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Links from GEO DataSets

Items: 10

1.

Molecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity (set 2)

(Submitter supplied) In this study we have analyzed gene expression and metabolite levels in the livers of male and female Zucker diabetic fatty (ZDF) rats. We speculated that the sex different development of diabetes in the ZDF animals presents the opportunity to relate gender to diabetes (since only males become diabetic on normal diet). In this model one can search for parameters that distinguish females fed normal diet compared to high fat diet (i.e. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL6528
4 Samples
Download data: GPR
Series
Accession:
GSE23809
ID:
200023809
2.

Molecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL6528
8 Samples
Download data: GPR
Series
Accession:
GSE23810
ID:
200023810
3.

Molecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity (set 1)

(Submitter supplied) In this study we have analyzed gene expression and metabolite levels in the livers of male and female Zucker diabetic fatty (ZDF) rats. We speculated that the sex different development of diabetes in the ZDF animals presents the opportunity to relate gender to diabetes (since only males become diabetic on normal diet). In this model one can search for parameters that distinguish females fed normal diet compared to high fat diet (i.e. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL6528
4 Samples
Download data: GPR
Series
Accession:
GSE23808
ID:
200023808
4.

Zucker diabetic fatty (ZDF)/Zucker lean control (ZLC) comparisons

(Submitter supplied) Gene expression profiles in tissues of Zucker diabetic fatty (ZDF) rats compared with age matched Zucker lean control (ZLC) rats. Keywords: other
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS1767
Platform:
GPL1002
24 Samples
Download data
Series
Accession:
GSE1080
ID:
200001080
5.
Full record GDS1767

Zucker diabetic fatty model of type 2 diabetes: various insulin-sensitive tissues

Analysis of adipose, skeletal muscle, and liver tissues of Zucker diabetic fatty animals at pre-diabetic and diabetic stages. ZDF animals have a mutated leptin receptor. Results provide insight into the molecular mechanisms responsible for insulin resistance and progression to type 2 diabetes.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, log ratio, 2 age, 3 tissue sets
Platform:
GPL1002
Series:
GSE1080
24 Samples
Download data
DataSet
Accession:
GDS1767
ID:
1767
6.

Fat-type specific effects of high fat diets

(Submitter supplied) High fat diet (HF) rodent models have contributed significantly to the dissection of the pathophysiology of the insulin resistance syndrome, but their phenotype varies distinctly between different studies. Here, we have analyzed gene expression patterns in livers of animals fed with different HF with varying fatty acid compositions. Keywords: diet-gene interaction
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS1307
Platform:
GPL1355
10 Samples
Download data
Series
Accession:
GSE3512
ID:
200003512
7.
Full record GDS1307

Various high fat diets effect on liver

Expression profiling of liver from Wistar males fed for 12 weeks with one of 4 different high fat diets, each differing in fatty acid composition. The different fat sources used were lard, olive oil, coconut fat, and cod liver oil.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 5 protocol sets
Platform:
GPL1355
Series:
GSE3512
10 Samples
Download data
DataSet
Accession:
GDS1307
ID:
1307
8.

Characterization of genome-wide transcriptional changes in liver and adipose tissues of ZDF (fa/fa) rats fed R-α-lipoic acid by next-generation sequencing

(Submitter supplied) We report on the characterization of lipogenic tissue transcriptional networks that support physiological responses of obese rats to a lipid-lowering bioactive food compound, R-a-lipoic acid (LA). Nine-week old male ZDF (fa/fa) rats were fed a chow diet supplemented with 3 g LA per kg diet or pair fed for two weeks. At the end of the trial, high-quality RNA was extracted from the liver and epididymal fat and subjected to transcriptome analysis using RNA-Seq technology. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL10287
16 Samples
Download data: TSV, TXT
Series
Accession:
GSE50424
ID:
200050424
9.

Sex-different hepatic glycogen content, glucose and amino acid output in rats.

(Submitter supplied) In the present study we tested the hypothesis that male and female rat livers respond differently to a change in nutrient availability or to insulin treatment. We compared hepatic gene expression, hepatic glycogen and glucose output, insulin sensitivity and amino acids, using healthy rats. Keywords: Hepatic gene expression, sex-differences
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL6528
4 Samples
Download data: GPR
Series
Accession:
GSE20601
ID:
200020601
10.

Uncovering the hepatic gene expression variations and sex-differences as response to high-fat diet consumption in the highly genetically diversity of the Collaborative Cross mouse model

(Submitter supplied) Hepatic gene expression variations and sex-differences due to high-fat diet consumption using the Collaborative Cross mouse model
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
84 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE126490
ID:
200126490
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