GEO DataSets

Analysis of muscle from patients with a mutation (Arg1174Gln) in the tyrosine kinase domain of the insulin receptor gene (INSR). This mutation is associated with inherited insulin resistance. Results provide insight into molecular mechanisms underlying insulin resistance in skeletal muscle.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL571

Series:

GSE36297

16 Samples

Download data: CEL

Analysis of 7 patients with glioblastoma (GBM) treated at Memorial Sloan-Kettering Cancer Center, with survival > 48 months. These long-term survivors (LTSs) represent proneural, neural, classical, and mesenchymal subtypes of GBM. Results provide insight into molecular characteristics of GBM LTSs.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 4 disease state, 7 individual, 7 time sets

Platform:

GPL571

Series:

GSE54077

7 Samples

Download data: CEL

Analysis of A2EN endocervical epithelial cells infected with a Chlamydia trachomatis mutant strain lacking type III secretion effector TepP (Ct875) or its complemented counterpart for 4hr. Results provide insight into the impact of effector protein TepP on the host cell molecular response.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 infection sets

Platform:

GPL571

Series:

GSE54336

6 Samples

Download data: CEL

Analysis of SF539 glioma cells depleted for PARK2. PARK2 is an E3 ubiquitin ligase. Results provide insight into the role of PARK2 in the coordinate control of cyclins in cell cycle regulation and tumor suppression.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 agent sets

Platform:

GPL571

Series:

GSE50864

6 Samples

Download data: CEL

Analysis of SNB19 glioma cells depleted for PARK2. PARK2 is an E3 ubiquitin ligase. Results provide insight into the role of PARK2 in the coordinate control of cyclins in cell cycle regulation and tumor suppression.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 agent sets

Platform:

GPL571

Series:

GSE50864

6 Samples

Download data: CEL

Analysis of ectopic endometria and eutopic endometria from endometriosis patients. Endometriosis is characterized by the presence of endometrial tissue at extra-uterine sites. Results provide insight into the molecular mechanisms underlying endometriosis pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 3 tissue sets

Platform:

GPL571

Series:

GSE25628

22 Samples

Download data: CEL

Analysis of pigmented melanoma G3361 cell line following ABCB5 ablation. ABCB5 [ATP-binding cassette, subfamily B (MDR/TAP), member 5] is a drug efflux transporter shown to be highly overexpressed in diverse human cancers. Results provide insight into the role of ABCB5 in melanoma.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL571

Series:

GSE38290

6 Samples

Download data: CEL, EXP, TXT

Analysis of nonpigmented melanoma A375 cell line following ABCB5 ablation. ABCB5 [ATP-binding cassette, subfamily B (MDR/TAP), member 5] is a drug efflux transporter shown to be highly overexpressed in diverse human cancers. Results provide insight into the role of ABCB5 in melanoma.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL571

Series:

GSE38290

6 Samples

Download data: CEL, EXP, TXT

Comparison of dendritic cells (DCs) from young (20 to 27 years) and aged (77 to 87 years) donors. DCs are antigen-presenting cells important in initiating and regulating innate and adaptive immune responses. Results provide insight into the molecular basis of the decline in DC function with age.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 age sets

Platform:

GPL571

Series:

GSE58015

9 Samples

Download data: CEL

Analysis of astrocyte and glioma cells depleted for FAT1. FAT1 encodes a cadherin-like protein. Results provide insight into the role of FAT1 in cancer development.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 cell line, 2 cell type, 2 protocol sets

Platform:

GPL571

Series:

GSE40583

18 Samples

Download data: CEL

Analysis of MDA-MB231 breast cancer cells depleted for PIAS1. PIAS1 is a SUMO ligase. Results provide insight into the role of PIAS1 in breast tumorigenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 growth protocol, 2 protocol sets

Platform:

GPL571

Series:

GSE44024

4 Samples

Download data: CEL, CHP

Analysis of A375P melanoma cells depleted for PGC1alpha. PGC1alpha is a transcriptional coactivator that promotes mitochondrial biogenesis and respiration. A375P is a cell line that overexpresses PGC1alpha. Results provide insight into the role of PGC1alpha in melanoma.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL571

Series:

GSE36879

8 Samples

Download data: CEL

Analysis of A673 Ewing Sarcoma cell line for up to 96hrs after inducible EWSR1/FLI1 knockdown. Oncogenic ETS fusions are driver mutations in diverse cancers, including Ewing sarcoma. Results provide insight into the molecular mechanisms underlying ETS-driven tumorigenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 protocol, 6 time sets

Platform:

GPL571

Series:

GSE27524

16 Samples

Download data: CEL

Analysis of discoid lupus erythematosus (DLE) and psoriasis skin samples. DLE is the most common skin manifestation of lupus; psoriasis is the most well-characterized autoimmune skin disease to date. Results provide insight into the molecular mechanisms underlying DLE skin.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 disease state, 2 other sets

Platform:

GPL571

Series:

GSE52471

38 Samples

Download data: CEL

Analysis of EVCTs isolated from first trimester placenta and treated with rosiglitazone, a PPARγ agonist. EVCT invasion into the uterus is critical for placental and fetal development. Results provide insight into the molecular basis of PPARγ-mediated regulation of EVCT invasion in vitro.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL571

Series:

GSE28426

10 Samples

Download data: CEL

Analysis of marrow-infiltrating CD3+ T cells isolated from relapsed chronic myelogenous leukemia (CML) patients following donor lymphocyte infusion (DLI) therapy. Four patients were DLI-responsive, two were DLI-nonresponsive. Results provide mechanistic insights into DLI response in relapsed CML.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 individual, 2 protocol sets

Platform:

GPL571

Series:

GSE49067

12 Samples

Download data: CEL

Analysis of LNCaP prostate cancer cells overexpressing the Mediator of RNA polymerase II transcription factor 1 (MED1). MED1 is a coactivator of the androgen receptor and other signal-activated transcription factors. Results provide insight into the role of MED1 overexpression in prostate cancer.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL571

Series:

GSE41150

4 Samples

Download data: CEL

Analysis of non-lesional (NL) skin of psoriasis patients 24 hrs after a single intradermal injection of interferon-γ (IFN-γ) to the NL skin. Results suggest that IFN-γ may prime an inflammatory environment in the skin that shares many features with psoriasis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 20 individual, 3 protocol, 2 time sets

Platform:

GPL571

Series:

GSE32407

60 Samples

Download data: CEL

Analysis of skin samples from 4 responding patients who relapsed following efalizumab treatment for psoriasis: baseline non-lesional and lesional samples; week 12 post-treatment and relapse samples. Results provide insight into molecular mechanisms underlying post-therapeutic relapse of psoriasis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 4 disease state, 4 individual, 2 time sets

Platform:

GPL571

Series:

GSE30768

14 Samples

Download data: CEL

Analysis of an in vitro model of peptidoglycan-activated monocytes as inflammatory myeloid dendritic cells (DCs). DCs are thought to have an important role in the pathogenesis of inflammatory skin lesions such as psoriasis. Results provide insight into molecular basis of psoriasis pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 5 agent sets

Platform:

GPL571

Series:

GSE42305

15 Samples

Download data: CEL