GEO DataSets

(Submitter supplied) Infections with bovine viral diarrhea virus (BVDV) contribute significantly to health-related economic losses in the beef and dairy industries and are widespread throughout the world. Severe acute BVDV infection is characterized by a gastrointestinal (GI) inflammatory response. The mechanism of inflammatory lesions caused by BVDV remains unknown. The interstitial cells of Cajal (ICC) network plays a pivotal role as a pacemaker in the generation of electrical slow waves for GI motility, and it is crucial for the reception of regulatory inputs from the enteric nervous system. more...

Organism:

Ovis aries

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19778

6 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling by array was performed to investigate differentially expressed genes (DEGs) in MDBK cells infected with field strains of BVDV and to further explore the molecular mechanism of underlying functional changes caused by infection.

Organism:

Bos taurus

Type:

Expression profiling by array

Platform:

GPL11649

16 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling by array was performed to investigate differentially expressed genes (DEGs) in BVDV-infected MDBK cells and to further explore the molecular mechanism of underlying functional changes caused by infection.

Organism:

Bos taurus

Type:

Expression profiling by array

Platform:

GPL11649

8 Samples

Download data: TXT

(Submitter supplied) The study investigated gene expression patterns in liver tissue to understand the biological functions of genes that are potentially involved in controlling / regulating feed efficiency in Nordic dairy cattle.

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19172

38 Samples

Download data: TXT

(Submitter supplied) Purpose: The goals of this study is to investigate host cell responses treated with lactobacillus in various molecular pathways by RNA-Seq and real-time quantitative PCR (RT-qPCR) methods to and evaluate protocols for optimal high-throughput data analysis. Methods: mRNA profiles of bovine vaginal epithelial cells treated with lactobacillus and control cells were generated by sequencing, in triplicate, utilizing Illumina HiSeq 4000 platform. more...

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23295

6 Samples

Download data: TXT

(Submitter supplied) To understand the mechanisms of sexual behaviour in rams, transcriptomic sequencing technology was used to identify differentially expressed genes in key brain tissues We then performed gene expression profiling analysis using data obtained from RNA-seq of hypothalamus (HT), pars tuberalis (PT) and pineal gland (PG) in rams with different sexual behaviours

Organism:

Ovis aries

Type:

Expression profiling by high throughput sequencing

Platform:

GPL27721

36 Samples

Download data: TXT

(Submitter supplied) We reported the bovine liver gene expression database of Polish-HF, Polish-Red and Hereford cattle breeds.

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24980

18 Samples

Download data: ZIP

(Submitter supplied) The adverse effects of sleep disorders on male fertility are increasingly concerning. In this study, a rat model of chronic sleep restriction (CSR) was established using the modified multiplatform method. The effects of CSR on the fertility of male rats were evaluated first based on sexual behavior. Serum hormones, including testosterone (T), prolactin (PRL), luteinizing hormone (LH) and follicle-stimulating hormone (FSH), and sperm parameters (concentration, viability, motility, deformation rate) were measured, and testicular histology was analysed by hematoxylin and eosin staining. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platforms:

GPL25029 GPL18469

18 Samples

Download data: TXT

(Submitter supplied) We performed RNA-seq analysis on the normal and 6-hour post-ONC retinas from the embryonic day (E) 20, postnatal day (P) 1 and P3 mice to determine the retinal transcriptome profiles. The identified differentially expressed genes (DEGs) could be associated with the degeneration of axonal growth capacity after birth, and axonal regeneration. Subsequent K‐means, GO, KEGG, PPI, and GSEA analysis revealed the biological processes and regulatory pathways involved in the DEGs.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24247

21 Samples

Download data: XLSX

(Submitter supplied) We conducted a genome-wide transcriptomic analysis in soybean leaves treated with a short-term (24 h) Pi-deficiency using RNA sequencing (RNA-seq) technology. Two biological replicates of RNA-seq were included for both Pi-sufficient leaves (PSL) and Pi-deficient leaves (PDL), and therefore a total of four libraries were constructed. Using a 2-fold change and a P-value ≤0.05 as the cut-off for selecting the differentially expressed transcripts, we globally identified short-term Pi-stress responsive genes. more...

Organism:

Glycine max

Type:

Expression profiling by high throughput sequencing

Platform:

GPL15008

4 Samples

Download data: XLSX

(Submitter supplied) we aimed to characterize the molecular functions and further investigate the regulatory network of degS in V. cholerae.

Organism:

Vibrio cholerae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL25044

4 Samples

Download data: XLS

(Submitter supplied) Differential expression profiling of light induction and primordium differentiation was established by integrating ATAC-seq (assay for transposase accessible chromatin with high through put sequencing) and RNA-seq technology. Key genes in light induced the primordium formation of S. latifolia were identified by bioinformatics methods.

Organism:

Sparassis latifolia

Type:

Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:

GPL26514 GPL26515

15 Samples

Download data: BED, TXT

(Submitter supplied) Purpose: to study the changes in various genes in cells during the early stages of SVA infection. Differentially expressed genes were screened from them, and GO enrichment analysis and KEGG pathway enrichment analysis were performed. This study provides some help for better prevention and control of SVA infection. Methods: Deep sequencing of SVA-infected cells at 6hpi and 12hpi and mock-infected cells were performed, in triplicate. more...

Organism:

Sus scrofa

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26351

12 Samples

Download data: TXT

(Submitter supplied) Purpose: To examine differential expression of genes in bovine macrophages under the influence of Toll-like receptor agonists. Goal: to study and understand the early phase of transcriptomic changes induced by Toll-like receptor in bovine macrophage cell line.

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23295

9 Samples

Download data: TXT

(Submitter supplied) Background: Weaning of beef calves is a necessary husbandry practice and involves separating the calf from its mother, resulting in numerous stressful events including dietary change, social reorganisation and the cessation of the maternal-offspring bond and is often accompanied by housing. While much recent research has focused on the physiological response of the bovine immune system to stress in recent years, little is known about the molecular mechanisms modulating the immune response. more...

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL11153

48 Samples

Download data: TXT

(Submitter supplied) Background: NK/T cell lymphoma (NKTCL) is a type of non-Hodgkin's lymphoma that occurs primarily extra nodal. The main treatment methods are radiotherapy and chemotherapy. The 5-year recurrence rate is still high, and there is currently no standard treatment for relapse-resistant patients. Compared with other lymphoid tumors, its malignancy is relatively strong, and the prognosis is not very good. Here, we try to identify the key genes and signaling pathways related to chemotherapy resistance in extra nodal NK/T cell lymphoma. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20301

12 Samples

Download data: XLS

(Submitter supplied) We use the Next generation sequencing (RNAseq) to profiling gene expression of CRFK cell.The purpose of this study are to comparison of CRFK gene expression between uninfected and infected by CPV isolated from Laos PDR

Organism:

Felis catus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17081

4 Samples

Download data: CSV

(Submitter supplied) In this study, we screened the differentially expressed genes (DEGs) in SH-SY5Y cells with Varicella-Zoster Virus-Infected using RNAseq technique to explore the molecular mechanisms of Herpes zoster pain

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23227

9 Samples

Download data: TXT

(Submitter supplied) Objectives: To analyze the gene expression profile of peripheral blood monocytes in different stages of coronary artery disease (CAD) by transcriptome sequencing, and to explore potential genes and pathway involved in CAD pathogenesis. Methods: According to the screening of coronary angiography and quality control of blood samples, 8 intermediate coronary lesion patients were selected, then 8 patients with acute myocardial infarction and 8 patients with normal coronary angiography were matched by age and gender. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20795

24 Samples

Download data: TXT

(Submitter supplied) We aimed to evaluate the transcriptome regulators associated with muscle growth and development between the Qianhua Mutton Merino (QHMM) and Small Tail Han (STH) sheep.We used RNA-Seq to obtain the transcriptome profiles of the longissimus muscle from the QHMM and STH.The genome-wide transcriptome analysis of QHMM and STH muscle in present study is reported first time.

Organism:

Ovis aries

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18884

6 Samples

Download data: TXT