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Refractory Malignant Head and Neck Neoplasm

MedGen UID:
1659739
Concept ID:
C4726631
Neoplastic Process
Synonym: Refractory Head and Neck Cancer

Definition

A malignant head and neck neoplasm that is resistant to treatment. [from NCI]

Professional guidelines

PubMed

Javle M, King G, Spencer K, Borad MJ
Oncologist 2023 Nov 2;28(11):928-943. doi: 10.1093/oncolo/oyad149. PMID: 37390492Free PMC Article
Capdevila J, Awada A, Führer-Sakel D, Leboulleux S, Pauwels P
Cancer Treat Rev 2022 May;106:102380. Epub 2022 Mar 15 doi: 10.1016/j.ctrv.2022.102380. PMID: 35305441
Schmidbauer B, Menhart K, Hellwig D, Grosse J
Int J Mol Sci 2017 Jun 17;18(6) doi: 10.3390/ijms18061292. PMID: 28629126Free PMC Article

Recent clinical studies

Etiology

Fallahi P, Ferrari SM, Galdiero MR, Varricchi G, Elia G, Ragusa F, Paparo SR, Benvenga S, Antonelli A
Semin Cancer Biol 2022 Feb;79:180-196. Epub 2020 Nov 26 doi: 10.1016/j.semcancer.2020.11.013. PMID: 33249201
Tuttle RM, Ahuja S, Avram AM, Bernet VJ, Bourguet P, Daniels GH, Dillehay G, Draganescu C, Flux G, Führer D, Giovanella L, Greenspan B, Luster M, Muylle K, Smit JWA, Van Nostrand D, Verburg FA, Hegedüs L
Thyroid 2019 Apr;29(4):461-470. doi: 10.1089/thy.2018.0597. PMID: 30900516
Ferris RL, Blumenschein G Jr, Fayette J, Guigay J, Colevas AD, Licitra L, Harrington K, Kasper S, Vokes EE, Even C, Worden F, Saba NF, Iglesias Docampo LC, Haddad R, Rordorf T, Kiyota N, Tahara M, Monga M, Lynch M, Geese WJ, Kopit J, Shaw JW, Gillison ML
N Engl J Med 2016 Nov 10;375(19):1856-1867. Epub 2016 Oct 8 doi: 10.1056/NEJMoa1602252. PMID: 27718784Free PMC Article
Schlumberger M, Tahara M, Wirth LJ, Robinson B, Brose MS, Elisei R, Habra MA, Newbold K, Shah MH, Hoff AO, Gianoukakis AG, Kiyota N, Taylor MH, Kim SB, Krzyzanowska MK, Dutcus CE, de las Heras B, Zhu J, Sherman SI
N Engl J Med 2015 Feb 12;372(7):621-30. doi: 10.1056/NEJMoa1406470. PMID: 25671254
Brose MS, Nutting CM, Jarzab B, Elisei R, Siena S, Bastholt L, de la Fouchardiere C, Pacini F, Paschke R, Shong YK, Sherman SI, Smit JW, Chung J, Kappeler C, Peña C, Molnár I, Schlumberger MJ; DECISION investigators
Lancet 2014 Jul 26;384(9940):319-28. Epub 2014 Apr 24 doi: 10.1016/S0140-6736(14)60421-9. PMID: 24768112Free PMC Article

Diagnosis

Leboulleux S, Do Cao C, Zerdoud S, Attard M, Bournaud C, Lacroix L, Benisvy D, Taïeb D, Bardet S, Terroir-Cassou-Mounat M, Anizan N, Bouvier-Morel E, Lamartina L, Lion G, Betrian S, Sajous C, Schiazza A, Garcia ME, Ciappuccini R, Schlumberger M, Al Ghuzlan A, Godbert Y, Borget I
Clin Cancer Res 2023 Jul 5;29(13):2401-2409. doi: 10.1158/1078-0432.CCR-23-0046. PMID: 37074727
Fallahi P, Ferrari SM, Galdiero MR, Varricchi G, Elia G, Ragusa F, Paparo SR, Benvenga S, Antonelli A
Semin Cancer Biol 2022 Feb;79:180-196. Epub 2020 Nov 26 doi: 10.1016/j.semcancer.2020.11.013. PMID: 33249201
Pei R, Shi Y, Lv S, Dai T, Zhang F, Liu S, Wu B
JAMA Netw Open 2021 May 3;4(5):e218065. doi: 10.1001/jamanetworkopen.2021.8065. PMID: 33956130Free PMC Article
Tuttle RM, Ahuja S, Avram AM, Bernet VJ, Bourguet P, Daniels GH, Dillehay G, Draganescu C, Flux G, Führer D, Giovanella L, Greenspan B, Luster M, Muylle K, Smit JWA, Van Nostrand D, Verburg FA, Hegedüs L
Thyroid 2019 Apr;29(4):461-470. doi: 10.1089/thy.2018.0597. PMID: 30900516
Schmidbauer B, Menhart K, Hellwig D, Grosse J
Int J Mol Sci 2017 Jun 17;18(6) doi: 10.3390/ijms18061292. PMID: 28629126Free PMC Article

Therapy

Zhang L, Feng Q, Wang J, Tan Z, Li Q, Ge M
Biochim Biophys Acta Rev Cancer 2023 Jul;1878(4):188928. Epub 2023 May 29 doi: 10.1016/j.bbcan.2023.188928. PMID: 37257629
Yilmaz E, Ismaila N, Bauman JE, Dabney R, Gan G, Jordan R, Kaufman M, Kirtane K, McBride SM, Old MO, Rooper L, Saba NF, Sheth S, Subramaniam RM, Wise-Draper TM, Wong D, Mell LK
J Clin Oncol 2023 Feb 10;41(5):1132-1146. Epub 2022 Dec 15 doi: 10.1200/JCO.22.02328. PMID: 36521102
Oh JM, Ahn BC
Theranostics 2021;11(13):6251-6277. Epub 2021 Apr 15 doi: 10.7150/thno.57689. PMID: 33995657Free PMC Article
Pei R, Shi Y, Lv S, Dai T, Zhang F, Liu S, Wu B
JAMA Netw Open 2021 May 3;4(5):e218065. doi: 10.1001/jamanetworkopen.2021.8065. PMID: 33956130Free PMC Article
Ferris RL, Blumenschein G Jr, Fayette J, Guigay J, Colevas AD, Licitra L, Harrington K, Kasper S, Vokes EE, Even C, Worden F, Saba NF, Iglesias Docampo LC, Haddad R, Rordorf T, Kiyota N, Tahara M, Monga M, Lynch M, Geese WJ, Kopit J, Shaw JW, Gillison ML
N Engl J Med 2016 Nov 10;375(19):1856-1867. Epub 2016 Oct 8 doi: 10.1056/NEJMoa1602252. PMID: 27718784Free PMC Article

Prognosis

Fallahi P, Ferrari SM, Galdiero MR, Varricchi G, Elia G, Ragusa F, Paparo SR, Benvenga S, Antonelli A
Semin Cancer Biol 2022 Feb;79:180-196. Epub 2020 Nov 26 doi: 10.1016/j.semcancer.2020.11.013. PMID: 33249201
Pu W, Shi X, Yu P, Zhang M, Liu Z, Tan L, Han P, Wang Y, Ji D, Gan H, Wei W, Lu Z, Qu N, Hu J, Hu X, Luo Z, Li H, Ji Q, Wang J, Zhang X, Wang YL
Nat Commun 2021 Oct 18;12(1):6058. doi: 10.1038/s41467-021-26343-3. PMID: 34663816Free PMC Article
Oh JM, Ahn BC
Theranostics 2021;11(13):6251-6277. Epub 2021 Apr 15 doi: 10.7150/thno.57689. PMID: 33995657Free PMC Article
Schmidbauer B, Menhart K, Hellwig D, Grosse J
Int J Mol Sci 2017 Jun 17;18(6) doi: 10.3390/ijms18061292. PMID: 28629126Free PMC Article
Ferris RL, Blumenschein G Jr, Fayette J, Guigay J, Colevas AD, Licitra L, Harrington K, Kasper S, Vokes EE, Even C, Worden F, Saba NF, Iglesias Docampo LC, Haddad R, Rordorf T, Kiyota N, Tahara M, Monga M, Lynch M, Geese WJ, Kopit J, Shaw JW, Gillison ML
N Engl J Med 2016 Nov 10;375(19):1856-1867. Epub 2016 Oct 8 doi: 10.1056/NEJMoa1602252. PMID: 27718784Free PMC Article

Clinical prediction guides

Leboulleux S, Do Cao C, Zerdoud S, Attard M, Bournaud C, Lacroix L, Benisvy D, Taïeb D, Bardet S, Terroir-Cassou-Mounat M, Anizan N, Bouvier-Morel E, Lamartina L, Lion G, Betrian S, Sajous C, Schiazza A, Garcia ME, Ciappuccini R, Schlumberger M, Al Ghuzlan A, Godbert Y, Borget I
Clin Cancer Res 2023 Jul 5;29(13):2401-2409. doi: 10.1158/1078-0432.CCR-23-0046. PMID: 37074727
Lee JS, Lee JS, Yun HJ, Kim SM, Chang H, Lee YS, Chang HS, Park CS
J Clin Endocrinol Metab 2023 May 17;108(6):1370-1375. doi: 10.1210/clinem/dgac739. PMID: 36546348Free PMC Article
Yilmaz E, Ismaila N, Bauman JE, Dabney R, Gan G, Jordan R, Kaufman M, Kirtane K, McBride SM, Old MO, Rooper L, Saba NF, Sheth S, Subramaniam RM, Wise-Draper TM, Wong D, Mell LK
J Clin Oncol 2023 Feb 10;41(5):1132-1146. Epub 2022 Dec 15 doi: 10.1200/JCO.22.02328. PMID: 36521102
Wang FH, Wei XL, Feng J, Li Q, Xu N, Hu XC, Liao W, Jiang Y, Lin XY, Zhang QY, Yuan XL, Huang HX, Chen Y, Dai GH, Shi JH, Shen L, Yang SJ, Shu YQ, Liu YP, Wang W, Wu H, Feng H, Yao S, Xu RH
J Clin Oncol 2021 Mar 1;39(7):704-712. Epub 2021 Jan 25 doi: 10.1200/JCO.20.02712. PMID: 33492986Free PMC Article
Schlumberger M, Tahara M, Wirth LJ, Robinson B, Brose MS, Elisei R, Habra MA, Newbold K, Shah MH, Hoff AO, Gianoukakis AG, Kiyota N, Taylor MH, Kim SB, Krzyzanowska MK, Dutcus CE, de las Heras B, Zhu J, Sherman SI
N Engl J Med 2015 Feb 12;372(7):621-30. doi: 10.1056/NEJMoa1406470. PMID: 25671254

Recent systematic reviews

Serioli S, Agostini L, Pietrantoni A, Valeri F, Costanza F, Chiloiro S, Buffoli B, Piazza A, Poliani PL, Peris-Celda M, Iavarone F, Gaudino S, Gessi M, Schinzari G, Mattogno PP, Giampietro A, De Marinis L, Pontecorvi A, Fontanella MM, Lauretti L, Rindi G, Olivi A, Bianchi A, Doglietto F
Int J Mol Sci 2023 Oct 29;24(21) doi: 10.3390/ijms242115719. PMID: 37958702Free PMC Article
Häuser W, Welsch P, Radbruch L, Fisher E, Bell RF, Moore RA
Cochrane Database Syst Rev 2023 Jun 5;6(6):CD014915. doi: 10.1002/14651858.CD014915.pub2. PMID: 37283486Free PMC Article
Maciejewski A, Lacka K
Int J Mol Sci 2022 Nov 7;23(21) doi: 10.3390/ijms232113661. PMID: 36362448Free PMC Article
Feng G, Luo Y, Zhang Q, Zeng F, Xu J, Zhu J
Endocrine 2020 Apr;68(1):56-63. Epub 2020 Jan 18 doi: 10.1007/s12020-019-02167-6. PMID: 31955344
Schmidbauer B, Menhart K, Hellwig D, Grosse J
Int J Mol Sci 2017 Jun 17;18(6) doi: 10.3390/ijms18061292. PMID: 28629126Free PMC Article

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