GEO DataSets

(Submitter supplied) Analysis of peripheral blood mononuclear cells (PBMCs) separated from whole blood of healthy male subjects - prior to onset of exercise - immediately following the end of exercise and - immediately following 1 hour of recovery from exercise Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS962

Platform:

GPL96

15 Samples

Download data: CEL

Peripheral blood mononuclear cells (PBMC) were isolated from blood samples taken from healthy male subjects before, immediately after, and 60 minutes after 30 minutes of exercise. Brisk activation and deactivation of genes associated with stress, inflammation, and tissue repair observed.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 time sets

Platform:

GPL96

Series:

GSE1140

15 Samples

Download data: CEL

(Submitter supplied) Relatively brief bouts of exercise alter gene expression in peripheral blood mononuclear cells (PBMCs), but whether or not exercise changes gene expression in circulating neutrophils (whose numbers, like PBMCs, increase) is not known. We hypothesized that exercise would activate neutrophil genes involved in apoptosis, inflammation, and cell growth and repair, since these functions in leukocytes are known to be influenced by exercise. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3073

Platform:

GPL570

24 Samples

Download data: CEL

Analysis of neutrophils from healthy males before and after 30 minutes of aerobic exercise. The number of circulating neutrophils increases after exercise. Results provide insight into the molecular response of these immune cells to exercise.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 12 individual, 2 protocol sets

Platform:

GPL570

Series:

GSE8668

24 Samples

Download data: CEL

(Submitter supplied) There is an association between transcriptome and the exercise-related phenotype. Peripheral blood cells suffer alterations in the gene expression pattern in response to perturbations caused by exercise. The acute response to endurance activates stress and inflammation, as well as growth and tissue repair responses. Peripheral blood mononuclear cell (PBMC) samples were obtained at baseline and after an endurance training protocol from healthy male untrained police recruits. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6244

26 Samples

Download data: CEL

(Submitter supplied) We compared PBMC genomic response to exercise in both early (EG) and late-pubertal girls (LG) Keywords: stress response

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

40 Samples

Download data: CEL

(Submitter supplied) White blood cells (WBCs) express tens of thousands of genes. Their expression levels are modified by genetic and external factors. The purpose of the present study was to investigate the effects of acute exercise on gene expression profiles (GEPs) of WBCs and to identify suitable genes which may serve as surrogate markers for monitoring exercise and training load. Five male probands performed an exhaustive treadmill test (ET) at 80% of their VO2max, and a moderate treadmill test (MT) at 60% VO2max for exactly the same time one to two week later. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2310

Platform:

GPL571

20 Samples

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Analysis of white blood cells (WBCs) from 5 males following exhaustive or moderate exercise. Results provide insight into the effects of exercise at the molecular level and the feasibility of using gene expression profiles of WBCs to monitor exercise and training load.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 5 individual, 4 time sets

Platform:

GPL571

Series:

GSE3606

20 Samples

Download data

(Submitter supplied) cDNA microarray screening for gene expression changes in peripheral blood of eight half-marathon runners before (time point 0), immediately (time point 1) after and 24 h (time point 2) after exercise for details see publication: ... Keywords: repeat sample

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1962

8 Samples

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(Submitter supplied) The immunological reaction to exercise has been investigated with increasing intensity in the last 10-20 years, with most human studies performed in male subjects. Recently, gender-specific aspects have received growing attention, but studies carefully monitoring the influence of gender, including the menstrual cycle, are rare. Here, we report gene expression patterns in response to a run at 93% of the individual anaerobic threshold of 9 women with regular menstrual cycles and no use of oral contraceptives who ran both at day 10 (follicular phase, F) and at day 25 (luteal phase, L) of their cycle. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL5676

6 Samples

Download data: TXT

(Submitter supplied) Study goal is to disclose features of gene expressio profile of non-cancerous liver-infiltrating lymphocytes of type C hepatitis patients with hepatocellular carcinomas and tumor-infiltrating lymphocytes of type C hepatitis patients with hepatocellular carcinomas. Keywords: gene expression profile, non-cancerous liver-infiltrating lymphocytes, tumor-infiltrating lymphocytes, type C hepatitis, hepatocellular carcinoma

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1291

24 Samples

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(Submitter supplied) Study goal is to disclose features of gene expression profile of peripheral blood mononuclear cells obtained from type C cirrhotic patients with or without hepatocellular carcinomas. Keywords: gene expression profile, peripheral blood mononuclear cells, type C liver cirrhosis

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1291

62 Samples

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(Submitter supplied) Biotinylated cRNA was synthesized from total RNA (Enzo; Farmingdale, NY) and processed according to the Affymetrix GeneChip Expression Analysis Technical Manual (Affymetrix; Santa Clara, CA). 57 samples: 5 pauciarticular PBMC, 15 polyarticular PBMC, 11 control PMBC, 6 JSpA PBMC, 5 pauciarticular SFMC, 10 polyarticular PBMC, 5 JSpA SFMC classified by course. Keywords = juvenile rheumatoid arthritis (JRA) Keywords = peripheral blood mononuclear cells (PBMC) Keywords = synovial fluid mononuclear cells (SFMC) Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS711

Platform:

GPL8300

57 Samples

Download data: CEL

Examination of peripheral blood and synovial fluid mononuclear cells in pauciarticular and polyarticular rheumatoid arthritis, and in juvenile spondyloarthropathy. Results identify disease subtypes and provide insight into disease mechanisms.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 cell type, 4 disease state sets

Platform:

GPL8300

Series:

GSE1402

57 Samples

Download data: CEL

(Submitter supplied) We compared PBMC genomic response to exercise in both early (EB) and late-pubertal boys (LB) Keywords: stress response

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

40 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array; Expression profiling by array

Platforms:

GPL10850 GPL570

46 Samples

Download data: CEL, TXT

(Submitter supplied) We tested the hypothesis on the mechanisms responsible for the early control of NK cell function by identifying a discrete set of genes in circulating NK cells that were altered by exercise. Exercise leads to a rapid change in the profile of gene expression in NK cells.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

24 Samples

Download data: CEL

(Submitter supplied) Exercise leads to a rapid change in the profile of gene expression in NK cells. We hypothesized that microRNA expression in circulating NK cells would also be affected by brief exercise.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL10850

22 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL570 GPL10850

48 Samples

Download data: CEL, TXT

(Submitter supplied) Exercise leads to a rapid change in the profile of gene expression in monocytes. We hypothesized that microRNA expression in circulating monocytes would also be affected by brief exercise.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL10850

24 Samples

Download data: TXT