GEO DataSets

(Submitter supplied) Gene expression test data set from rat blood samples exposed to either 150, 1500 or 2000 mg/kg of APAP for 3, 6 or 24 hours. The Supplementary file (appended below) contains the mapping for the decoding of blinded samples. Keywords: Dose response, Time course, Microarray, Gene expression

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL890

144 Samples

Download data: TXT

(Submitter supplied) The Supplementary files (appended below) contain the mapping for the decoding of blinded samples. This SuperSeries is composed of the SubSeries listed below.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL890

356 Samples

Download data: TXT

(Submitter supplied) Gene expression test data set from rat liver samples exposed to either 150, 1500 or 2000 mg/kg of APAP for 3, 6 or 24 hours. The Supplementary file (appended below) contains the mapping for the decoding of blinded samples. Keywords: Dose response, Time course, Microarray, Gene expression

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL890

144 Samples

Download data: TXT

(Submitter supplied) Gene expression training data set from rat blood samples exposed to either 150, 1500 or 2500 mg/kg of APAP for 6, 12 or 24 hours. Keywords: Dose response, Time course, Microarray, Gene expression

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL890

68 Samples

Download data

(Submitter supplied) Preclinical biomarkers useful for identification of idiosyncratic drugs have not been identified. It is hypothesized that patterns of transcript expression for the hepatotoxicants, including classical and idiosyncratic hepatotoxicants, are similar and the patterns differ from those of non-hepatotoxicants. This experiment is part of the biomarkers study, and focus on two clasical hepatotoxicants: Acetaminophen and Carbon tetrachloride. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL4135

96 Samples

Download data: TXT

(Submitter supplied) Predose and postdose gene expression profiles of blood samples of five most susceptible and five most resistant rats to acetaminophen-induced hapatotoxicity were determined by microarray analysis. Four out of ten selected genes were found to be reproducibly in real-time PCR with independent set animals to predict the susceptible individuals to acetaminophen-induced hapatotoxicity.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL1355

20 Samples

Download data: CEL