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Locally Advanced Liver Carcinoma

MedGen UID:
1756794
Concept ID:
C5419077
Neoplastic Process

Definition

Liver carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

De Dosso S, Siebenhüner AR, Winder T, Meisel A, Fritsch R, Astaras C, Szturz P, Borner M
Cancer Treat Rev 2021 May;96:102180. Epub 2021 Mar 17 doi: 10.1016/j.ctrv.2021.102180. PMID: 33812339
Yang JD, Hainaut P, Gores GJ, Amadou A, Plymoth A, Roberts LR
Nat Rev Gastroenterol Hepatol 2019 Oct;16(10):589-604. Epub 2019 Aug 22 doi: 10.1038/s41575-019-0186-y. PMID: 31439937Free PMC Article
Fukuhara H, Ino Y, Todo T
Cancer Sci 2016 Oct;107(10):1373-1379. Epub 2016 Sep 9 doi: 10.1111/cas.13027. PMID: 27486853Free PMC Article

Recent clinical studies

Etiology

Alawyia B, Constantinou C
Curr Treat Options Oncol 2023 Jul;24(7):711-724. Epub 2023 Apr 27 doi: 10.1007/s11864-023-01098-9. PMID: 37103744
Nevola R, Ruocco R, Criscuolo L, Villani A, Alfano M, Beccia D, Imbriani S, Claar E, Cozzolino D, Sasso FC, Marrone A, Adinolfi LE, Rinaldi L
World J Gastroenterol 2023 Feb 28;29(8):1243-1260. doi: 10.3748/wjg.v29.i8.1243. PMID: 36925456Free PMC Article
Chiang CL, Chiu KWH, Chan KSK, Lee FAS, Li JCB, Wan CWS, Dai WC, Lam TC, Chen W, Wong NSM, Cheung ALY, Lee VWY, Lau VWH, El Helali A, Man K, Kong FMS, Lo CM, Chan AC
Lancet Gastroenterol Hepatol 2023 Feb;8(2):169-178. Epub 2022 Dec 15 doi: 10.1016/S2468-1253(22)00339-9. PMID: 36529152
Yang JD, Hainaut P, Gores GJ, Amadou A, Plymoth A, Roberts LR
Nat Rev Gastroenterol Hepatol 2019 Oct;16(10):589-604. Epub 2019 Aug 22 doi: 10.1038/s41575-019-0186-y. PMID: 31439937Free PMC Article
Llovet JM, Zucman-Rossi J, Pikarsky E, Sangro B, Schwartz M, Sherman M, Gores G
Nat Rev Dis Primers 2016 Apr 14;2:16018. doi: 10.1038/nrdp.2016.18. PMID: 27158749

Diagnosis

Zhou H, Song T
Biosci Trends 2021 Jul 6;15(3):155-160. Epub 2021 May 27 doi: 10.5582/bst.2021.01091. PMID: 34039818
Galle PR, Dufour JF, Peck-Radosavljevic M, Trojan J, Vogel A
Future Oncol 2021 Apr;17(10):1237-1251. Epub 2020 Dec 14 doi: 10.2217/fon-2020-0758. PMID: 33307782
Gordon-Walker TT, Bove K, Veldtman G
J Cardiol 2019 Sep;74(3):223-232. Epub 2019 Mar 28 doi: 10.1016/j.jjcc.2019.02.016. PMID: 30928109
Forner A, Reig M, Bruix J
Lancet 2018 Mar 31;391(10127):1301-1314. Epub 2018 Jan 5 doi: 10.1016/S0140-6736(18)30010-2. PMID: 29307467
Llovet JM, Zucman-Rossi J, Pikarsky E, Sangro B, Schwartz M, Sherman M, Gores G
Nat Rev Dis Primers 2016 Apr 14;2:16018. doi: 10.1038/nrdp.2016.18. PMID: 27158749

Therapy

Nevola R, Ruocco R, Criscuolo L, Villani A, Alfano M, Beccia D, Imbriani S, Claar E, Cozzolino D, Sasso FC, Marrone A, Adinolfi LE, Rinaldi L
World J Gastroenterol 2023 Feb 28;29(8):1243-1260. doi: 10.3748/wjg.v29.i8.1243. PMID: 36925456Free PMC Article
Oura K, Morishita A, Tani J, Masaki T
Int J Mol Sci 2021 May 28;22(11) doi: 10.3390/ijms22115801. PMID: 34071550Free PMC Article
Zhou H, Song T
Biosci Trends 2021 Jul 6;15(3):155-160. Epub 2021 May 27 doi: 10.5582/bst.2021.01091. PMID: 34039818
Forner A, Reig M, Bruix J
Lancet 2018 Mar 31;391(10127):1301-1314. Epub 2018 Jan 5 doi: 10.1016/S0140-6736(18)30010-2. PMID: 29307467
Llovet JM, Zucman-Rossi J, Pikarsky E, Sangro B, Schwartz M, Sherman M, Gores G
Nat Rev Dis Primers 2016 Apr 14;2:16018. doi: 10.1038/nrdp.2016.18. PMID: 27158749

Prognosis

Nevola R, Ruocco R, Criscuolo L, Villani A, Alfano M, Beccia D, Imbriani S, Claar E, Cozzolino D, Sasso FC, Marrone A, Adinolfi LE, Rinaldi L
World J Gastroenterol 2023 Feb 28;29(8):1243-1260. doi: 10.3748/wjg.v29.i8.1243. PMID: 36925456Free PMC Article
Zhou H, Song T
Biosci Trends 2021 Jul 6;15(3):155-160. Epub 2021 May 27 doi: 10.5582/bst.2021.01091. PMID: 34039818
Sangro B, Sarobe P, Hervás-Stubbs S, Melero I
Nat Rev Gastroenterol Hepatol 2021 Aug;18(8):525-543. Epub 2021 Apr 13 doi: 10.1038/s41575-021-00438-0. PMID: 33850328Free PMC Article
Gordon-Walker TT, Bove K, Veldtman G
J Cardiol 2019 Sep;74(3):223-232. Epub 2019 Mar 28 doi: 10.1016/j.jjcc.2019.02.016. PMID: 30928109
Llovet JM, Zucman-Rossi J, Pikarsky E, Sangro B, Schwartz M, Sherman M, Gores G
Nat Rev Dis Primers 2016 Apr 14;2:16018. doi: 10.1038/nrdp.2016.18. PMID: 27158749

Clinical prediction guides

Nevola R, Ruocco R, Criscuolo L, Villani A, Alfano M, Beccia D, Imbriani S, Claar E, Cozzolino D, Sasso FC, Marrone A, Adinolfi LE, Rinaldi L
World J Gastroenterol 2023 Feb 28;29(8):1243-1260. doi: 10.3748/wjg.v29.i8.1243. PMID: 36925456Free PMC Article
Chiang CL, Chiu KWH, Chan KSK, Lee FAS, Li JCB, Wan CWS, Dai WC, Lam TC, Chen W, Wong NSM, Cheung ALY, Lee VWY, Lau VWH, El Helali A, Man K, Kong FMS, Lo CM, Chan AC
Lancet Gastroenterol Hepatol 2023 Feb;8(2):169-178. Epub 2022 Dec 15 doi: 10.1016/S2468-1253(22)00339-9. PMID: 36529152
Oura K, Morishita A, Tani J, Masaki T
Int J Mol Sci 2021 May 28;22(11) doi: 10.3390/ijms22115801. PMID: 34071550Free PMC Article
Sangro B, Sarobe P, Hervás-Stubbs S, Melero I
Nat Rev Gastroenterol Hepatol 2021 Aug;18(8):525-543. Epub 2021 Apr 13 doi: 10.1038/s41575-021-00438-0. PMID: 33850328Free PMC Article
Gordon-Walker TT, Bove K, Veldtman G
J Cardiol 2019 Sep;74(3):223-232. Epub 2019 Mar 28 doi: 10.1016/j.jjcc.2019.02.016. PMID: 30928109

Recent systematic reviews

Meyers BM, Knox JJ, Liu DM, McLeod D, Ramjeesingh R, Tam VC, Lim HJ
Cancer Treat Rev 2023 Jul;118:102584. Epub 2023 May 27 doi: 10.1016/j.ctrv.2023.102584. PMID: 37336142
Glavas D, Bao QR, Scarpa M, Ruffolo C, Brown ZJ, Pawlik TM, Spolverato G
J Gastrointest Surg 2023 Apr;27(4):705-715. Epub 2023 Feb 16 doi: 10.1007/s11605-023-05621-z. PMID: 36797535Free PMC Article
Lv TR, Hu HJ, Regmi P, Liu F, Li FY
J Cancer Res Clin Oncol 2022 Jul;148(7):1685-1696. Epub 2022 Feb 24 doi: 10.1007/s00432-022-03949-8. PMID: 35201426
Tantai X, Liu Y, Yeo YH, Praktiknjo M, Mauro E, Hamaguchi Y, Engelmann C, Zhang P, Jeong JY, van Vugt JLA, Xiao H, Deng H, Gao X, Ye Q, Zhang J, Yang L, Cai Y, Liu Y, Liu N, Li Z, Han T, Kaido T, Sohn JH, Strassburg C, Berg T, Trebicka J, Hsu YC, IJzermans JNM, Wang J, Su GL, Ji F, Nguyen MH
J Hepatol 2022 Mar;76(3):588-599. Epub 2021 Nov 14 doi: 10.1016/j.jhep.2021.11.006. PMID: 34785325
Keane MG, Bramis K, Pereira SP, Fusai GK
World J Gastroenterol 2014 Mar 7;20(9):2267-78. doi: 10.3748/wjg.v20.i9.2267. PMID: 24605026Free PMC Article

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