Similar studies for GEO DataSets (Select 200072198) - GEO DataSets

Links from GEO DataSets

Items: 20

Select item 2000721981.

Differentially Expressed microRNAs in Bone Marrow Mesenchymal Stem Cell-derived Microvesicles in Young and Older Rats and Their Effect on Tumor Growth Factor-β1-mediated Epithelial-Mesenchymal Transition in HK2 cells

(Submitter supplied) miRNA profiles of the Young-MSC-MVs and Old-MSC-MVs were analyzed with a quantitative PCR (qPCR)-based array of the whole rat genome. Further analysis revealed the expression of miR-344a, miR-133b-3p, miR-294, miR-423-3p, and miR-872-3p was significantly downregulated in Old-MSC-MVs than in Young-MSC-MVs (p<0.05).

Organism:: Rattus norvegicus; Human alphaherpesvirus 2; JC polyomavirus; Betapolyomavirus hominis; Homo sapiens; Rhadinovirus; Merkel cell polyomavirus; Human alphaherpesvirus 1; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae; Human immunodeficiency virus 1

Type:: Non-coding RNA profiling by array

Platform:: GPL19128
6 Samples

Download data: GPR, TXT

Series

Accession:: GSE72198

ID:: 200072198

PubMed Full text in PMC Similar studies

Select item 2000686652.

Influence of Erythropoietin on Microvesicles Derived from Mesenchymal Ste cells(MSC) protecting renal function of Chronic Kidney Disease

(Submitter supplied) miRNA profiles of the MSC-MVs and EPO-MVs were analyzed with a quantitative PCR (qPCR)-based array of the whole mice genome. Further analysis revealed differences in the miRNAs of 212 EPO-MVs (fold change ≥ 1.5 compared to the MSC-MVs), which constituted approximately 22.64% of all of the evaluated mouse miRNAs. Of all of the differences, 70.28% of the changes in the EPO-MV group involved upregulation

Organism:: Mus musculus

Type:: Non-coding RNA profiling by array

Platform:: GPL20167
2 Samples

Download data: GPR

Series

Accession:: GSE68665

ID:: 200068665

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000861863.

miRNA expression data before and after TGF-β treatment and Ago2-associated transcripts in lung fibroblasts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: synthetic construct; Homo sapiens

Type:: Other; Non-coding RNA profiling by array

Platforms:: GPL21185 GPL8786
34 Samples

Download data: CEL

Series

Accession:: GSE86186

ID:: 200086186

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000861854.

miRNA expression data in unstimulated and TGF-β1-stimulated lung fibroblasts

(Submitter supplied) Lung fibroblasts play an important role in extracellular matrix homeostasis and this process is mainly regulated by transforming growth factor-beta (TGF-β). Hence, lung fibroblasts are postulated to play a crucial role in aberrant lung tissue repair and remodeling, which is a main factor in lung diseases like COPD. In this study, the effect of TGF-β1 on the miRNA expression in parenchymal lung fibroblasts is investigated.

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL8786
18 Samples

Download data: CEL

Series

Accession:: GSE86185

ID:: 200086185

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000861835.

mRNA expression profiling after Ago2-immunoprecipitation (IP) in unstimulated and TGF-β1-stimulated primary parenchymal lung fibroblasts of two control subjects

(Submitter supplied) To identify the target gene repertoire of miRNAs (i.e. the miRNA-targetome) of unstimulated and TGF-β1-stimulated primary parenchymal lung fibroblasts, Ago2-IP was performed followed by mRNA expression profiling.

Organism:: Homo sapiens

Type:: Other

Platform:: GPL21185
16 Samples

Download data: TXT

Series

Accession:: GSE86183

ID:: 200086183

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001481446.

Differentially expressed miRNAs in mice renal tubular epithelial cells which co-cultured with mesenchymal stem cells vs controls

(Submitter supplied) In order to study the effect of mesenchymal stem cells on miRNAs in renal tubular epithelial cells during renal fibrosis, and to find new treatment methods for renal fibrosis, we used TGF-β1 to stimulate mouse tubular epithelial cells, co-cultured with mesenchymal stem cells for 48 hours, and collected renal tubular epithelial cells .The renal tubular epithelial cells that were only stimulated by TGF-β1 were used as a control group. more...

Organism:: Mus musculus

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL13112
6 Samples

Download data: XLSX

Series

Accession:: GSE148144

ID:: 200148144

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000990827.

MicroRNA expression profiling of extracellular vesicles derived from human BM-MSC

(Submitter supplied) Human MSC are tissue stem cells that show multiple biological effects. At the present, how BM-MSC exert their effects are not fully understood. In this study, a novel cell-cell communication mediator, extraxellular vesicles (EV), were examined in the involvement of BM-MSC-mediated biological effects.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL21263
2 Samples

Download data: TXT

Series

Accession:: GSE99082

ID:: 200099082

Select item 2001832278.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
30 Samples

Download data: CEL

Series

Accession:: GSE183227

ID:: 200183227

Select item 2001832269.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients Before Transplantation and Unpaired Bone Marrow Donors

(Submitter supplied) Fanconi anemia (FA) is a rare genetic disorder characterized by genomic instability, developmental defects and bone marrow failure. Homeostasis of hematopoietic stem cells (HSCs) in the bone marrow partly relies on their direct or indirect interactions with the mesenchymal stem/stromal cells (MSCs). miRNAs can play a critical role during these interactions. There is no study available so far addressing the miRNA profile of bone marrow (BM-) MSCs in the FA disease state. more...

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
9 Samples

Download data: CEL

Series

Accession:: GSE183226

ID:: 200183226

Select item 20018322510.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients Before and After Bone Marrow Transplantation, and their Allogeneic Bone Marrow Donors

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
9 Samples

Download data: CEL

Series

Accession:: GSE183225

ID:: 200183225

Select item 20018322411.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients Before Transplantation and their Allogeneic Bone Marrow Donors

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
12 Samples

Download data: CEL

Series

Accession:: GSE183224

ID:: 200183224

Select item 20007085612.

Real-time quantitative PCR analysis for validation of miRNAs expressed during osteogenic differentiation of bone marrow MSCs versus healthy donors MSCs

(Submitter supplied) Total small RNA was isolated from BM-MSCs obtained from OA diagnosed patients (n=10) and non-OA (n=10 after osteogenic induction for 1, 10 and 21 days. miRNAs, were initially screened and those with consistent differential expression were selected for further validation by qRT-PCR analysis.

Organism:: Homo sapiens

Type:: Expression profiling by RT-PCR

Platform:: GPL20685
24 Samples

Download data: TXT

Series

Accession:: GSE70856

ID:: 200070856

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20014029713.

IGF-1-mediated microRNA profile in glioblastoma

(Submitter supplied) Insulin-like growth factor (IGF)-1 signaling and micro (mi)RNAs are relevant in mediating GBM progression. However, their roles in desensitizing GBM cells to TMZ are still unclear. We aimed to identify IGF-1-mediated miRNA regulatory networks that elicit TMZ insensitivity for GBM. By miRNA array analyses, totally 1,308 miRNAs were examined. The 93 upregulated and 148 downregulated miRNAs were identified in IGF-1-treated glioma cells.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL18310
4 Samples

Download data: GPR

Series

Accession:: GSE140297

ID:: 200140297

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010462914.

MiRNA expression profiling in cholangiocarcinoma (CCA) cells treated with TGF-b

(Submitter supplied) Expression profiling of 2555 miRNAs was performed using microarray. Of these, 451 miRNAs expressed in CCA cells. Microarray identified 17 miRNAs that were increased by > 1.5-fold and 56 miRNAs that were decreased by < 0.67-fold in CCA cells treated with TGF-β.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL18941
6 Samples

Download data: TXT

Series

Accession:: GSE104629

ID:: 200104629

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20017881015.

Detection Novel miRNA Potentially Involved in Proximal Tubules under Hypoxia Using Next-Generation Sequencing and Bioinformatic Approaches

(Submitter supplied) MicroRNAs are hypothesized to play critical roles in the regulation ofhypoxia-induced proximal tubular injury. The aim of this study is to explore novel microRNAs differentially expressed in HK-2 cells under normoxia and hypoxia conditions. RNAs were extracted from HK-2 cells cultured under normoxia and hypoxia for sequencing. Using the next generation sequencing and bioinformatics approaches, we identified 11 differentially expressed microRNAs in HK-2 cells under hypoxia condition.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL18573
2 Samples

Download data: XLSX

Series

Accession:: GSE178810

ID:: 200178810

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20006515316.

Deregulation of focal adhesion pathway mediated by miR-659-3p is implicated in bone marrow infiltration of stage M neuroblastoma patients

(Submitter supplied) Presence of BM-infiltrating neuroblastoma (NB) cells occurs in about 50% of patients affected by this peculiar pediatric cancer. Children aged more than 18 months at diagnosis with metastatic NB are high-risk patients with 25-30% overall survival at 5 years, despite multimodal aggressive therapy. Little is known about the metastatic process in NB patients. Hereby, we focused on miRNA expression profiles of BM-infiltrating as compared to those of primary NB tumors. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
8 Samples

Download data: TXT

Series

Accession:: GSE65153

ID:: 200065153

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007455917.

miRNA profile in the vitreous of proliferative vitreoretinal disease patients

(Submitter supplied) The microRNA profiles in the vitreous of proliferative vitreoretinal disease (PVD) such as proliferative diabetic retinopathy with fibrovascular membrane and macular hole (MH) patients were studied by RT-PCR.