Similar studies for GEO DataSets (Select 200091371) - GEO DataSets

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Items: 17

Select item 2000913711.

The CCAAT-Binding Complex Controls Mitochondrial Activity and Iron Homeostasis in Candida glabrata

(Submitter supplied) We conducted a network-based analysis of the Hap5 transcription factor belonging to the CCAAT-Binding Complex in Candida glabrata.

Organism:: Nakaseomyces glabratus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL22777
3 Samples

Download data: TXT

Series

Accession:: GSE91371

ID:: 200091371

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001299692.

The fungal CCAAT-binding complex and HapX display highly variable but evolutionary conserved synergetic promoter-specific DNA recognition

(Submitter supplied) To sustain iron homeostasis, microorganisms have evolved fine-tuned mechanisms for uptake, storage and detoxification of the essential metal iron. In the human pathogen Aspergillus fumigatus, the fungal-specific bZIP-type transcription factor HapX coordinates adaption to both iron starvation and iron excess and is thereby crucial for virulence. Previous studies indicated that a HapX homodimer interacts with the CCAAT-binding complex (CBC) to cooperatively bind bipartite DNA motifs; however, the significance of the HapX and CBC interaction and the mode of HapX-DNA recognition had not been resolved. more...

Organism:: Aspergillus fumigatus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL23268
12 Samples

Download data: BIGWIG

Series

Accession:: GSE129969

ID:: 200129969

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Select item 2000848163.

Candida glabrata WT and mutants under iron starvation

(Submitter supplied) Transcriptional time series of Candida glabrata under iron starvation (SD medium without Fe). Wild type and deletion mutants of the iron-related transcription factors Aft1 and Sef1, as well as of the iron uptake transporter Ftr1 as a positive control.

Organism:: Nakaseomyces glabratus; Nakaseomyces glabratus CBS 138

Type:: Expression profiling by array

Platform:: GPL10713
60 Samples

Download data: TXT

Series

Accession:: GSE84816

ID:: 200084816

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000978014.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Nakaseomyces glabratus; Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL22622 GPL13821
62 Samples

Download data: WIG

Series

Accession:: GSE97801

ID:: 200097801

PubMed Full text in PMC Similar studies

Select item 2000978005.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Cgla RNA-seq]

(Submitter supplied) In S. cerevisiae, the phosphate starvation (PHO) responsive transcription factors Pho4 and Pho2 are jointly required for induction of phosphate response genes and survival in phosphate starvation conditions. In the related human commensal and pathogen C. glabrata, Pho4 is required but Pho2 is dispensable for survival in phosphate-limited conditions and is only partially required for inducing the phosphate response genes. more...

Organism:: Nakaseomyces glabratus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL22622
8 Samples

Download data: CSV

Series

Accession:: GSE97800

ID:: 200097800

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Select item 2000977996.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Scer RNA-seq]

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13821
36 Samples

Download data: CSV

Series

Accession:: GSE97799

ID:: 200097799

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Select item 2000977987.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Cgla ChIP-seq]

Organism:: Nakaseomyces glabratus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL22622
9 Samples

Download data: WIG

Series

Accession:: GSE97798

ID:: 200097798

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000977978.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Scer ChIP-seq]

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13821
9 Samples

Download data: WIG

Series

Accession:: GSE97797

ID:: 200097797

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000412669.

Comparative analysis between wild type and hap5-null mutant in response to rapamycin treatment

(Submitter supplied) To identify the potential Hap5-regulated genes, we treated wild type cells and hap5 mutant cells with rapamycin and their corespondent transcriptional profiles were compared. Total 608 significant genes were identified. Among them, 343 genes are upregulated in hap5 mutant in repsonse to rapamycin while 265 genes are downregulated in comparison with the wild type.

Organism:: Candida albicans

Type:: Expression profiling by array

Platform:: GPL14575
8 Samples

Download data: TXT

Series

Accession:: GSE41266

ID:: 200041266

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007436110.

Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction With the Small Molecule iKIX1

(Submitter supplied) Eukaryotic transcription activators stimulate the expression of specific sets of target genes through recruitment of co-activators such as the RNA polymerase II-interacting Mediator complex. We previously identified an activator-targeted ~85 amino acid three-helix bundle KIX domain in the human MED15 Mediator subunit that is structurally conserved in Gal11 Mediator subunits in fungi. The Gal11 KIX domain is engaged by pleiotropic drug resistance transcription factor (Pdr1) orthologues, key regulators of the multidrug resistance (MDR) pathway in S. more...

Organism:: Nakaseomyces glabratus; Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL17342 GPL21066
24 Samples

Download data: TXT

Series

Accession:: GSE74361

ID:: 200074361

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Select item 20002842911.

Candida albicans Microarray studies: CAP2 (Wild type) vs. cap2D (Homozygous null mutant)

(Submitter supplied) Transcriptome profiling to identify Cap2/Hap43 regulons in the human fungal pathogen Candida albicans: Wild type vs. cap2D grown in iron-depleted medium

Organism:: Candida albicans

Type:: Expression profiling by array

Platform:: GPL4758
4 Samples

Download data: GPR

Series

Accession:: GSE28429

ID:: 200028429

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001024412.

Stress response in yeasts

(Submitter supplied) Transcriptome response of the yeasts C. glabrata and S. cerevisiae treated by an antifungal agent, benomyl Keywords: time course; stress response

Organism:: Nakaseomyces glabratus; Saccharomyces cerevisiae

Type:: Expression profiling by array

Platforms:: GPL6384 GPL6388
12 Samples

Download data: TXT

Series

Accession:: GSE10244

ID:: 200010244

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Select item 20006074113.

Response of Candida glabrata to environmental iron availability

(Submitter supplied) To examine the response of Candida glabrata cells to iron-depleted and iron-repleted environmental conditions, transcriptional profiling analysis was carried out on wild-type and Cghog1∆ cells grown either in presence of BPS or ferric chloride. Genes involved in iron transport and homeostasis, oxidative phosphorylation, amino acid metabolic process and chromatin silencing were found to be differentially regulated.

Organism:: Nakaseomyces glabratus CBS 138

Type:: Expression profiling by array

Platform:: GPL19118
12 Samples

Download data: TXT

Series

Accession:: GSE60741

ID:: 200060741

Select item 20007790414.

A network of paralogous stress response transcription factors in the human pathogen Candida glabrata

(Submitter supplied) We conducted a network-based analysis of the seven transcription factors belonging to the Yap (Yeast AP1) family in Candida glabrata.

Organism:: Nakaseomyces glabratus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL21453
22 Samples

Download data

Series

Accession:: GSE77904

ID:: 200077904

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Select item 20006868015.

ChIP-seq analysis of SREB during yeast phase growth of Blastomyces dermatitidis at 37oC

(Submitter supplied) ChIP-seq analysis was used to identify B. dermatitidis genes bound by the GATA transcription factor encoded by SREB during growth as yeast at 37oC

Organism:: Blastomyces dermatitidis ATCC 26199

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL20170
8 Samples

Download data: TXT

Series

Accession:: GSE68680

ID:: 200068680

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Select item 20011607716.

Comparative transcriptomics highlights new features of the iron starvation response in the human pathogen Candida glabrata

(Submitter supplied) We conducted a network-based analysis of the Aft2 transcription factor involved in iron starvation response in Candida glabrata.

Organism:: Nakaseomyces glabratus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL22777
3 Samples

Download data: TXT

Series

Accession:: GSE116077

ID:: 200116077

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20013936317.

Transcriptional analyses to decipher iron homeostasis in the pathogenic yeast Candida glabrata.

(Submitter supplied) Microarray experiments were performed to reveal the key genes involved in iron homeostasis in the pathogenic yeast Candida glabrata.