with 100 ng/mL FGF2 for up to 24hr to induce differentiation. Results provide insight into the molecular basis of FGF2-induced lens fiber cell differentiation.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 growth protocol, 5 time sets

Platform:

GPL1355

Series:

GSE50604

10 Samples

Download data: CEL

Analysis of epitrochlearis muscle from males exercised for 2hr then fed a whey protein hydrolysate (WPH) diet or a control diet with an identical amino acid composition (AAM). Results provide insight into the molecular basis of the greater post-exercise muscle protein synthesis in the WPH group.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 protocol sets

Platform:

GPL1355

Series:

GSE49486

8 Samples

Download data: CEL

Analysis of livers of males for up to 48 hours after treatment with a single, oral, nonseizure-inducing dose of 3 or 18 mg/kg hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). RDX is a synthetic, high-impact, stable explosive. Results provide insight into the acute effects of RDX on the liver.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 dose, 4 time sets

Platform:

GPL1355

Series:

GSE12196

24 Samples

Download data: CEL

Analysis of cerebral cortices of males for up to 48 hours after treatment with an oral, nonseizure-inducing dose of 3 or 18 mg/kg hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). RDX is a synthetic, high-impact, stable explosive. Results provide insight into the acute effects of RDX on the brain.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 dose, 4 time sets

Platform:

GPL1355

Series:

GSE12196

24 Samples

Download data: CEL

Analysis of calyx of Held globular bushy cells at different maturation stages: P3, P8 and P21. Calyx of Held presynaptic terminals in the auditory brainstem develop into axosomatic synapses. Results provide insight into mechanisms underlying development of mammalian synaptic structure and function.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 3 cell type, 3 development stage sets

Platform:

GPL1355

Series:

GSE49599

20 Samples

Download data: CEL

Analysis of hepatic stellate cells (HSCs) cultured with LPS for 1, 3, 6, 12, 24 hr. During exposure to toxins such as LPS, the liver suffers inflammatory injury. Results provide insight into molecular mechanisms underlying hepatic inflammatory and immune responses.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 5 time sets

Platform:

GPL1355

Series:

GSE49980

11 Samples

Download data: CEL

Analysis of hepatic stellate cells (HSCs) cultured with LPS for 1 and 24 hr. During exposure to toxins such as LPS, the liver suffers inflammatory injury. Results provide insight into molecular mechanisms underlying hepatic inflammatory and immune responses.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 2 time sets

Platform:

GPL1355

Series:

GSE49980

8 Samples

Download data: CEL

Analysis of oligodendroglia stably expressing α-synuclein and transiently expressing p25α for up to 16 hrs. Coexpression of α -synuclein and p25α causes a degenerative phenotype modeling multiple system atrophy (MSA). Results provide insight into the molecular basis of MSA pathogenesis.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 protocol, 3 time sets

Platform:

GPL1355

Series:

GSE51781

12 Samples

Download data: CEL

Analysis of livers of Sprague-Dawley animals following consumption of water containing 0.7 mM dissolved molecular hydrogen for 4 weeks. Molecular hydrogen is an antioxidant. Results provide insight into the molecular response of the liver to hydrogen saturated water.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL1355

Series:

GSE26363

8 Samples

Download data: CEL, CHP

Analysis of left lung bronchi from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 agent, 4 dose sets

Platform:

GPL1355

Series:

GSE50254

25 Samples

Download data: CEL

Analysis of left lung parenchyma from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 agent, 4 dose sets

Platform:

GPL1355

Series:

GSE50254

25 Samples

Download data: CEL

Analysis of nasal epithelia from males that were nose-only exposed for 28 days to smoke from reference cigarette 3R4F at doses up to 23ug nicotine/l or from a modified risk tobacco product (MRTP) at a dose of 23ug nicotine/l. Results provide insight into the reduced biological activity of MRTP.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 agent, 4 dose sets

Platform:

GPL1355

Series:

GSE50254

25 Samples

Download data: CEL

Analysis of livers collected from postnatal day (PND) 22 and 13-week-old Wistar/Han rats exposed in utero to polybrominated diphenyl ether (PBDE) and directly dosed with PBDE. PBDEs are flame retardants. Results provide insight into the molecular basis of PBDE toxicities.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 age, 2 agent, 2 gender sets

Platform:

GPL1355

Series:

GSE32156

30 Samples

Download data: CEL

Analysis of diencephalon from Sprague-Dawley males fed a zinc-deficient diet for 10 days then a control diet for 6 days. The zinc recovery restored food intake behaviors and salt preferences. Results provide insight into the molecular effects of short-term zinc deficiency and recovery on the brain.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 growth protocol sets

Platform:

GPL1355

Series:

GSE31430

8 Samples

Download data: CEL, CHP

Analysis of sciatic nerve from 3 week-old male Wistar pups treated daily with acrylamide (30 mg/kg) for 21 days. Acrylamide is a type-2 alkene monomer with established human neurotoxic effects. Results provide insight into the molecular basis of acrylamide neurotoxicity in developing nervous tissue.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL1355

Series:

GSE29004

4 Samples

Download data: CEL, CHP

Analysis of spinal cord from 3 week-old male Wistar pups treated daily with acrylamide (30 mg/kg) for 21 days. Acrylamide is a type-2 alkene monomer with established human neurotoxic effects. Results provide insight into the molecular basis of acrylamide neurotoxicity in developing nervous tissue.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL1355

Series:

GSE29004

4 Samples

Download data: CEL, CHP

Analysis of MH1C1 liver cells exposed to 160 or 310 uM cobalt chloride. Cobalt (Co) is a heavy metal found naturally in low concentrations and used in military and industrial applications. Co exposure can result in adverse health effects. Results provide insight into the mechanisms of Co toxicity.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 agent, 3 dose sets

Platform:

GPL1355

Series:

GSE51207

12 Samples

Download data: CEL

Analysis of H4IIEC3 liver cells exposed to 29 or 62 uM cobalt chloride. Cobalt (Co) is a heavy metal found naturally in low concentrations and used in military and industrial applications. Co exposure can result in adverse health effects. Results provide insight into the mechanisms of Co toxicity.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 agent, 3 dose sets

Platform:

GPL1355

Series:

GSE51207

12 Samples

Download data: CEL

Analysis of hippocampi of Sprauge-Dawley males for up to 168 hours following exposure to the acetylcholinesterase inhibitor soman. Soman is a potent neurotoxicant. Results provide insight into the molecular pathogenesis of soman-induced neurodegeneration.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 agent, 10 time sets

Platform:

GPL1355

Series:

GSE13428

38 Samples

Download data: CEL