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Locally Advanced Nasopharyngeal Squamous Cell Carcinoma

MedGen UID:
1712139
Concept ID:
C5238483
Neoplastic Process

Definition

Nasopharyngeal squamous cell carcinoma that has spread to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Nasopharyngeal Squamous Cell Carcinoma

Professional guidelines

PubMed

Juarez-Vignon Whaley JJ, Afkhami M, Onyshchenko M, Massarelli E, Sampath S, Amini A, Bell D, Villaflor VM
Curr Treat Options Oncol 2023 Sep;24(9):1138-1166. Epub 2023 Jun 15 doi: 10.1007/s11864-023-01101-3. PMID: 37318724Free PMC Article
Saba NF, Salama JK, Beitler JJ, Busse PM, Cooper JS, Jones CU, Koyfman S, Quon H, Ridge JA, Siddiqui F, Worden F, Yao M, Yom SS; Expert Panel on Radiation Oncology-Head and Neck Cancer
Head Neck 2016 Jul;38(7):979-86. Epub 2016 Apr 30 doi: 10.1002/hed.24423. PMID: 27131050
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Recent clinical studies

Etiology

Ma Y, Huang Y, Zhao Y, Zhao S, Xue J, Yang Y, Fang W, Guo Y, Han Y, Yang K, Li Y, Yang J, Fu Z, Chen G, Chen L, Zhou N, Zhou T, Zhang Y, Zhou H, Liu Q, Zhu Y, Zhu H, Xiao S, Zhang L, Zhao H
Lancet Oncol 2024 Jul;25(7):901-911. Epub 2024 May 29 doi: 10.1016/S1470-2045(24)00159-1. PMID: 38823410
Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Lacas B, Bourhis J, Overgaard J, Zhang Q, Grégoire V, Nankivell M, Zackrisson B, Szutkowski Z, Suwiński R, Poulsen M, O'Sullivan B, Corvò R, Laskar SG, Fallai C, Yamazaki H, Dobrowsky W, Cho KH, Beadle B, Langendijk JA, Viegas CMP, Hay J, Lotayef M, Parmar MKB, Aupérin A, van Herpen C, Maingon P, Trotti AM, Grau C, Pignon JP, Blanchard P; MARCH Collaborative Group
Lancet Oncol 2017 Sep;18(9):1221-1237. Epub 2017 Jul 27 doi: 10.1016/S1470-2045(17)30458-8. PMID: 28757375Free PMC Article
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243
Al-Sarraf M, LeBlanc M, Giri PG, Fu KK, Cooper J, Vuong T, Forastiere AA, Adams G, Sakr WA, Schuller DE, Ensley JF
J Clin Oncol 1998 Apr;16(4):1310-7. doi: 10.1200/JCO.1998.16.4.1310. PMID: 9552031

Diagnosis

Giannini L, Alliata A, Cristofaro V, Incandela F, Pompilio M, Ottini A, Cavalieri S, Nuzzolese I, Iacovelli NA, Franceschini M, Deganello A
Curr Oncol 2023 Jul 14;30(7):6708-6719. doi: 10.3390/curroncol30070492. PMID: 37504352Free PMC Article
Juarez-Vignon Whaley JJ, Afkhami M, Onyshchenko M, Massarelli E, Sampath S, Amini A, Bell D, Villaflor VM
Curr Treat Options Oncol 2023 Sep;24(9):1138-1166. Epub 2023 Jun 15 doi: 10.1007/s11864-023-01101-3. PMID: 37318724Free PMC Article
Fulcher CD, Haigentz M Jr, Ow TJ; Education Committee of the American Head and Neck Society (AHNS)
Head Neck 2018 Apr;40(4):676-686. Epub 2017 Nov 24 doi: 10.1002/hed.25025. PMID: 29171929Free PMC Article
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243
Agulnik M, Epstein JB
Oral Oncol 2008 Jul;44(7):617-27. Epub 2007 Dec 3 doi: 10.1016/j.oraloncology.2007.08.003. PMID: 18061518

Therapy

Ma Y, Huang Y, Zhao Y, Zhao S, Xue J, Yang Y, Fang W, Guo Y, Han Y, Yang K, Li Y, Yang J, Fu Z, Chen G, Chen L, Zhou N, Zhou T, Zhang Y, Zhou H, Liu Q, Zhu Y, Zhu H, Xiao S, Zhang L, Zhao H
Lancet Oncol 2024 Jul;25(7):901-911. Epub 2024 May 29 doi: 10.1016/S1470-2045(24)00159-1. PMID: 38823410
Lacas B, Bourhis J, Overgaard J, Zhang Q, Grégoire V, Nankivell M, Zackrisson B, Szutkowski Z, Suwiński R, Poulsen M, O'Sullivan B, Corvò R, Laskar SG, Fallai C, Yamazaki H, Dobrowsky W, Cho KH, Beadle B, Langendijk JA, Viegas CMP, Hay J, Lotayef M, Parmar MKB, Aupérin A, van Herpen C, Maingon P, Trotti AM, Grau C, Pignon JP, Blanchard P; MARCH Collaborative Group
Lancet Oncol 2017 Sep;18(9):1221-1237. Epub 2017 Jul 27 doi: 10.1016/S1470-2045(17)30458-8. PMID: 28757375Free PMC Article
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243
Al-Sarraf M, Reddy MS
Curr Treat Options Oncol 2002 Feb;3(1):21-32. doi: 10.1007/s11864-002-0038-8. PMID: 12057084
Al-Sarraf M, LeBlanc M, Giri PG, Fu KK, Cooper J, Vuong T, Forastiere AA, Adams G, Sakr WA, Schuller DE, Ensley JF
J Clin Oncol 1998 Apr;16(4):1310-7. doi: 10.1200/JCO.1998.16.4.1310. PMID: 9552031

Prognosis

Bakst RL, Glastonbury CM, Parvathaneni U, Katabi N, Hu KS, Yom SS
Int J Radiat Oncol Biol Phys 2019 Apr 1;103(5):1109-1124. Epub 2018 Dec 15 doi: 10.1016/j.ijrobp.2018.12.009. PMID: 30562546
Kamran SC, Riaz N, Lee N
Surg Oncol Clin N Am 2015 Jul;24(3):547-61. Epub 2015 Apr 11 doi: 10.1016/j.soc.2015.03.008. PMID: 25979399
Nwizu T, Adelstein DJ
Expert Rev Anticancer Ther 2014 Sep;14(9):1033-9. Epub 2014 Jul 6 doi: 10.1586/14737140.2014.924399. PMID: 24998393
Al-Sarraf M, Reddy MS
Curr Treat Options Oncol 2002 Feb;3(1):21-32. doi: 10.1007/s11864-002-0038-8. PMID: 12057084
Al-Sarraf M, LeBlanc M, Giri PG, Fu KK, Cooper J, Vuong T, Forastiere AA, Adams G, Sakr WA, Schuller DE, Ensley JF
J Clin Oncol 1998 Apr;16(4):1310-7. doi: 10.1200/JCO.1998.16.4.1310. PMID: 9552031

Clinical prediction guides

Ma Y, Huang Y, Zhao Y, Zhao S, Xue J, Yang Y, Fang W, Guo Y, Han Y, Yang K, Li Y, Yang J, Fu Z, Chen G, Chen L, Zhou N, Zhou T, Zhang Y, Zhou H, Liu Q, Zhu Y, Zhu H, Xiao S, Zhang L, Zhao H
Lancet Oncol 2024 Jul;25(7):901-911. Epub 2024 May 29 doi: 10.1016/S1470-2045(24)00159-1. PMID: 38823410
Wong KCW, Johnson D, Hui EP, Lam RCT, Ma BBY, Chan ATC
Cancer Treat Rev 2022 Apr;105:102361. Epub 2022 Feb 16 doi: 10.1016/j.ctrv.2022.102361. PMID: 35231870
Liu K, Chen N, Wei J, Ma L, Yang S, Zhang X
Oncol Rep 2020 May;43(5):1525-1535. Epub 2020 Mar 9 doi: 10.3892/or.2020.7536. PMID: 32323844Free PMC Article
Mazzola R, Ferrera G, Alongi F, Mannino M, Abbate B, Cucchiara T, Iacoviello G, Sciumè F, Di Paola G, Federico M, Blasi L, Lo Casto A, Lagalla R, Messana D
Radiol Med 2015 Aug;120(8):753-8. Epub 2015 Feb 7 doi: 10.1007/s11547-015-0512-6. PMID: 25663551
Sanabria A, Silver CE, Olsen KD, Medina JE, Hamoir M, Paleri V, Mondin V, Rinaldo A, Rodrigo JP, Suárez C, Boedeker CC, Hinni ML, Kowalski LP, Teymoortash A, Werner JA, Takes RP, Ferlito A
Eur Arch Otorhinolaryngol 2014 Dec;271(12):3111-9. Epub 2014 Feb 11 doi: 10.1007/s00405-014-2893-x. PMID: 24515917

Recent systematic reviews

Jacinto JK, Co J, Mejia MB, Regala EE
Br J Radiol 2017 Nov;90(1079):20170442. doi: 10.1259/bjr.20170442. PMID: 29053029Free PMC Article
Szturz P, Wouters K, Kiyota N, Tahara M, Prabhash K, Noronha V, Castro A, Licitra L, Adelstein D, Vermorken JB
Oncologist 2017 Sep;22(9):1056-1066. Epub 2017 May 22 doi: 10.1634/theoncologist.2017-0015. PMID: 28533474Free PMC Article

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