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Locally Advanced Head and Neck Carcinoma

MedGen UID:
1660505
Concept ID:
C4727839
Neoplastic Process

Definition

A head and neck carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

Nouman M, Haider G, Bukhari N, Yousuf A, Nouman R, Shaikh MR, Hussain S, Pavan B, Rahool R, Memon P, Zahoor S, Mehar K, Sami A
Asian Pac J Cancer Prev 2020 Mar 1;21(3):825-830. doi: 10.31557/APJCP.2020.21.3.825. PMID: 32212813Free PMC Article
Rambeau A, Gervais R, De Raucourt D, Babin E, Dugué AE, Florescu C, Blanchard D, Gery B
Eur Arch Otorhinolaryngol 2017 Jul;274(7):2883-2889. Epub 2017 Apr 5 doi: 10.1007/s00405-017-4550-7. PMID: 28382396
Antognoni P, Camesasca G, Bianchi C, Nicoletti G, Villa E
Tumori 1990 Jun 30;76(3):238-43. doi: 10.1177/030089169007600306. PMID: 2368167

Recent clinical studies

Etiology

Tanaka R, Ueki Y, Ohshima S, Omata J, Yokoyama Y, Takahashi T, Shodo R, Yamazaki K, Ohtaki K, Togashi T, Horii A
Int J Clin Oncol 2024 Aug;29(8):1133-1141. Epub 2024 May 10 doi: 10.1007/s10147-024-02545-9. PMID: 38727853
Sreejeev AT, Joseph D, Krishnan AS, Pasricha R, Gupta S, Ahuja R, Sharma N, Sikdar D, Raut S, Sasi A, Gupta M
Head Neck 2024 Jul;46(7):1547-1556. Epub 2024 Mar 4 doi: 10.1002/hed.27710. PMID: 38436506
Lorini L, Perri F, Vecchio S, Belgioia L, Vinches M, Brana I, Elad S, Bossi P
Support Care Cancer 2022 Oct;30(10):8455-8463. Epub 2022 May 31 doi: 10.1007/s00520-022-07128-w. PMID: 35639187Free PMC Article
Acevedo-Henao CM, Valette G, Miglierini P, Lefur E, Pradier O
Cancer Radiother 2012 Oct;16(7):601-3. Epub 2012 Oct 22 doi: 10.1016/j.canrad.2012.06.005. PMID: 23089070
Bourhis J, Sire C, Graff P, Grégoire V, Maingon P, Calais G, Gery B, Martin L, Alfonsi M, Desprez P, Pignon T, Bardet E, Rives M, Geoffrois L, Daly-Schveitzer N, Sen S, Tuchais C, Dupuis O, Guerif S, Lapeyre M, Favrel V, Hamoir M, Lusinchi A, Temam S, Pinna A, Tao YG, Blanchard P, Aupérin A
Lancet Oncol 2012 Feb;13(2):145-53. Epub 2012 Jan 18 doi: 10.1016/S1470-2045(11)70346-1. PMID: 22261362

Diagnosis

Rambeau A, Gervais R, De Raucourt D, Babin E, Dugué AE, Florescu C, Blanchard D, Gery B
Eur Arch Otorhinolaryngol 2017 Jul;274(7):2883-2889. Epub 2017 Apr 5 doi: 10.1007/s00405-017-4550-7. PMID: 28382396
Raju U, Riesterer O, Wang ZQ, Molkentine DP, Molkentine JM, Johnson FM, Glisson B, Milas L, Ang KK
Radiother Oncol 2012 Nov;105(2):241-9. Epub 2012 Sep 23 doi: 10.1016/j.radonc.2012.08.010. PMID: 23010482
Kankaanranta L, Seppälä T, Koivunoro H, Saarilahti K, Atula T, Collan J, Salli E, Kortesniemi M, Uusi-Simola J, Välimäki P, Mäkitie A, Seppänen M, Minn H, Revitzer H, Kouri M, Kotiluoto P, Seren T, Auterinen I, Savolainen S, Joensuu H
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):e67-75. Epub 2011 Feb 6 doi: 10.1016/j.ijrobp.2010.09.057. PMID: 21300462
Le Stanc E, Vilain D, Baglin AC, Tainturier C
Clin Nucl Med 2009 Jul;34(7):435-8. doi: 10.1097/RLU.0b013e3181a7d001. PMID: 19542949
Wong G, Stidley C, Dressler L, Castillo M, Crooks L, Bartow S
J Laryngol Otol 1996 Mar;110(3):243-8. doi: 10.1017/s0022215100133316. PMID: 8730360

Therapy

Tanaka R, Ueki Y, Ohshima S, Omata J, Yokoyama Y, Takahashi T, Shodo R, Yamazaki K, Ohtaki K, Togashi T, Horii A
Int J Clin Oncol 2024 Aug;29(8):1133-1141. Epub 2024 May 10 doi: 10.1007/s10147-024-02545-9. PMID: 38727853
Truong MT, Zhang Q, Rosenthal DI, List M, Axelrod R, Sherman E, Weber R, Nguyen-Tân PF, El-Naggar A, Konski A, Galvin J, Schwartz D, Trotti A, Silverman C, Singh A, Godette K, Bonner JA, Jones CU, Garden AS, Shenouda G, Matthiesen C, Le QT, Bruner D
Int J Radiat Oncol Biol Phys 2017 Mar 15;97(4):687-699. Epub 2016 Aug 12 doi: 10.1016/j.ijrobp.2016.08.003. PMID: 27727066Free PMC Article
Arias F, Asín G, Uzcanga MI, Maraví E, Quílez I, Chicata V, Eito C, Viudez A, Hernández I, Mañeru F, Domínguez MA
Clin Transl Oncol 2014 Jun;16(6):555-60. Epub 2013 Nov 8 doi: 10.1007/s12094-013-1118-x. PMID: 24203760
Bourhis J, Sire C, Graff P, Grégoire V, Maingon P, Calais G, Gery B, Martin L, Alfonsi M, Desprez P, Pignon T, Bardet E, Rives M, Geoffrois L, Daly-Schveitzer N, Sen S, Tuchais C, Dupuis O, Guerif S, Lapeyre M, Favrel V, Hamoir M, Lusinchi A, Temam S, Pinna A, Tao YG, Blanchard P, Aupérin A
Lancet Oncol 2012 Feb;13(2):145-53. Epub 2012 Jan 18 doi: 10.1016/S1470-2045(11)70346-1. PMID: 22261362
Franchin G, Vaccher E, Gobitti C, Minatel E, Politi D, Talamini R, Di Gennaro G, Savignano G, Trovò MG, Tirelli U, Barzan L
Oral Oncol 2005 May;41(5):526-33. Epub 2005 Apr 9 doi: 10.1016/j.oraloncology.2004.12.013. PMID: 15878759

Prognosis

Guberina M, Sak A, Pöttgen C, Tinhofer-Keilholz I, Budach V, Balermpas P, Von der Grün J, Rödel CM, Gkika E, Grosu AL, Abdollahi A, Debus J, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, De-Colle C, Welz S, Linge A, Lohaus F, Baretton G, Gauler T, Baumann M, Krause M, Schuler M, Bankfalvi A, Höing B, Lang S, Stuschke M
Pharmacogenomics J 2021 Feb;21(1):37-46. Epub 2020 Jun 16 doi: 10.1038/s41397-020-0174-1. PMID: 32546699Free PMC Article
Gupta P, Dhull AK, Kaushal V
J Cancer Res Ther 2020 Apr-Jun;16(3):478-484. doi: 10.4103/jcrt.JCRT_475_18. PMID: 32719254
Truong MT, Zhang Q, Rosenthal DI, List M, Axelrod R, Sherman E, Weber R, Nguyen-Tân PF, El-Naggar A, Konski A, Galvin J, Schwartz D, Trotti A, Silverman C, Singh A, Godette K, Bonner JA, Jones CU, Garden AS, Shenouda G, Matthiesen C, Le QT, Bruner D
Int J Radiat Oncol Biol Phys 2017 Mar 15;97(4):687-699. Epub 2016 Aug 12 doi: 10.1016/j.ijrobp.2016.08.003. PMID: 27727066Free PMC Article
Xiao C, Zhang Q, Nguyen-Tân PF, List M, Weber RS, Ang KK, Rosenthal D, Filion EJ, Kim H, Silverman C, Raben A, Galloway T, Fortin A, Gore E, Winquist E, Jones CU, Robinson W, Raben D, Le QT, Bruner D
Int J Radiat Oncol Biol Phys 2017 Mar 15;97(4):667-677. Epub 2016 Jul 25 doi: 10.1016/j.ijrobp.2016.07.020. PMID: 27727063Free PMC Article
Acevedo-Henao CM, Valette G, Miglierini P, Lefur E, Pradier O
Cancer Radiother 2012 Oct;16(7):601-3. Epub 2012 Oct 22 doi: 10.1016/j.canrad.2012.06.005. PMID: 23089070

Clinical prediction guides

Tanaka R, Ueki Y, Ohshima S, Omata J, Yokoyama Y, Takahashi T, Shodo R, Yamazaki K, Ohtaki K, Togashi T, Horii A
Int J Clin Oncol 2024 Aug;29(8):1133-1141. Epub 2024 May 10 doi: 10.1007/s10147-024-02545-9. PMID: 38727853
Guberina M, Sak A, Pöttgen C, Tinhofer-Keilholz I, Budach V, Balermpas P, Von der Grün J, Rödel CM, Gkika E, Grosu AL, Abdollahi A, Debus J, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, De-Colle C, Welz S, Linge A, Lohaus F, Baretton G, Gauler T, Baumann M, Krause M, Schuler M, Bankfalvi A, Höing B, Lang S, Stuschke M
Pharmacogenomics J 2021 Feb;21(1):37-46. Epub 2020 Jun 16 doi: 10.1038/s41397-020-0174-1. PMID: 32546699Free PMC Article
Truong MT, Zhang Q, Rosenthal DI, List M, Axelrod R, Sherman E, Weber R, Nguyen-Tân PF, El-Naggar A, Konski A, Galvin J, Schwartz D, Trotti A, Silverman C, Singh A, Godette K, Bonner JA, Jones CU, Garden AS, Shenouda G, Matthiesen C, Le QT, Bruner D
Int J Radiat Oncol Biol Phys 2017 Mar 15;97(4):687-699. Epub 2016 Aug 12 doi: 10.1016/j.ijrobp.2016.08.003. PMID: 27727066Free PMC Article
Xiao C, Zhang Q, Nguyen-Tân PF, List M, Weber RS, Ang KK, Rosenthal D, Filion EJ, Kim H, Silverman C, Raben A, Galloway T, Fortin A, Gore E, Winquist E, Jones CU, Robinson W, Raben D, Le QT, Bruner D
Int J Radiat Oncol Biol Phys 2017 Mar 15;97(4):667-677. Epub 2016 Jul 25 doi: 10.1016/j.ijrobp.2016.07.020. PMID: 27727063Free PMC Article
Acevedo-Henao CM, Valette G, Miglierini P, Lefur E, Pradier O
Cancer Radiother 2012 Oct;16(7):601-3. Epub 2012 Oct 22 doi: 10.1016/j.canrad.2012.06.005. PMID: 23089070

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