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| Status |
Public on Dec 14, 2011 |
| Title |
Persistent Alterations in the imprinted miRNA and snoRNA populations in mouse models of fetal alcohol spectrum disorders (FASD) |
| Platform organism |
synthetic construct |
| Sample organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
We sought to characterize the persistnet changes in brain miRNAs across multiple mouse models of fetal alcohol exposure
We used miRNA expression arrays to characterize and observe the deregulation of brain specific ncRNAs
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| Overall design |
Whole brain tissue was harvested from day 70 fetal alcohol exposed males and matched controls for RNA extraction and hybridization to affymetrix miRNA 2.0 arrays. We obtained tissue from four models: Trimiester 1,2, and 3, injections and contious preference drinking.
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| Contributor(s) |
Laufer BI, Janus K, Kleiber ML, Diehl EJ, Singh SM |
| Citation(s) |
23580197 |
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| Submission date |
Dec 13, 2011 |
| Last update date |
May 02, 2017 |
| Contact name |
Benjamin I Laufer |
| Organization name |
Genentech
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| Street address |
1 DNA Way
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| City |
South San Francisco |
| State/province |
California |
| ZIP/Postal code |
94080 |
| Country |
USA |
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| Platforms (1) |
| GPL14613 |
[miRNA-2] Affymetrix Multispecies miRNA-2 Array |
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| Samples (18)
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| GSM848744 |
Day 70 CPD Ethanol, Biological Rep1 |
| GSM848745 |
Day 70 CPD Ethanol, Biological Rep2 |
| GSM848746 |
Day 70 CPD Ethanol, Biological Rep3 |
| GSM848747 |
Day 70 CPD Control, Biological Rep1 |
| GSM848748 |
Day 70 CPD Control, Biological Rep2 |
| GSM848749 |
Day 70 CPD Control, Biological Rep3 |
| GSM848750 |
Day 70 T3 Ethanol, Biological Rep1 |
| GSM848751 |
Day 70 T3 Ethanol, Biological Rep2 |
| GSM848752 |
Day 70 T3 Control, Biological Rep1 |
| GSM848753 |
Day 70 T3 Control, Biological Rep2 |
| GSM848754 |
Day 70 T2 Ethanol, Biological Rep1 |
| GSM848755 |
Day 70 T2 Ethanol, Biological Rep2 |
| GSM848756 |
Day 70 T2 Control, Biological Rep1 |
| GSM848757 |
Day 70 T2 Control, Biological Rep2 |
| GSM848758 |
Day 70 T1 Ethanol, Biological Rep1 |
| GSM848759 |
Day 70 T1 Ethanol, Biological Rep2 |
| GSM848760 |
Day 70 T1 Control, Biological Rep1 |
| GSM848761 |
Day 70 T1 Control, Biological Rep2 |
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| Relations |
| BioProject |
PRJNA149657 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE34413_RAW.tar |
13.5 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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