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Links from GEO DataSets

Items: 11

1.

Transcriptome comparison of B. anthracis Ames and isogenic sinR-null mutant, UTA21

(Submitter supplied) To establish the SinR regulon in B. anthracis, gene expression of the fully virulent Ames strain and the isogenic sinR-null strains were compared using expression microarray analysis.
Organism:
Bacillus anthracis
Type:
Expression profiling by array
Platform:
GPL10581
12 Samples
Download data: CEL
Series
Accession:
GSE22559
ID:
200022559
2.

Identification of the genes regulated by YvfI transcriptional factor

(Submitter supplied) Genome-wide comparative transcriptome analysis of the Bacillus subtilis parent strain PY79 and its yvfI derivative with yvfI::T10::spc (TEK1) grown in PA medium Detailed description of sample preparation and microarray conditions can be also found in Irigul et al to be submitted
Organism:
Bacillus subtilis
Type:
Expression profiling by array
Platform:
GPL6031
3 Samples
Download data: TXT
Series
Accession:
GSE34414
ID:
200034414
3.

Undomesticated Bacillus subtilis RemA regulon

(Submitter supplied) Transcriptional profiling of Bacillus subtilis str 3610 cells comparing sinR-/epsH- cells to sinR-/epsH-/remA- cells in MSgg Medium at optical density (600nm) of 1.0
Organism:
Bacillus subtilis
Type:
Expression profiling by array
Platform:
GPL15179
3 Samples
Download data: TXT
Series
Accession:
GSE47409
ID:
200047409
4.

The sigmaB regulon of B. cereus ATCC14579

(Submitter supplied) The alternative sigma factor sigmaB has an important role in the acquisition of stress-resistance in many gram-positive bacteria. In the foodborne pathogen Bacillus cereus sigmaB is activated strongly upon a heat shock and other stress conditions. Here we describe the identification of the set of sigmaB-regulated genes in B. cereus by DNA microarray analysis of the transcriptome upon a mild heat shock. more...
Organism:
Bacillus cereus ATCC 14579
Type:
Expression profiling by array
Platform:
GPL4406
7 Samples
Download data
Series
Accession:
GSE6005
ID:
200006005
5.

A new Rrf2 repressor family member, SaiR, controls transcription of spxA2 encoding a regulator of the oxidative stress response in Bacillus anthracis.

(Submitter supplied) Spx, a member of the ArsC (arsenate reductase) protein family, is highly conserved in Gram-positive bacteria, where it interacts with RNA polymerase to activate transcription in response to toxic oxidants.  In Bacillus anthracis, resistance to oxidative stress requires the activity of two paralogous forms of Spx, SpxA1 and SpxA2.   Suppressor mutations were identified in spxA1 mutant cells that conferred resistance to hydrogen peroxide. more...
Organism:
Bacillus anthracis
Type:
Expression profiling by array
Platform:
GPL10189
6 Samples
Download data: MEV
Series
Accession:
GSE57851
ID:
200057851
6.

The YmdB phosphodiesterase is a global regulator of biofilm-specific mRNA levels in Bacillus subtilis

(Submitter supplied) Detailed description (other than provided below) of growth conditions, RNA preparation, cDNA synthesis and hybridization conditions can be found in the submitted paper.
Organism:
Bacillus subtilis
Type:
Expression profiling by array
Platform:
GPL6031
16 Samples
Download data: TXT
Series
Accession:
GSE39142
ID:
200039142
7.

A Bacillus anthracis RNA binding protein post-transcriptionally regulates two component signaling through RNA turnover

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Bacillus anthracis
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL31186
20 Samples
Download data
Series
Accession:
GSE193212
ID:
200193212
8.

A Bacillus anthracis RNA binding protein post-transcriptionally regulates two component signaling through RNA turnover [RIP-Seq]

(Submitter supplied) Formaldehyde cross-linking RNA immunoprecipitation coupled with illumina sequencing (fRIP-seq) was performed to pinpoint the direct RNA targets of KrrA using a FLAG-tagged KrrA construct that is driven by a constitutive promoter Plgt (pOS1.PlgtkrrA-FLAG).
Organism:
Bacillus anthracis
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL31186
8 Samples
Download data: XLSX
Series
Accession:
GSE193211
ID:
200193211
9.

A Bacillus anthracis RNA binding protein post-transcriptionally regulates two component signaling through RNA turnover [RNA-Seq]

(Submitter supplied) To uncover the effects of KrrA regulation on gene transcription and define the bacterial response imposed by this regulation, a transcriptomic study was carried out in which Bacillus anthracis krrA was compared to WT in two growth conditions: LB in the presence or absence of ‘205.
Organism:
Bacillus anthracis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL31186
12 Samples
Download data: XLSX
Series
Accession:
GSE193210
ID:
200193210
10.

The cold-induced two-component system CBO0366/CBO0365 regulates metabolic pathways with novel roles in cold tolerance of Group I Clostridium botulinum ATCC 3502

(Submitter supplied) The two-component system CBO0366/CBO0365 was recently demonstrated to have a role in cold tolerance of Group I Clostridium botulinum ATCC 3502. The mechanisms under its control, ultimately resulting in increased sensitivity to low temperature, are unknown. A transcriptomic analysis with DNA microarrays was performed to identify the differences in global gene expression patterns of the wild-type ATCC 3502 and a derivative mutant with insertionally inactivated cbo0365 at 37 °C and 15 °C. more...
Organism:
Clostridium botulinum A str. ATCC 3502
Type:
Expression profiling by array
Platform:
GPL11441
6 Samples
Download data: GPR
Series
Accession:
GSE26587
ID:
200026587
11.

Improving gene set enrichment analysis (GSEA) by using regulation directionality

(Submitter supplied) To infer the biological meaning from transcriptome data, it is useful to focus on genes that are regulated by the same regulator, i.e., regulons. Unfortunately, current gene set enrichment analysis (GSEA) tools do not consider whether a gene is activated or repressed by a regulator. This distinction is crucial when analyzing regulons since a regulator can work as an activator of certain genes and as a repressor of other genes, yet both sets of genes belong to the same regulon. more...
Organism:
Bacillus subtilis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28092
4 Samples
Download data: TXT
Series
Accession:
GSE208571
ID:
200208571
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