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Locally Advanced Head and Neck Squamous Cell Carcinoma

MedGen UID:
1701136
Concept ID:
C5206801
Neoplastic Process

Definition

A head and neck squamous cell carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

Cavalieri S, Platini F, Barretta F, Nuzzolese I, Ottini A, Bergamini C, Resteghini C, Colombo E, Iacovelli NA, Franceschini M, Calareso G, Di Pede P, De Feo G, Gandelli M, Toffolatti L, Guglielmo M, Ripamonti CI, Cosmai L, Licitra L, Alfieri S
Oral Oncol 2023 Nov;146:106579. Epub 2023 Sep 29 doi: 10.1016/j.oraloncology.2023.106579. PMID: 37778228
Kiyota N, Tahara M, Fujii M
Jpn J Clin Oncol 2015 Jan;45(1):2-6. Epub 2014 Nov 19 doi: 10.1093/jjco/hyu195. PMID: 25411434
Sundvall M, Karrila A, Nordberg J, Grénman R, Elenius K
Expert Opin Emerg Drugs 2010 Jun;15(2):185-201. doi: 10.1517/14728211003716442. PMID: 20415599

Recent clinical studies

Etiology

Worakitchanon W, Panvongsa W, Siripoon T, Kitdumrongthum S, Wongpan A, Arsa L, Trachu N, Jinawath N, Chairoungdua A, Ngamphaiboon N
JCO Precis Oncol 2023 May;7:e2300003. doi: 10.1200/PO.23.00003. PMID: 37163716
Nindra U, Hurwitz J, Forstner D, Chin V, Gallagher R, Liu J
Cancer Med 2023 May;12(10):11234-11247. Epub 2023 Mar 19 doi: 10.1002/cam4.5815. PMID: 36934434Free PMC Article
Patil VM, Noronha V, Menon N, Singh A, Ghosh-Laskar S, Budrukkar A, Bhattacharjee A, Swain M, Mathrudev V, Nawale K, Balaji A, Peelay Z, Alone M, Pathak S, Mahajan A, Kumar S, Purandare N, Agarwal A, Puranik A, Pendse S, Reddy Yallala M, Sahu H, Kapu V, Dey S, Choudhary J, Krishna MR, Shetty A, Karuvandan N, Ravind R, Rai R, Jobanputra K, Chaturvedi P, Pai PS, Chaukar D, Nair S, Thiagarajan S, Prabhash K
J Clin Oncol 2023 May 1;41(13):2350-2361. Epub 2023 Jan 27 doi: 10.1200/JCO.22.00980. PMID: 36706347
Leidner R, Crittenden M, Young K, Xiao H, Wu Y, Couey MA, Patel AA, Cheng AC, Watters AL, Bifulco C, Morris G, Rushforth L, Nemeth S, Urba WJ, Gough M, Bell RB
J Immunother Cancer 2021 May;9(5) doi: 10.1136/jitc-2021-002485. PMID: 33963014Free PMC Article
Bourhis J, Sire C, Graff P, Grégoire V, Maingon P, Calais G, Gery B, Martin L, Alfonsi M, Desprez P, Pignon T, Bardet E, Rives M, Geoffrois L, Daly-Schveitzer N, Sen S, Tuchais C, Dupuis O, Guerif S, Lapeyre M, Favrel V, Hamoir M, Lusinchi A, Temam S, Pinna A, Tao YG, Blanchard P, Aupérin A
Lancet Oncol 2012 Feb;13(2):145-53. Epub 2012 Jan 18 doi: 10.1016/S1470-2045(11)70346-1. PMID: 22261362

Diagnosis

Worakitchanon W, Panvongsa W, Siripoon T, Kitdumrongthum S, Wongpan A, Arsa L, Trachu N, Jinawath N, Chairoungdua A, Ngamphaiboon N
JCO Precis Oncol 2023 May;7:e2300003. doi: 10.1200/PO.23.00003. PMID: 37163716
Erul E, Guven DC, Ozbay Y, Altunbulak AY, Kahvecioglu A, Ercan F, Yesil MF, Ucdal MT, Cengiz M, Yazici G, Kuscu O, Suslu N, Gullu I, Onur MR, Aksoy S
Biomark Med 2023 Jan;17(2):87-99. Epub 2023 Apr 12 doi: 10.2217/bmm-2022-0748. PMID: 37042459
Lin TC, Huang CH, Lien MY, Cheng FM, Li KC, Lin CY, Lin YC, Liang JA, Wang TH
Technol Cancer Res Treat 2022 Jan-Dec;21:15330338221107714. doi: 10.1177/15330338221107714. PMID: 35770906Free PMC Article
Li X, Fang Q, Du W, Zhang X, Dai L, Qiao Y
BMC Cancer 2021 May 27;21(1):622. doi: 10.1186/s12885-021-08373-8. PMID: 34044810Free PMC Article
Alorabi M, Shonka NA, Ganti AK
Crit Rev Oncol Hematol 2016 Mar;99:170-9. Epub 2015 Dec 19 doi: 10.1016/j.critrevonc.2015.12.006. PMID: 26797287

Therapy

Patil VM, Noronha V, Menon N, Singh A, Ghosh-Laskar S, Budrukkar A, Bhattacharjee A, Swain M, Mathrudev V, Nawale K, Balaji A, Peelay Z, Alone M, Pathak S, Mahajan A, Kumar S, Purandare N, Agarwal A, Puranik A, Pendse S, Reddy Yallala M, Sahu H, Kapu V, Dey S, Choudhary J, Krishna MR, Shetty A, Karuvandan N, Ravind R, Rai R, Jobanputra K, Chaturvedi P, Pai PS, Chaukar D, Nair S, Thiagarajan S, Prabhash K
J Clin Oncol 2023 May 1;41(13):2350-2361. Epub 2023 Jan 27 doi: 10.1200/JCO.22.00980. PMID: 36706347
Zhang Z, Wu B, Peng G, Xiao G, Huang J, Ding Q, Yang C, Xiong X, Ma H, Shi L, Yang J, Hong X, Wei J, Qin Y, Wan C, Zhong Y, Zhou Y, Zhao X, Leng Y, Zhang T, Wu G, Yao M, Zhang X, Yang K
Clin Cancer Res 2022 Aug 2;28(15):3268-3276. doi: 10.1158/1078-0432.CCR-22-0666. PMID: 35766967Free PMC Article
Leidner R, Crittenden M, Young K, Xiao H, Wu Y, Couey MA, Patel AA, Cheng AC, Watters AL, Bifulco C, Morris G, Rushforth L, Nemeth S, Urba WJ, Gough M, Bell RB
J Immunother Cancer 2021 May;9(5) doi: 10.1136/jitc-2021-002485. PMID: 33963014Free PMC Article
Machiels JP, Tao Y, Burtness B, Tahara M, Licitra L, Rischin D, Waldron J, Simon C, Gregoire V, Harrington K, Alves GV, Figueiredo Lima IP, Pointreau Y, M Hughes BG, Aksoy S, Hetnal M, Ge JY, Brown H, Cheng J, Bidadi B, Siu LL
Future Oncol 2020 Jun;16(18):1235-1243. Epub 2020 Jun 3 doi: 10.2217/fon-2020-0184. PMID: 32490686
Gyawali B, Shimokata T, Honda K, Ando Y
Cancer Treat Rev 2016 Mar;44:10-6. Epub 2016 Jan 22 doi: 10.1016/j.ctrv.2016.01.002. PMID: 26924194

Prognosis

Worakitchanon W, Panvongsa W, Siripoon T, Kitdumrongthum S, Wongpan A, Arsa L, Trachu N, Jinawath N, Chairoungdua A, Ngamphaiboon N
JCO Precis Oncol 2023 May;7:e2300003. doi: 10.1200/PO.23.00003. PMID: 37163716
Erul E, Guven DC, Ozbay Y, Altunbulak AY, Kahvecioglu A, Ercan F, Yesil MF, Ucdal MT, Cengiz M, Yazici G, Kuscu O, Suslu N, Gullu I, Onur MR, Aksoy S
Biomark Med 2023 Jan;17(2):87-99. Epub 2023 Apr 12 doi: 10.2217/bmm-2022-0748. PMID: 37042459
Li X, Fang Q, Du W, Zhang X, Dai L, Qiao Y
BMC Cancer 2021 May 27;21(1):622. doi: 10.1186/s12885-021-08373-8. PMID: 34044810Free PMC Article
Burgy M, Leblanc J, Borel C
Anticancer Drugs 2018 Apr;29(4):287-294. doi: 10.1097/CAD.0000000000000595. PMID: 29420335
Alorabi M, Shonka NA, Ganti AK
Crit Rev Oncol Hematol 2016 Mar;99:170-9. Epub 2015 Dec 19 doi: 10.1016/j.critrevonc.2015.12.006. PMID: 26797287

Clinical prediction guides

Oliveira G, Egloff AM, Afeyan AB, Wolff JO, Zeng Z, Chernock RD, Zhou L, Messier C, Lizotte P, Pfaff KL, Stromhaug K, Penter L, Haddad RI, Hanna GJ, Schoenfeld JD, Goguen LA, Annino DJ, Jo V, Oppelt P, Pipkorn P, Jackson R, Puram SV, Paniello RC, Rich JT, Webb J, Zevallos JP, Mansour M, Fu J, Dunn GP, Rodig SJ, Ley J, Morris LGT, Dunn L, Paweletz CP, Kallogjeri D, Piccirillo JF, Adkins DR, Wu CJ, Uppaluri R
Sci Immunol 2023 Sep 8;8(87):eadf4968. doi: 10.1126/sciimmunol.adf4968. PMID: 37683037Free PMC Article
Worakitchanon W, Panvongsa W, Siripoon T, Kitdumrongthum S, Wongpan A, Arsa L, Trachu N, Jinawath N, Chairoungdua A, Ngamphaiboon N
JCO Precis Oncol 2023 May;7:e2300003. doi: 10.1200/PO.23.00003. PMID: 37163716
Nindra U, Hurwitz J, Forstner D, Chin V, Gallagher R, Liu J
Cancer Med 2023 May;12(10):11234-11247. Epub 2023 Mar 19 doi: 10.1002/cam4.5815. PMID: 36934434Free PMC Article
Huang X, Liu Q, Zhong G, Peng Y, Liu Y, Liang L, Hong H, Feng W, Yang S, Zhang Y, Xian S, Li Z, Zhou Y, Zhang Z, Jiang W, Liang J, Liu ZG
J Exp Clin Cancer Res 2022 Oct 12;41(1):300. doi: 10.1186/s13046-022-02510-2. PMID: 36224603Free PMC Article
Liu K, Chen N, Wei J, Ma L, Yang S, Zhang X
Oncol Rep 2020 May;43(5):1525-1535. Epub 2020 Mar 9 doi: 10.3892/or.2020.7536. PMID: 32323844Free PMC Article

Recent systematic reviews

Nindra U, Hurwitz J, Forstner D, Chin V, Gallagher R, Liu J
Cancer Med 2023 May;12(10):11234-11247. Epub 2023 Mar 19 doi: 10.1002/cam4.5815. PMID: 36934434Free PMC Article
Desideri I, Becherini C, Belgioia L, Merlotti A, Ciccone LP, Franzese C, Loi M, De Felice F, Mazzola R, Caini S, Livi L, Bonomo P
Oral Oncol 2021 Aug;119:105355. Epub 2021 May 24 doi: 10.1016/j.oraloncology.2021.105355. PMID: 34044315
Tang WH, Sun W, Long GX
Medicine (Baltimore) 2020 Sep 4;99(36):e21785. doi: 10.1097/MD.0000000000021785. PMID: 32899005Free PMC Article
Bonomo P, Merlotti A, Olmetto E, Bianchi A, Desideri I, Bacigalupo A, Franco P, Franzese C, Orlandi E, Livi L, Caini S
Eur J Nucl Med Mol Imaging 2018 Nov;45(12):2122-2138. Epub 2018 Jun 9 doi: 10.1007/s00259-018-4065-5. PMID: 29948105Free PMC Article
Jacinto JK, Co J, Mejia MB, Regala EE
Br J Radiol 2017 Nov;90(1079):20170442. doi: 10.1259/bjr.20170442. PMID: 29053029Free PMC Article

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