Similar studies for GEO DataSets (Select 200270164) - GEO DataSets

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Items: 14

Select item 2002701641.

De novo gene synthesis by an antiviral reverse transcriptase

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Escherichia coli str. K-12 substr. MG1655

Type:: Other; Expression profiling by high throughput sequencing

Platform:: GPL21117
75 Samples

Download data: BED, BW

Series

Accession:: GSE270164

ID:: 200270164

PubMed Similar studies

Select item 2002701622.

De novo gene synthesis by an antiviral reverse transcriptase [RNA-seq]

(Submitter supplied) Bacteria defend themselves from viral predation using diverse immune systems, many of which sense and target foreign nucleic acids. Defense-associated reverse transcriptase (DRT) systems provide an intriguing counterpoint to this immune strategy by instead leveraging DNA synthesis, but the identities and functions of their DNA products remain largely unknown. Here we show that DRT2 systems execute an unprecedented immunity mechanism that involves de novo gene synthesis via rolling-circle reverse transcription of a non-coding RNA (ncRNA). more...

Organism:: Escherichia coli str. K-12 substr. MG1655

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21117
3 Samples

Download data: BED

Series

Accession:: GSE270162

ID:: 200270162

PubMed Similar studies

Select item 2002701613.

De novo gene synthesis by an antiviral reverse transcriptase [RIP-seq]

Organism:: Escherichia coli str. K-12 substr. MG1655

Type:: Other

Platform:: GPL21117
36 Samples

Download data: BW

Series

Accession:: GSE270161

ID:: 200270161

PubMed Similar studies

Select item 2002701604.

De novo gene synthesis by an antiviral reverse transcriptase [cDIP-seq]

Organism:: Escherichia coli str. K-12 substr. MG1655

Type:: Other

Platform:: GPL21117
36 Samples

Download data: BW

Series

Accession:: GSE270160

ID:: 200270160

PubMed Similar studies

Select item 2001382005.

Template switching by a group II intron reverse transcriptase: biochemical analysis and implications for RNA-seq

(Submitter supplied) The reverse transcriptases (RTs) encoded by mobile group II intron and other non-LTR-retro-elements differ from retroviral RTs in being able to template switch from the 5' end of one template to the 3' end of another without pre-existing complementarity between the donor and acceptor nucleic acids. Here, we used the ability of a thermostable group II intron RT (TGIRT) to template switch directly from synthetic RNA template/DNA primer duplexes having either a blunt end or a 3'-DNA overhang end to establish a complete kinetic framework for the reaction and identify conditions that more efficiently capture acceptor RNAs or DNAs. more...

Organism:: synthetic construct

Type:: Other

Platform:: GPL19424
11 Samples

Download data: TSV

Series

Accession:: GSE138200

ID:: 200138200

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000209606.

Expression profiling data from mid-log phase cultures of wild type Vibrio campbellii BAA-1116

(Submitter supplied) Small RNA and regulatory RNA discovery has been based on (i) computational predictions mainly in intergenic regions, (ii) microarray experiments, (iii) shotgun cloning of cDNA libraries, (iv) classical cloning of abundant small RNAs after size fractionation in polyacrylamide gels and (v) copurification with proteins like Hfq, CsrA and RNA polymerase. In this study, we attempted to experimentally validate in silico small and regulatory RNA predictions for V. more...

Organism:: Vibrio campbellii CAIM 519 = NBRC 15631 = ATCC 25920

Type:: Expression profiling by array

Platform:: GPL10230
5 Samples

Download data: CEL

Series

Accession:: GSE20960

ID:: 200020960

Select item 2000623447.

Transcriptome Analysis of KSHV during de novo primary infection of human B-and endothelial-cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Human gammaherpesvirus 8

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17680
24 Samples

Download data: CSV

Series

Accession:: GSE62344

ID:: 200062344

PubMed Full text in PMC Similar studies

Select item 2000623438.

Transcriptome Analysis of KSHV virions produced from BCBL1 and BAC36 in 293L cells

(Submitter supplied) The objective of this study was to identify the viral transcripts packaged into the virion particles produced from BCBL1 cells as well as virions from 293L cells containing BAC36 BACs

Organism:: Human gammaherpesvirus 8

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17680
3 Samples

Download data: CSV

Series

Accession:: GSE62343

ID:: 200062343

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000623429.

Transcriptome Analysis of KSHV during de novo primary infection of endothelial (TIVE) cells

(Submitter supplied) The objective of this study was to identify the viral transcripts packaged into the virion particles and the transcription profiles of the viral genome during early infection, till the virus establishes latent infection in endothelial (TIVE) cells

Organism:: Human gammaherpesvirus 8

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17680
5 Samples

Download data: CSV

Series

Accession:: GSE62342

ID:: 200062342

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20006234110.

Transcriptome Analysis of KSHV during de novo primary infection of human B cells (PBMCs)

Organism:: Human gammaherpesvirus 8

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17680
5 Samples

Download data: CSV

Series

Accession:: GSE62341

ID:: 200062341

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20006234011.

Transcriptome Analysis of KSHV during de novo primary infection of human CD14+ cells

Organism:: Human gammaherpesvirus 8

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17680
5 Samples

Download data: CSV

Series

Accession:: GSE62340

ID:: 200062340

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20006233912.

Transcriptome Analysis of BAC36 and ORF59 deleted BAC36 during de novo primary infection of human B cells (PBMCs)

(Submitter supplied) The objective of this study was to identify the transcription profiles of wild type KSHV and ORF59 deleted KSHV (Kaposi's sarcoma-associated herpesvirus) genome during early infection, till the virus establishes latent infection in human PBMCs

Organism:: Human gammaherpesvirus 8

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17680
6 Samples

Download data: CSV

Series

Accession:: GSE62339

ID:: 200062339

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20010921013.

Transcriptional profiling of PNPase KO liver hepatocytes

(Submitter supplied) Transcriptional profiling of PNPase KO liver hepatocytes (HepKO) generated from Albumin-Cre/wt (liver-specific) Pnpt1 fl/fl C57BL/6J mice. Samples comparing liver hepatocyte PNPase KO (HepKO) cells to litter-, age-, and sex-matched wildtype hepatocyte control cells. The goal of this experiment was to determine effects of PNPase loss on the total RNA transcriptome under physiologic in vivo conditions.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL4134
4 Samples

Download data: TXT

Series

Accession:: GSE109210

ID:: 200109210

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20009495714.

Mitochondrial dsRNA triggers antiviral signalling in humans

(Submitter supplied) Mitochondria are descendants of endosymbiotic bacteria and retain essential prokaryotic features such as a compact circular genome. Consequently, in mammals, mitochondrial DNA is subjected to bidirectional transcription that generates overlapping transcripts capable of forming long double-stranded RNA structures. However, to our knowledge, mitochondrial double-stranded RNA has not been previously characterized in vivo. more...