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Links from GEO DataSets

Items: 20

1.

N57.Dataset

(Submitter supplied) Cytosine methylation data generated on mammalian methylation platform
Organism:
Rattus norvegicus; Balaena mysticetus; Homo sapiens; Mus musculus
Type:
Methylation profiling by array
Platform:
GPL28271
105 Samples
Download data: CSV, IDAT
Series
Accession:
GSE225288
ID:
200225288
2.

N14.Dataset

(Submitter supplied) Cytosine methylation data generated on mammalian methylation platform
Organism:
Homo sapiens; Mus musculus; Rattus norvegicus; Orcinus orca
Type:
Methylation profiling by array
Platform:
GPL28271
140 Samples
Download data: CSV, IDAT
Series
Accession:
GSE225289
ID:
200225289
3.

Genome Methylation in Wild Beluga Whales

(Submitter supplied) An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from skin samples of beluga whales, Maui's dolphin, and humpback whale. Tissue: Skin
Organism:
Homo sapiens; Physeter catodon; Delphinapterus leucas; Mus musculus; Rattus norvegicus; Cephalorhynchus hectori maui; Balaenoptera musculus; Megaptera novaeangliae
Type:
Methylation profiling by genome tiling array
Platform:
GPL28271
143 Samples
Download data: IDAT
Series
Accession:
GSE164465
ID:
200164465
4.

Methylation studies in roe deer

(Submitter supplied) An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from blood samples of roe deer n=94 blood samples
Organism:
Rattus norvegicus; Homo sapiens; Mus musculus; Capreolus capreolus
Type:
Methylation profiling by array
Platform:
GPL28271
94 Samples
Download data: CSV, DOCX, IDAT
Series
Accession:
GSE184216
ID:
200184216
5.

Methylation clocks for age estimation in toothed whales and dolphins

(Submitter supplied) An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from several tissues (skin, blood) in toothed whales and dolphins. Tissues: skin and blood.
Organism:
Delphinapterus leucas; Mus musculus; Rattus norvegicus; Lagenorhynchus obliquidens; Homo sapiens; Phocoena phocoena; Orcinus orca; Tursiops truncatus; Globicephala macrorhynchus; Steno bredanensis; Delphinus delphis; Cephalorhynchus commersonii
Type:
Methylation profiling by genome tiling array
Platform:
GPL28271
545 Samples
Download data: IDAT, TXT
Series
Accession:
GSE173330
ID:
200173330
6.

DNA methylation clocks as a predictor for ageing and age estimation in naked mole-rats, Heterocephalus glaber

(Submitter supplied) The naked mole-rat, Heterocephalus glaber (NMR), the longest-lived rodent with a maximum possible lifespan exceeding 33 years, is emerging as an important non-model organism for the study of longevity and healthspan. As such it is of significance and interest in the study of biomarkers for ageing in mammals. Recent breakthroughs in this field have indicated that ‘epigenetic clocks’ based on the temporal accumulation of DNA methylation at specific genomic sites can enable accurate age estimates for tissues across the lifespan of an individual. more...
Organism:
Heterocephalus glaber
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL27526
39 Samples
Download data: CSV
Series
Accession:
GSE137957
ID:
200137957
7.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species [Macaque_450k]

(Submitter supplied) We used blood samples from Macaque to determine rate of change of methylation with respect to age.
Organism:
Homo sapiens; Macaca mulatta
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
6 Samples
Download data
Series
Accession:
GSE104217
ID:
200104217
8.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species [TC1_450k]

(Submitter supplied) We used liver samples from TC1 Mice to determine rate of change of methylation with respect to age.
Organism:
Homo sapiens; Mus musculus
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
6 Samples
Download data: TXT
Series
Accession:
GSE104216
ID:
200104216
9.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species [Bis-PCR: naked mole-rat]

(Submitter supplied) We used liver samples from Naked Mole Rat to determine rate of change of methylation with respect to age.
Organism:
Heterocephalus glaber
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL24046
24 Samples
Download data: TXT
Series
Accession:
GSE104215
ID:
200104215
10.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Heterocephalus glaber; Homo sapiens; Canis lupus familiaris; Macaca mulatta
Type:
Methylation profiling by high throughput sequencing; Methylation profiling by genome tiling array
Platforms:
GPL24046 GPL13534 GPL22370
84 Samples
Download data: TXT
Series
Accession:
GSE86059
ID:
200086059
11.

The rate of ageing-associated DNA methylation dynamics is a molecular readout of lifespan variation amongst mammalian species [Bis-PCR: dog]

(Submitter supplied) We used buccal samples from two different dog breeds with well established differences in average lifespan to perform genome-scale identification of ageing-associated differentially methylated positions (aDMPs) in a total of 48 different dogs. A significant proportion of aDMPs that gained methylation with age replicated in an independent cohort. Furthermore, we also show that human aDMPs show similar ageing-associated dynamics at the homologous genomic regions in the dog. more...
Organism:
Canis lupus familiaris
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL22370
48 Samples
Download data: TXT
Series
Accession:
GSE86058
ID:
200086058
12.

Methylation studies in common marmoset

(Submitter supplied) DNA methylation data from common marmosets (Callithrix jacchus) profiled on the mammalian methylation array (HorvathMammalMethylChip40) which focuses on highly conserved CpGs across mammalian species. Rapamycin study in a subset of animals.
Organism:
Homo sapiens; Mus musculus; Callithrix jacchus; Rattus norvegicus
Type:
Methylation profiling by array
Platform:
GPL28271
96 Samples
Download data: CSV, DOCX, IDAT
Series
Accession:
GSE190663
ID:
200190663
13.

Methylation studies in rhesus macaque

(Submitter supplied) DNA methylation data from rhesus macaque (Macaca mulatta) profiled on the mammalian methylation array (HorvathMammalMethylChip40) which focuses on highly conserved CpGs across mammalian species. We profiled n = 283 tissue samples (blood, skin, adipose, kidney, liver, lung, muscle, and cerebral cortex)
Organism:
Mus musculus; Macaca mulatta; Homo sapiens; Rattus norvegicus
Type:
Methylation profiling by array
Platform:
GPL28271
283 Samples
Download data: CSV, DOCX, IDAT
Series
Accession:
GSE190664
ID:
200190664
14.

Methylation studies in the vervet monkey

(Submitter supplied) DNA methylation data from vervet cerebral cortex, blood, and liver using highly conserved mammalian CpGs represented on the mammalian methylation array (HorvathMammalMethylChip40). We selected a total of 240 samples representing the entire vervet lifespan, from neonatal to senile stages: 144 samples from the peripheral blood, 48 samples from the liver, and 48 samples from the cortical brain area BA10.
Organism:
Rattus norvegicus; Homo sapiens; Chlorocebus sabaeus; Mus musculus
Type:
Methylation profiling by array
Platform:
GPL28271
240 Samples
Download data: CSV, DOCX, IDAT
Series
Accession:
GSE190660
ID:
200190660
15.

The Australian Mammographic Density Twins and Sisters Study - DNA methylation data

(Submitter supplied) DNA methylation data for 479 women from 130 families including 66 monozygotic twin pairs, 66 dizygotic twin pairs and 215 sisters of twins.
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL13534
479 Samples
Download data: TXT
Series
Accession:
GSE100227
ID:
200100227
16.

Development of a novel aging clock based on chromatin accessibility

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
316 Samples
Download data
Series
Accession:
GSE193142
ID:
200193142
17.

Development of a novel aging clock based on chromatin accessibility [RNA-seq]

(Submitter supplied) The establishment of highly accurate aging clocks based on DNA methylation highlighted the strong link between epigenetic alterations and aging. However, connecting methylation clocks to physiological changes is not straightforward. Transcriptomics and proteomics clocks on the other hand are directly connected to cellular function, yet they do not allow us to understand underlying epigenetic mechanisms. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
159 Samples
Download data: CSV
Series
Accession:
GSE193141
ID:
200193141
18.

Development of a novel aging clock based on chromatin accessibility [ATAC-seq]

(Submitter supplied) The establishment of highly accurate aging clocks based on DNA methylation highlighted the strong link between epigenetic alterations and aging. However, connecting methylation clocks to physiological changes is not straightforward. Transcriptomics and proteomics clocks on the other hand are directly connected to cellular function, yet they do not allow us to understand underlying epigenetic mechanisms. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
157 Samples
Download data: TXT
Series
Accession:
GSE193140
ID:
200193140
19.

Genetic Loci and Metabolic States Associated With Murine Epigenetic Aging

(Submitter supplied) DNA methylation measured in mice belonging to the BXD Family using the HorvathMammalMethylChip40
Organism:
Mus musculus; Rattus norvegicus; Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL28271
339 Samples
Download data: IDAT
Series
Accession:
GSE199979
ID:
200199979
20.

Dysfunctional epigenetic aging of the normal colon and colorectal cancer risk

(Submitter supplied) Genome wide DNA methylation profiling of normal colon samples. The Illumina Infinium HumanMethylation450 and EPIC Beadchip arrays were used to obtain DNA methylation profiles across approximately 450,000 and 850,000 CpGs. Samples were from nomal colons of 334 subjects with low, medium or high CRC risk according to their personal adenoma or cancer history.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platforms:
GPL21145 GPL13534
334 Samples
Download data: IDAT
Series
Accession:
GSE132804
ID:
200132804
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