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Links from GEO DataSets

Items: 20

1.
Full record GDS1334

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133B)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL97
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1334
ID:
1334
2.

Effect of Oxandrolone on Muscle in Duchenne Muscular Dystrophy

(Submitter supplied) Three subjects with Duchenne muscular dystrophy (8.3, 10.4, and 16.7 years old) were studied. Baseline studies included stable isotope infusion followed by gastrocnemius muscle biopsy to determine myosin heavy chain synthesis rates. RNA was isolated from the muscle biopsy as well. The subjects were then treated for 3 months with oxandrolone (a synthetic anabolic steroid, 0.1 mg/kg/day) and the studies repeated. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS1333 GDS1334
Platforms:
GPL96 GPL97
12 Samples
Download data
Series
Accession:
GSE1764
ID:
200001764
3.
Full record GDS1333

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133A)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL96
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1333
ID:
1333
4.

Muscle, normal extraocular, profile

(Submitter supplied) Molecular definition of human extraocular muscles (EOM). Human EOM were compared with limb (quadriceps femoris) muscle. Keywords = Eye Keywords = EOM Keywords = Muscle Keywords = DMD Keywords = Myasthenia Gravis Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS525
Platform:
GPL96
5 Samples
Download data: CEL
Series
Accession:
GSE873
ID:
200000873
5.
Full record GDS525

Extraocular and limb muscle comparison

Molecular definition of extraocular muscle (EOM). Autopsy superior rectus EOM compared with biopsy limb quadriceps femoris muscle.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL96
Series:
GSE873
5 Samples
Download data: CEL
DataSet
Accession:
GDS525
ID:
525
6.

A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL9454 GPL570
65 Samples
Download data: CEL
Series
Accession:
GSE35661
ID:
200035661
7.

Time course Healthy DMD myogenesis

(Submitter supplied) Primairy human myoblast cell cultures Healthy DMD Keywords: time-course
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL2097
42 Samples
Download data
Series
Accession:
GSE2693
ID:
200002693
8.

Effect of facioscapulohumeral dystrophy (FSHD) on skeletal muscle gene expression

(Submitter supplied) Muscle biopsies taken from vastus lateralis muscle of 30 normal subjects and 19 FSHD subjects (see PubMed ID 17151338) Affymetrix U133A and U133B arrays were scanned both before (S1) and after (S2) antibody enhancement. Effects of age and sex in normal subjects reported previously under GSE362, GSE674, and GSE9676. Keywords: facioscapulohumeral dystrophy, skeletal muscle
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL96 GPL97
196 Samples
Download data: CEL
Series
Accession:
GSE10760
ID:
200010760
9.

Effect of acute creatine monohydrate supplementation on skeletal muscle transcriptome

(Submitter supplied) Expression profiling of vastus lateralis muscle of young, healthy, non-obese men supplemented with creatine monohydrate vs. placebo for 10 days. Results identify transcriptional pathways activated in skeletal muscles as a result of acute creatine monohydrate supplementation. Keywords: Supplementation response.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5216
12 Samples
Download data: GPR
Series
Accession:
GSE7877
ID:
200007877
10.

Innervated and 2 month Denervated Rat EDL muscles

(Submitter supplied) The right legs of 8 Brown-Norway male rats were denervated by a high sciatic nerve section in the hip region of the hind limb.Two months after denervation (6 months of age), extensor digitorum longus (EDL) muscles were removed from the operated legs. The EDL muscles from 8 age-matched non-operated rats served as innervated controls. Total RNA was isolated, labeled cDNA was prepared and hybridized to the Rat Atlas 1.2 Array II membranes (Clontech Laboratories, Palo Alto, CA). more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL154
16 Samples
Download data
Series
Accession:
GSE1741
ID:
200001741
11.

Normal human muscle - U133 arrays

(Submitter supplied) vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old) Keywords = muscle Keywords = aging Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS287 GDS288
Platforms:
GPL96 GPL97
30 Samples
Download data
Series
Accession:
GSE362
ID:
200000362
12.
Full record GDS288

Muscle function and aging - male (HG-U133B)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL97
Series:
GSE362
15 Samples
Download data
DataSet
Accession:
GDS288
ID:
288
13.
Full record GDS287

Muscle function and aging - male (HG-U133A)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL96
Series:
GSE362
15 Samples
Download data
DataSet
Accession:
GDS287
ID:
287
14.

Molecular profiles (HG-U95A) of dystrophin-deficient and normal human muscle

(Submitter supplied) Molecular profiles of dystophin-deficient patients and normal human skeletal muscles on Affymetrix HG-U95A arrays Keywords = DMD Keywords = Duchenne muscular dystrophy Keywords = dystrophin Keywords = Affymetrix U95A array Keywords = skeletal muscle Keywords = gene expression profiles Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS563
Platforms:
GPL8300 GPL91
24 Samples
Download data: CEL, EXP, RPT
Series
Accession:
GSE1004
ID:
200001004
15.
Full record GDS563

Duchenne muscular dystrophy (II) (HG-U95A)

Search for modifying factors and pathogenic pathways involved in Duchenne muscular dystrophy (DMD). Quadricep skeletal muscle biopsies from 12 DMD patients and 11 unaffected control patients examined.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL8300
Series:
GSE1004
23 Samples
Download data: CEL, EXP, RPT
16.

Laminin-deficient muscular dystrophy, dy/dy diaphragm

(Submitter supplied) Laminin (merosin) deficient muscular dystrophy in dy/dy mouse diaphragm muscle, 8 weeks old Keywords: muscle, muscular dystrophy, laminin, merosin, diaphragm, mouse
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS1778
Platform:
GPL339
8 Samples
Download data
Series
Accession:
GSE3252
ID:
200003252
17.
Full record GDS1778

Alpha2-laminin deficient dy/dy model of muscular dystrophy: diaphragm

Analysis of diaphragms of alpha2-laminin deficient dy/dy animals. Alpha-2 laminin is important in muscle cell attachment, and its deficiency underlies classical congenital muscular dystrophy. Results provide insight into the events that link alpha2-laminin deficiency with muscle fiber necrosis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL339
Series:
GSE3252
8 Samples
Download data
DataSet
Accession:
GDS1778
ID:
1778
18.

Comparative profiling in 13 muscle disease groups

(Submitter supplied) Summary: Genetic disorders of muscle cause muscular dystrophy, and are some of the most common inborn errors of metabolism. Muscle also rapidly remodels in response to training and innervation. Muscle weakness and wasting is important in such conditions as aging, critical care medicine, space flight, and diabetes. Finally, muscle can also be used to investigate systemic defects, and the compensatory mechansisms invoked by cells to overcome biochemical and genetic abnormalities. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS1956 GDS2855
Platforms:
GPL97 GPL96
242 Samples
Download data: CEL
Series
Accession:
GSE3307
ID:
200003307
19.
Full record GDS2855

Various muscle diseases (HG-U133B)

Analysis of muscle biopsy specimens from patients with various muscle diseases. Results provide insight into the diagnosis and pathogenesis of muscle diseases.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 11 disease state sets
Platform:
GPL97
Series:
GSE3307
119 Samples
Download data: CEL
20.
Full record GDS1956

Various muscle diseases (HG-U133A)

Analysis of muscle biopsy specimens from patients with various muscle diseases. Results provide insight into the diagnosis and pathogenesis of muscle diseases.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 12 disease state sets
Platform:
GPL96
Series:
GSE3307
121 Samples
Download data: CEL
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