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Decreased sexual function

MedGen UID:
154293
•Concept ID:
C0549622
•
Mental or Behavioral Dysfunction
Synonyms: Abnormal sexual function; Impaired sexual function; Sexual disorder; Sexual dysfunction; Sexual Dysfunction
SNOMED CT: Sexual dysfunction (56925008); Impaired sexual function (225723003); Decreased sexual function (225723003); Sexual disorder (231532002); Abnormal sexual function (56925008)

Definition

Disturbances in sexual desire or performance. [from NCI]

Professional guidelines

PubMed

Health-related quality of life in women with primary ovarian insufficiency: a scoping review of the literature and implications for targeted interventions.
McDonald IR, Welt CK, Dwyer AA
Hum Reprod 2022 Nov 24;37(12):2817-2830. doi: 10.1093/humrep/deac200. PMID: 36102839Free PMC Article
Efficacy and satisfaction rates of oral PDE5is in the treatment of erectile dysfunction secondary to spinal cord injury: a review of literature.
Rizio N, Tran C, Sorenson M
J Spinal Cord Med 2012 Jul;35(4):219-28. doi: 10.1179/2045772312Y.0000000004. PMID: 22925748Free PMC Article
Menopause perspectives and treatment of Asian women.
Huang KE
Semin Reprod Med 2010 Sep;28(5):396-403. Epub 2010 Sep 15 doi: 10.1055/s-0030-1262899. PMID: 20845238

Recent clinical studies

Etiology

A systematic review and critical appraisal of menopause guidelines.
Hemachandra C, Taylor S, Islam RM, Fooladi E, Davis SR
BMJ Sex Reprod Health 2024 Apr 11;50(2):122-138. doi: 10.1136/bmjsrh-2023-202099. PMID: 38336466
Sexual function in primiparous women: a prospective study.
Dahlgren H, Jansson MH, Franzén K, Hiyoshi A, Nilsson K
Int Urogynecol J 2022 Jun;33(6):1567-1582. Epub 2022 Jan 1 doi: 10.1007/s00192-021-05029-w. PMID: 34973088Free PMC Article
Decreased sexual function in partners after patients' first-time myocardial infarction.
Arenhall E, Eriksson M, Nilsson U, Steinke EE, Fridlund B
Eur J Cardiovasc Nurs 2018 Aug;17(6):521-526. Epub 2018 Jan 2 doi: 10.1177/1474515117751904. PMID: 29291637
Association of sleep disturbance and sexual function in postmenopausal women.
Kling JM, Manson JE, Naughton MJ, Temkit M, Sullivan SD, Gower EW, Hale L, Weitlauf JC, Nowakowski S, Crandall CJ
Menopause 2017 Jun;24(6):604-612. doi: 10.1097/GME.0000000000000824. PMID: 28141665Free PMC Article
Cancer, Benign Gynecology, and Sexual Function--Issues and Answers.
Bennett N, Incrocci L, Baldwin D, Hackett G, El-Zawahry A, Graziottin A, Lukasiewicz M, McVary K, Sato Y, Krychman M
J Sex Med 2016 Apr;13(4):519-37. Epub 2016 Mar 25 doi: 10.1016/j.jsxm.2016.01.018. PMID: 27045256

Diagnosis

Impact of Gestational Diabetes Mellitus on Sexual Function: A Case-Control Study.
Nunes SK, Rudge CVC, Quiroz SCBV, Hallur RL, Prudencio CB, Pinheiro FA, Filho CIS, Odland J, Calderon IMP, Barbosa AMP, Rudge MVC
J Womens Health (Larchmt) 2020 Aug;29(8):1150-1159. Epub 2019 Oct 24 doi: 10.1089/jwh.2019.7794. PMID: 31647360
Development of a Sexual Dysfunction Scale for Women With Inflammatory Bowel Disease.
de Silva PS, O'Toole A, Marc LG, Ulysse CA, Testa MA, Julsgaard M, Ngyuen D, Ananthakrishnan A, Laursen T, Højgaard A, Christensen LA, Korzenik J, Friedman S
Inflamm Bowel Dis 2018 Oct 12;24(11):2350-2359. doi: 10.1093/ibd/izy202. PMID: 30165525Free PMC Article
Cancer, Benign Gynecology, and Sexual Function--Issues and Answers.
Bennett N, Incrocci L, Baldwin D, Hackett G, El-Zawahry A, Graziottin A, Lukasiewicz M, McVary K, Sato Y, Krychman M
J Sex Med 2016 Apr;13(4):519-37. Epub 2016 Mar 25 doi: 10.1016/j.jsxm.2016.01.018. PMID: 27045256
Sexual and relationship satisfaction and vestibular pain sensitivity among women with provoked vestibulodynia.
Smith KB, Pukall CF, Chamberlain SM
J Sex Med 2013 Aug;10(8):2009-23. Epub 2013 Jun 19 doi: 10.1111/jsm.12213. PMID: 23782506
Zinc and spinal cord injury: a review.
Sugarman B
J Am Paraplegia Soc 1984 Apr;7(2):39-42. doi: 10.1080/01952307.1984.11719602. PMID: 6374035

Therapy

Radical cystectomy and women's sexual health - can we do better?
Escott M, Avulova S, Bree KK, Westerman ME
Curr Opin Urol 2022 Sep 1;32(5):545-553. doi: 10.1097/MOU.0000000000001026. PMID: 35916011
Sexual function in primiparous women: a prospective study.
Dahlgren H, Jansson MH, Franzén K, Hiyoshi A, Nilsson K
Int Urogynecol J 2022 Jun;33(6):1567-1582. Epub 2022 Jan 1 doi: 10.1007/s00192-021-05029-w. PMID: 34973088Free PMC Article
Pharmacologically induced hypogonadism and sexual function in healthy young women and men.
Schmidt PJ, Steinberg EM, Negro PP, Haq N, Gibson C, Rubinow DR
Neuropsychopharmacology 2009 Feb;34(3):565-76. Epub 2008 Mar 19 doi: 10.1038/npp.2008.24. PMID: 18354393Free PMC Article
Complications of androgen-deprivation therapy for prostate cancer.
Holzbeierlein JM, Castle EP, Thrasher JB
Clin Prostate Cancer 2003 Dec;2(3):147-52. doi: 10.3816/cgc.2003.n.022. PMID: 15040857
Zinc and spinal cord injury: a review.
Sugarman B
J Am Paraplegia Soc 1984 Apr;7(2):39-42. doi: 10.1080/01952307.1984.11719602. PMID: 6374035

Prognosis

Development of a Sexual Dysfunction Scale for Women With Inflammatory Bowel Disease.
de Silva PS, O'Toole A, Marc LG, Ulysse CA, Testa MA, Julsgaard M, Ngyuen D, Ananthakrishnan A, Laursen T, Højgaard A, Christensen LA, Korzenik J, Friedman S
Inflamm Bowel Dis 2018 Oct 12;24(11):2350-2359. doi: 10.1093/ibd/izy202. PMID: 30165525Free PMC Article
Changes of sexual function and perception in Japanese men: A 15-year cross-sectional community-based study.
Takayanagi A, Kobayashi K, Fukuta F, Matsuki M, Matsuda Y, Mori M, Masumori N
Int J Urol 2016 Nov;23(11):941-945. Epub 2016 Aug 12 doi: 10.1111/iju.13184. PMID: 27520708
Cancer, Benign Gynecology, and Sexual Function--Issues and Answers.
Bennett N, Incrocci L, Baldwin D, Hackett G, El-Zawahry A, Graziottin A, Lukasiewicz M, McVary K, Sato Y, Krychman M
J Sex Med 2016 Apr;13(4):519-37. Epub 2016 Mar 25 doi: 10.1016/j.jsxm.2016.01.018. PMID: 27045256
Pharmacologically induced hypogonadism and sexual function in healthy young women and men.
Schmidt PJ, Steinberg EM, Negro PP, Haq N, Gibson C, Rubinow DR
Neuropsychopharmacology 2009 Feb;34(3):565-76. Epub 2008 Mar 19 doi: 10.1038/npp.2008.24. PMID: 18354393Free PMC Article
Urothelial carcinoma in the prostatic urethra and prostate: current controversies.
Liedberg F, Chebil G, Månsson W
Expert Rev Anticancer Ther 2007 Mar;7(3):383-90. doi: 10.1586/14737140.7.3.383. PMID: 17338657

Clinical prediction guides

Sexual function in primiparous women: a prospective study.
Dahlgren H, Jansson MH, Franzén K, Hiyoshi A, Nilsson K
Int Urogynecol J 2022 Jun;33(6):1567-1582. Epub 2022 Jan 1 doi: 10.1007/s00192-021-05029-w. PMID: 34973088Free PMC Article
Impact of Gestational Diabetes Mellitus on Sexual Function: A Case-Control Study.
Nunes SK, Rudge CVC, Quiroz SCBV, Hallur RL, Prudencio CB, Pinheiro FA, Filho CIS, Odland J, Calderon IMP, Barbosa AMP, Rudge MVC
J Womens Health (Larchmt) 2020 Aug;29(8):1150-1159. Epub 2019 Oct 24 doi: 10.1089/jwh.2019.7794. PMID: 31647360
Decreased sexual function in partners after patients' first-time myocardial infarction.
Arenhall E, Eriksson M, Nilsson U, Steinke EE, Fridlund B
Eur J Cardiovasc Nurs 2018 Aug;17(6):521-526. Epub 2018 Jan 2 doi: 10.1177/1474515117751904. PMID: 29291637
Association of sleep disturbance and sexual function in postmenopausal women.
Kling JM, Manson JE, Naughton MJ, Temkit M, Sullivan SD, Gower EW, Hale L, Weitlauf JC, Nowakowski S, Crandall CJ
Menopause 2017 Jun;24(6):604-612. doi: 10.1097/GME.0000000000000824. PMID: 28141665Free PMC Article
Pharmacologically induced hypogonadism and sexual function in healthy young women and men.
Schmidt PJ, Steinberg EM, Negro PP, Haq N, Gibson C, Rubinow DR
Neuropsychopharmacology 2009 Feb;34(3):565-76. Epub 2008 Mar 19 doi: 10.1038/npp.2008.24. PMID: 18354393Free PMC Article

Recent systematic reviews

A systematic review and critical appraisal of menopause guidelines.
Hemachandra C, Taylor S, Islam RM, Fooladi E, Davis SR
BMJ Sex Reprod Health 2024 Apr 11;50(2):122-138. doi: 10.1136/bmjsrh-2023-202099. PMID: 38336466
Health-related quality of life in women with primary ovarian insufficiency: a scoping review of the literature and implications for targeted interventions.
McDonald IR, Welt CK, Dwyer AA
Hum Reprod 2022 Nov 24;37(12):2817-2830. doi: 10.1093/humrep/deac200. PMID: 36102839Free PMC Article

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