GEO DataSets

(Submitter supplied) Some studies have shown that acute intake of high-phenol virgin olive oil reduces pro-inflammatory, pro-oxidant and pro-thrombotic states, but nowadays still remains unclear if those effects attributed to its phenolic fraction could be exerted at transcriptional level in vivo. Two virgin olive oil-based breakfasts with high (398 ppm) and low (70 ppm) content of phenolic compounds were administered to twenty patients (9 men and 11 women) with metabolic syndrome following a double-blinded random crossover design. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL4133

80 Samples

Download data: TXT

(Submitter supplied) Gene expression profiles of PBMCs in patients with MS following extra virgin olive oil intake. The aim of the present study was to investigate the whole-genome gene and miRNA profiles of after EVOO intake. Results provide the information of changes in PBMCs transcriptome following EVOO intake.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL10558

24 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL8179 GPL10558

72 Samples

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(Submitter supplied) miRNA expression profiles of PBMCs in healthy subjects following extra virgin olive oil intake. The aim of the present study was to investigate the whole-genome gene and miRNA profiles of PBMCs after EVOO intake. Results provide the information of changes in PBMPs transcriptome following EVOO intake.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL8179

24 Samples

Download data: TXT

(Submitter supplied) Gene expression profiles of PBMCs in healthy subjects following extra virgin olive oil intake. The aim of the present study was to investigate the whole-genome gene and miRNA profiles of after EVOO intake. Results provide the information of changes in PBMPs transcriptome following EVOO intake.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL10558

24 Samples

Download data: TXT

(Submitter supplied) Despite the benefits associated with healthy diets, data on the mechanisms by which these benefits are promoted are scarce. Our aim was to explore the global transcriptomic response of biological pathways related to cardiovascular disease associated with traditional Mediterranean diet (TMD) intervention. The PREDIMED study is a large on-going, parallel, multicentre, randomised, controlled trial aimed at assessing the TMD effect on primary cardiovascular prevention. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL571

65 Samples

Download data: CEL

(Submitter supplied) Olive oil is protective against risk factors for cardiovascular and cancer diseases. A nutrigenomic approach was performed to assess whether olive oil, the main fat of the Mediterranean diet modifies the gene expression in human peripheral blood mononuclear cells. Six healthy male volunteers ingested, at fasting state, 50 ml of olive oil, and continued with the same olive oil as a source of raw fat (25ml/day) during 3 weeks. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3691

Platform:

GPL6511

9 Samples

Download data: TXT

(Submitter supplied) see manufacturer's web site https://products.appliedbiosystems.com/ab/en/US/adirect/ab;jsessionid=HyNBrYvlwy6ncF1Kn3KVLSLwlbXWyxZLRyZJthLvtFdht7vG2L2T!161467451?cmd=catProductDetail&productID=4359030&catID=602388&backButton=true

Organism:

Homo sapiens

1 DataSet

1 Series

9 Samples

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Analysis of PBMCs from healthy males after 3 weeks of virgin olive oil (VOO) consumption at doses common in the Mediterranean diet. The Mediterranean diet protects against cardiovascular diseases. Results provide insight into the molecular mechanisms underlying the beneficial action of VOO.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 protocol, 3 time sets

Platform:

GPL6511

Series:

GSE10590

9 Samples

Download data: TXT

(Submitter supplied) The acute response four hours after a fat load of extra virgin olive oil was investigated using DNA microarrays. Hepatic gene expression was analysed in Wistar Rats.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL1355

2 Samples

Download data: CEL

(Submitter supplied) Gene expression in peripheral blood is shown sufficient to differentiate patients with metabolic disorders from control. The signatures of metabolic syndrome, coronary artery disease and type 2 diabetes also have significant overlap.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL10775

35 Samples

Download data: GPR

(Submitter supplied) Whole genome transcriptional profiling was used to characterize the response of Lactobacillus plantarum WCFS1 human isolate during challenge with olive oil (OO). Twelve independent experiments were performed and mixed at random in groups of four for total of three RNA samples. The transcriptional profile reveals the downregulation of processes associated with rapid growth and the induction of stress-related pathways indicating the involvement of the stringent response. more...

Organism:

Lactiplantibacillus plantarum WCFS1; Lactiplantibacillus plantarum

Type:

Expression profiling by array

Platform:

GPL15934

3 Samples

Download data: TXT

(Submitter supplied) Adequate intake of protein among older adults is associated with better health outcomes, but conflicting results makes it difficult to define the optimal intake. To further understand the impact of protein intake on metabolic processes we studied genome-wide gene expression changes in peripheral blood mononuclear cells (PBMCs) in home-dwelling old subjects after increased protein intake for 12 weeks.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL10558

62 Samples

Download data: TXT