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Links from GEO DataSets

Items: 15

1.

Comparative transcriptomics highlights new features of the iron starvation response in the human pathogen Candida glabrata

(Submitter supplied) We conducted a network-based analysis of the Aft2 transcription factor involved in iron starvation response in Candida glabrata.
Organism:
Nakaseomyces glabratus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL22777
3 Samples
Download data: TXT
Series
Accession:
GSE116077
ID:
200116077
2.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Nakaseomyces glabratus; Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL22622 GPL13821
62 Samples
Download data: WIG
Series
Accession:
GSE97801
ID:
200097801
3.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Cgla RNA-seq]

(Submitter supplied) In S. cerevisiae, the phosphate starvation (PHO) responsive transcription factors Pho4 and Pho2 are jointly required for induction of phosphate response genes and survival in phosphate starvation conditions. In the related human commensal and pathogen C. glabrata, Pho4 is required but Pho2 is dispensable for survival in phosphate-limited conditions and is only partially required for inducing the phosphate response genes. more...
Organism:
Nakaseomyces glabratus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL22622
8 Samples
Download data: CSV
Series
Accession:
GSE97800
ID:
200097800
4.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Scer RNA-seq]

(Submitter supplied) In S. cerevisiae, the phosphate starvation (PHO) responsive transcription factors Pho4 and Pho2 are jointly required for induction of phosphate response genes and survival in phosphate starvation conditions. In the related human commensal and pathogen C. glabrata, Pho4 is required but Pho2 is dispensable for survival in phosphate-limited conditions and is only partially required for inducing the phosphate response genes. more...
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13821
36 Samples
Download data: CSV
Series
Accession:
GSE97799
ID:
200097799
5.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Cgla ChIP-seq]

(Submitter supplied) In S. cerevisiae, the phosphate starvation (PHO) responsive transcription factors Pho4 and Pho2 are jointly required for induction of phosphate response genes and survival in phosphate starvation conditions. In the related human commensal and pathogen C. glabrata, Pho4 is required but Pho2 is dispensable for survival in phosphate-limited conditions and is only partially required for inducing the phosphate response genes. more...
Organism:
Nakaseomyces glabratus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL22622
9 Samples
Download data: WIG
Series
Accession:
GSE97798
ID:
200097798
6.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Scer ChIP-seq]

(Submitter supplied) In S. cerevisiae, the phosphate starvation (PHO) responsive transcription factors Pho4 and Pho2 are jointly required for induction of phosphate response genes and survival in phosphate starvation conditions. In the related human commensal and pathogen C. glabrata, Pho4 is required but Pho2 is dispensable for survival in phosphate-limited conditions and is only partially required for inducing the phosphate response genes. more...
Organism:
Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13821
9 Samples
Download data: WIG
Series
Accession:
GSE97797
ID:
200097797
7.

A network of paralogous stress response transcription factors in the human pathogen Candida glabrata

(Submitter supplied) We conducted a network-based analysis of the seven transcription factors belonging to the Yap (Yeast AP1) family in Candida glabrata.
Organism:
Nakaseomyces glabratus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21453
22 Samples
Download data
Series
Accession:
GSE77904
ID:
200077904
8.

Candida glabrata WT and mutants under iron starvation

(Submitter supplied) Transcriptional time series of Candida glabrata under iron starvation (SD medium without Fe). Wild type and deletion mutants of the iron-related transcription factors Aft1 and Sef1, as well as of the iron uptake transporter Ftr1 as a positive control.
Organism:
Nakaseomyces glabratus; Nakaseomyces glabratus CBS 138
Type:
Expression profiling by array
Platform:
GPL10713
60 Samples
Download data: TXT
Series
Accession:
GSE84816
ID:
200084816
9.

Response of Candida glabrata to environmental iron availability

(Submitter supplied) To examine the response of Candida glabrata cells to iron-depleted and iron-repleted environmental conditions, transcriptional profiling analysis was carried out on wild-type and Cghog1∆ cells grown either in presence of BPS or ferric chloride. Genes involved in iron transport and homeostasis, oxidative phosphorylation, amino acid metabolic process and chromatin silencing were found to be differentially regulated.
Organism:
Nakaseomyces glabratus CBS 138
Type:
Expression profiling by array
Platform:
GPL19118
12 Samples
Download data: TXT
Series
Accession:
GSE60741
ID:
200060741
10.

Defining the transcriptome landscape of Candida glabrata during pH change and nitrosative stress by RNA-Seq

(Submitter supplied) The yeast Candida glabrata is one of the most important human fungal pathogens and has emerged as a leading cause of nosocomial bloodstream infections. Its resistance to many routinely used antimycotics and its close relationship to the model organism Saccharomyces cerevisiae make this fungus an interesting target of biomedical research. Although the genome sequence was published a decade ago, little is known about the transcriptional dynamics within this pathogen, especially compared to other pathogenic and nonpathogenic yeasts.We provide a detailed RNA-Seq-based analysis of the transcriptomic landscape of C. more...
Organism:
Nakaseomyces glabratus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19215
16 Samples
Download data: XLS
Series
Accession:
GSE61606
ID:
200061606
11.

The CCAAT-Binding Complex Controls Mitochondrial Activity and Iron Homeostasis in Candida glabrata

(Submitter supplied) We conducted a network-based analysis of the Hap5 transcription factor belonging to the CCAAT-Binding Complex in Candida glabrata.
Organism:
Nakaseomyces glabratus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL22777
3 Samples
Download data: TXT
Series
Accession:
GSE91371
ID:
200091371
12.

Transcriptional analyses to decipher iron homeostasis in the pathogenic yeast Candida glabrata.

(Submitter supplied) Microarray experiments were performed to reveal the key genes involved in iron homeostasis in the pathogenic yeast Candida glabrata.
Organism:
Nakaseomyces glabratus
Type:
Expression profiling by array
Platform:
GPL27653
17 Samples
Download data: GPR
Series
Accession:
GSE139363
ID:
200139363
13.

Unravelling adaptive mechanisms to H2O2 in Candida glabrata using laboratory adaptive evolution

(Submitter supplied) Transcriptome analysis of C. glabrata mutants evolved for improved tolerance to H2O2.
Organism:
Nakaseomyces glabratus
Type:
Expression profiling by array
Platform:
GPL23894
8 Samples
Download data: GPR
Series
Accession:
GSE102502
ID:
200102502
14.

Transcriptional effect of aft1 and aft2 mutation in iron depleted conditions

(Submitter supplied) The paralogous transcription factors Aft1p and Aft2p activate the expression of genes involved in iron metabolism under iron depleted conditions. Both are able to bind to the same DNA consensus sequence in vitro. We used DNA microarrays and loss of function mutant strains to better understand the respective roles of Aft1p and Aft2p in the regulation of gene expression Keywords: other
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Platform:
GPL205
6 Samples
Download data
Series
Accession:
GSE1763
ID:
200001763
15.

Transcriptional network controlled by Candida glabrata Ada2, a transcription coactivator

(Submitter supplied) In order to identify genes governed by Ada2, a transcription coactivator in C. glabrata, we compared the genome-wide expression profile in wild-type strain CBS138 and ada2 mutant via RNA sequencing. According to our analyses, 43 genes were down- and 443 genes were up-regulated in ada2 mutant when compared with the wild-type. The 43 down-regulated genes involved in ergosterol biosynthesis pathway (ERG6, ERG13), adhesin or adhesin-like genes (ICS2, AWP2, EPA7), heat shock genes (HSP30, SSB2) and other cellular functions. more...
Organism:
Nakaseomyces glabratus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19215
2 Samples
Download data: TXT
Series
Accession:
GSE76338
ID:
200076338
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