Similar studies for GEO DataSets (Select 200051314) - GEO DataSets - NCBI

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Items: 20

Select item 2000513141.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to benz(a)anthracene in lung, liver, and forestomach tissues

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
58 Samples

Download data: TXT

Series

Accession:: GSE51314

ID:: 200051314

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000513212.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to 7 individual PAHs in the lung, liver, and forestomach tissues

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
371 Samples

Download data: TXT

Series

Accession:: GSE51321

ID:: 200051321

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000513203.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to indeno(123,cd)pyrene in lung, liver, and forestomach tissues [IP]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
58 Samples

Download data: TXT

Series

Accession:: GSE51320

ID:: 200051320

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000513194.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to dibenz(ah)anthracene in lung and forestomach tissues [DBahA]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
38 Samples

Download data: TXT

Series

Accession:: GSE51319

ID:: 200051319

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000513185.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to chrysene in lung, liver, and forestomach tissues [Chr]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
56 Samples

Download data: TXT

Series

Accession:: GSE51318

ID:: 200051318

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000513176.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to benzo(k)fluoranthene in lung, liver, and forestomach tissues [BkF]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
42 Samples

Download data: TXT

Series

Accession:: GSE51317

ID:: 200051317

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000513167.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to benzo(ghi)perylene in lung, liver, and forestomach tissues [BghiP]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
60 Samples

Download data: TXT

Series

Accession:: GSE51316

ID:: 200051316

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000513158.

Sub-chronic transcriptional response in adult male MutaTMMouse following oral exposure to benzo(b)fluoranthene in lung, liver, and forestomach tissues [BbF]

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
59 Samples

Download data: TXT

Series

Accession:: GSE51315

ID:: 200051315

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001284719.

Benzo[a]pyrene and dibenzo[def,p]chrysene in 3D primary human bronchial epithelial cells [RNA-seq]

(Submitter supplied) In this study, we assess potential differences in mechanism of action for two PAHs, benzo[a]pyrene (BAP) and dibenzo-[def,p]chrysene (DBC), in a primary human 3D bronchial epithelial culture (HBEC) model based on short-term biosignatures identified from global transcriptional profiling.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21290
12 Samples

Download data: TXT

Series

Accession:: GSE128471

ID:: 200128471

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20008769110.

Sub-chronic pulmonary transcriptional response to mixtures of polycyclic aromatic hydrocarbons (PAHs)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
57 Samples

Download data: TXT

Series

Accession:: GSE87691

ID:: 200087691

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008769011.

Sub-chronic pulmonary transcriptional response to coal tar, a PAH-containing complex mixture, in adult male MutaTMMouse.

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
20 Samples

Download data: TXT

Series

Accession:: GSE87690

ID:: 200087690

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008768912.

Sub-chronic pulmonary transcriptional response to a mixture of 8 polycyclic aromatic hydrocarbons in adult male MutaTMMouse.

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
19 Samples

Download data: TXT

Series

Accession:: GSE87689

ID:: 200087689

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008768813.

Sub-chronic pulmonary transcriptional response to a mixture of 4 PAHs in adult male MutaTMMouse.

(Submitter supplied) Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
18 Samples

Download data: TXT

Series

Accession:: GSE87688

ID:: 200087688

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004343814.

Sub-chronic forestomach transcriptional response in adult male MutaTMMouse following oral exposure to benzo(a)pyrene

(Submitter supplied) Benzo(a)pyrene is a well-established human carcinogen in humans and rodents. In the present study, we sought to determine the dose- and time-dependent changes in gene expression upon oral exposure to benzo(a)pyrene. Adult male MutaTMMouse were exposed to three doses of benzo(a)pyrene or vehicle control (olive oil) for 28 days and sacrificed three days after the final exposure.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
17 Samples

Download data: TXT

Series

Accession:: GSE43438

ID:: 200043438

PubMed Similar studies Analyze with GEO2R

Select item 20003945515.

Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

(Submitter supplied) The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of three environmental PAH mixtures (coal tar, diesel particulate and cigarette smoke condensate) using a two stage, FVB/N mouse skin tumor model. DBC (4 nmol) was most potent, reaching 100% tumor incidence with a shorter latency to tumor formation, less than 20 weeks of 12-O-tetradecanoylphorbol-13-acetate (TPA) promotion compared to all other treatments. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10787
25 Samples

Download data: TXT

Series

Accession:: GSE39455

ID:: 200039455

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002491016.

Lack of hepatic response of microRNA in mice following chronic benzo(a)pyrene exposure

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL4134 GPL8824
38 Samples

Download data: TXT

Series

Accession:: GSE24910

ID:: 200024910

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002490917.

Lack of hepatic response of microRNA in mice following chronic benzo(a)pyrene exposure (miRNA)

(Submitter supplied) Benzo[a]pyrene (BaP) is a very extensively studied prototypical polycyclic aromatic hydrocarbons (PAHs). Previous work in our laboratory showed no changes of microRNA (miRNA) expression in liver following a 3 days exposure to BaP, suggesting a lack of miRNA transcriptional responses to aryl hydrocarbon receptor agonists and/or DNA damage. Here, we studied 25-week old male MutaTM Mouse exposed to 25, 50, and 75 mg/kg/day BaP by oral gavage for 28 consecutive days. more...

Organism:: Mus musculus

Type:: Non-coding RNA profiling by array

Platform:: GPL8824
18 Samples

Download data: TXT

Series

Accession:: GSE24909

ID:: 200024909

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002490718.

Lack of hepatic response of microRNA in mice following chronic benzo(a)pyrene exposure (gene expression)

(Submitter supplied) Benzo[a]pyrene (BaP) is a very extensively studied prototypical polycyclic aromatic hydrocarbons (PAHs). Previous work in our laboratory showed no changes of microRNA (miRNA) expression in liver following a 3 days exposure to BaP, suggesting a lack of miRNA transcriptional responses to aryl hydrocarbon receptor agonists and/or DNA damage. Here, we studied 25-week old male MutaTM Mouse exposed to 25, 50, and 75 mg/kg/day BaP by oral gavage for 28 consecutive days. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL4134
20 Samples

Download data: TXT

Series

Accession:: GSE24907

ID:: 200024907

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20003571819.

Pulmonary gene expression in MutaTMMouse orally gavaged with three doses of benzo(a)pyrene and vehicle control

(Submitter supplied) In this study, we investigate mRNA profiles in lung of mice exposed to benzo(a)pyrene. Male mice were exposed to three doses (25, 50, and 75 mg/kg/day BaP) for 28 days and profiles were examined three days post-exposure. Our analyses reveal that BaP causes pulmonary specific cellular transformation indicative of carcinogenesis.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL4134
19 Samples

Download data: TXT

Series

Accession:: GSE35718

ID:: 200035718

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20015614720.

Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures

(Submitter supplied) In this study, we compare genomic signature safter treatment ofprimary human bronchial epithelial cells (HBEC) cultured in 3D with polycyclic aromatic hydrocarbons (PAHs) and identify genesets predictive of cancer risk.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21290
29 Samples

Download data: TXT

Series

Accession:: GSE156147

ID:: 200156147

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

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