GEO DataSets

Analysis of hippocampi from F344 males, at 5 age points across the adult lifespan, tested on the Morris water maze (MWM) task. MWM is a dorsal hippocampal-dependent, spatial memory task. MWM performance showed an age effect. Results provide insight into the molecular basis of cognitive aging.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 5 age sets

Platform:

GPL341

Series:

GSE9990

49 Samples

Download data: CEL

Analysis of lungs of diabetic animals. Diabetes induced by streptozotocin treatment. Results provide insight into the impact of diabetes on the cellular and molecular processes in the lung.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 disease state sets

Platform:

GPL341

Series:

GSE15900

12 Samples

Download data: CEL

Analysis of 3 tissue types from lean and insulin resistant, obese Zucker rats untreated or treated with 1 of 4 PPARγ ligands (pioglitazone, rosiglitazone, troglitazone, AG035029). Results provide insight into the role of PPARγ as an essential mediator for maintenance of body insulin sensitivity.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 5 agent, 2 genotype/variation, 3 tissue sets

Platform:

GPL341

Series:

GSE21329

54 Samples

Download data: CEL

Analysis of neurons from 4 brain regions: hippocampal CA1 and CA3, cerebellar CbG, and cerebral cortex. CA1 and CbG neurons are vulnerable to oxidative stress (OS), CA3 and cerebral cortex neurons resistant. Results provide insight into the molecular basis for selective neuronal vulnerability to OS.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 4 tissue sets

Platform:

GPL341

Series:

GSE7139

12 Samples

Download data: CEL

Analysis of pineal glands from Sprague-Dawley rats at mid-day (ZT7) or midnight (ZT19). Similar samples from pineal gland-specific DNF2 transgenic rats also examined. The pineal plays a vital role in vertebrate chronobiology. Results provide insight into night/day changes in pineal gene expression.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 genotype/variation, 2 time sets

Platform:

GPL341

Series:

GSE12342

12 Samples

Download data: CEL

Analysis of heart left ventricle from healthy animals exposed to diesel exhaust (DE) particles. Spontaneously hypertensive animals also examined. DE is linked to cardiovascular impairment. Results suggest DE exposure produces a hypertensive-like cardiac gene expression pattern in healthy animals.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 disease state, 2 stress sets

Platform:

GPL341

Series:

GSE9694

16 Samples

Download data: CEL, CHP

Analysis of primary cultured hepatocytes exposed to 4 uM cadmium for 3 hours. Cadmium is a potent carcinogen. Results provide insight into the molecular basis of cadmium toxicity.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL341

Series:

GSE8013

8 Samples

Download data: CEL, EXP

Analysis of adult and neonatal dorsal horns of spinal cords 7 days after spared nerve injury (SNI). SNI is a model for neuropathic pain (NP). Partial peripheral nerve injury in adults result in NP-like hypersensitivity, but not in neonates. Results provide insight into the molecular basis of NP.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 development stage, 2 protocol sets

Platform:

GPL341

Series:

GSE18803

24 Samples

Download data: CEL

Analysis of hearts of animals after subchronic exposure to zinc via nose only inhalation of aerosolized zinc sulfate (10, 30 or 100 ug zinc/m3), for 5 hours/day, 3 days/week for 16 weeks. Results provide insight into the effect of inhalation of zinc at environmentally relevant levels on the heart.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 4 dose sets

Platform:

GPL341

Series:

GSE11091

24 Samples

Download data: CEL, CHP

Analysis of normal heart left ventricle and diaphragm of young-adult Sprague Dawley males. Concurrent rhythmic contractions of the diaphragm and heart are needed to sustain life. Results provide insight into transcriptional strategies for ensuring long-term energy supplies in these two muscles.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 tissue sets

Platform:

GPL341

Series:

GSE6943

12 Samples

Download data: CEL

Analysis of testis of cryptorchid (orl) fetuses at at various gestational days up to GD19. The orl strain is at high risk for cryptorchidism, or undescended testis, one of the most common congenital anomalies in humans. Results provide insight into molecular mechanisms underlying cryptorchidism.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 age, 2 strain sets

Platform:

GPL341

Series:

GSE7755

20 Samples

Download data: CEL

Analysis of gubernaculum of cryptorchid (orl) fetuses at various gestational days up to GD20. The orl strain is at high risk for cryptorchidism, or undescended testis, one of the most common congenital anomalies in humans. Results provide insight into molecular mechanisms underlying cryptorchidism.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 age, 2 gender, 3 other, 2 strain sets

Platform:

GPL341

Series:

GSE7755

34 Samples

Download data: CEL

Analysis of heart left ventricles of diabetic animals. Diabetes induced by streptozotocin treatment. Results provide insight into the molecular mechanisms underlying diabetes-induced cardiac dysfunction.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 disease state sets

Platform:

GPL341

Series:

GSE6880

6 Samples

Download data: CEL

Analysis of brain frontal lobes of animals treated with chlorpyrifos (CPF) at doses up to 30 mg/kg. Subtoxic exposure to CPF, an organophosphorus insecticide, has long-term adverse effects on brain development. Results provide insight into the molecular mechanisms underlying these effects.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 7 dose sets

Platform:

GPL341

Series:

GSE9751

44 Samples

Download data: CEL

Anlaysis of CA1 and CA3 hippocampal slice cultures for up to 12 hours following treatment with duroquinone to induce oxidative stress (OS). Neurons in the CA1 region are sensitive to OS, while those in CA3 are resistant. Results provide insight into the molecular basis of this difference.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 4 time, 2 tissue sets

Platform:

GPL341

Series:

GSE6693

16 Samples

Download data: CEL

Analysis of livers of Wistar animals during a 24-hour period, from zeitgeber time (ZT) 0.25 to ZT 23.75. Results provide insight into baseline patterns of gene expression in normal liver within the 24 hour circadian cycle.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 18 time sets

Platform:

GPL341

Series:

GSE8988

54 Samples

Download data: CEL

Analysis of gastrocnemius muscles of Wistar animals during a 24-hour period, from zeitgeber time (ZT) 0.25 to ZT 23.75. Results provide insight into baseline patterns of gene expression in normal skeletal muscle within the 24 hour circadian cycle.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 18 time sets

Platform:

GPL341

Series:

GSE8989

54 Samples

Download data: CEL

Analysis of small diameter branches of the saphenous artery from spontaneously hypertensive (SHR) and adrenocorticotropic hormone (ACTH)-induced hypertensive animals. The saphenous artery is a resistance artery. Results provide insight molecular mechanisms contributing to hypertension.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 agent, 2 disease state, 2 strain sets

Platform:

GPL341

Series:

GSE8051

9 Samples

Download data: CEL, CHP, EXP

Analysis of male and female lungs at various time points up to 40 days post-infection with Seoul hantavirus. Males and females differ in their susceptibility to several RNA and DNA viruses. Results provide insight into the influence of gender in the response to Seoul hantavirus infections.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 gender, 2 infection, 4 time sets

Platform:

GPL341

Series:

GSE7271

24 Samples

Download data: CEL

Analysis of kidneys of Eker males treated for up to 14 days with the genotoxic carcinogen aristolochic acid (AA) or the non-genotoxic carcinogen ochratoxin A (OTA). The Eker rat, heterozygous mutant for the tuberous sclerosis 2 (Tsc2) tumor suppressor gene, is a model to study renal carcinogenesis.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 5 agent, 2 genotype/variation, 4 time sets

Platform:

GPL341

Series:

GSE5923

84 Samples

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