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Sarcoma by AJCC Grade

MedGen UID:
233435
•Concept ID:
C1335919
•
Neoplastic Process
Synonym: AJCC Tumor Grade in Sarcoma

Professional guidelines

PubMed

Risk Assessment of Visceral Sarcomas: A Comparative Study of 2698 Cases from the SEER Database.
Dashti NK, Cates JMM
Ann Surg Oncol 2021 Oct;28(11):6852-6860. Epub 2021 Feb 4 doi: 10.1245/s10434-020-09576-2. PMID: 33538930
Management and outcomes among patients with sarcomatoid hepatocellular carcinoma: A population-based analysis.
Wu L, Tsilimigras DI, Farooq A, Hyer JM, Merath K, Paredes AZ, Mehta R, Sahara K, Shen F, Pawlik TM
Cancer 2019 Nov 1;125(21):3767-3775. Epub 2019 Jul 12 doi: 10.1002/cncr.32396. PMID: 31299092

Recent clinical studies

Etiology

Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma (KEYNOTE-716): distant metastasis-free survival results of a multicentre, double-blind, randomised, phase 3 trial.
Long GV, Luke JJ, Khattak MA, de la Cruz Merino L, Del Vecchio M, Rutkowski P, Spagnolo F, Mackiewicz J, Chiarion-Sileni V, Kirkwood JM, Robert C, Grob JJ, de Galitiis F, Schadendorf D, Carlino MS, Mohr P, Dummer R, Gershenwald JE, Yoon CH, Wu XL, Fukunaga-Kalabis M, Krepler C, Eggermont AMM, Ascierto PA; KEYNOTE-716 Investigators
Lancet Oncol 2022 Nov;23(11):1378-1388. Epub 2022 Oct 18 doi: 10.1016/S1470-2045(22)00559-9. PMID: 36265502
Secondary Malignancy in Giant Cell Tumor: A Single-Center Study.
Joo MW, Lee YS, Park HS, Chung YG, Yoon C
Curr Oncol 2022 Jun 2;29(6):4068-4080. doi: 10.3390/curroncol29060324. PMID: 35735433Free PMC Article
Evidence-based Tumor Staging of Skeletal Chondrosarcoma.
Compton ML, Cates JMM
Am J Surg Pathol 2020 Jan;44(1):111-119. doi: 10.1097/PAS.0000000000001397. PMID: 31651521
Spindle cell sarcoma: a SEER population-based analysis.
Feng L, Wang M, Yibulayin F, Zhang H, Yang YL, Ren F, Wushou A
Sci Rep 2018 Mar 22;8(1):5024. doi: 10.1038/s41598-018-23145-4. PMID: 29568070Free PMC Article
Soft tissue sarcomas.
Cormier JN, Pollock RE
CA Cancer J Clin 2004 Mar-Apr;54(2):94-109. doi: 10.3322/canjclin.54.2.94. PMID: 15061599

Diagnosis

Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma (KEYNOTE-716): distant metastasis-free survival results of a multicentre, double-blind, randomised, phase 3 trial.
Long GV, Luke JJ, Khattak MA, de la Cruz Merino L, Del Vecchio M, Rutkowski P, Spagnolo F, Mackiewicz J, Chiarion-Sileni V, Kirkwood JM, Robert C, Grob JJ, de Galitiis F, Schadendorf D, Carlino MS, Mohr P, Dummer R, Gershenwald JE, Yoon CH, Wu XL, Fukunaga-Kalabis M, Krepler C, Eggermont AMM, Ascierto PA; KEYNOTE-716 Investigators
Lancet Oncol 2022 Nov;23(11):1378-1388. Epub 2022 Oct 18 doi: 10.1016/S1470-2045(22)00559-9. PMID: 36265502
Comparison of the AJCC, MSTS, and Modified Spanier Systems for Clinical and Pathologic Staging of Osteosarcoma.
Cates JM
Am J Surg Pathol 2017 Mar;41(3):405-413. doi: 10.1097/PAS.0000000000000774. PMID: 28195881
Staging soft tissue sarcoma: evolution and change.
Kotilingam D, Lev DC, Lazar AJ, Pollock RE
CA Cancer J Clin 2006 Sep-Oct;56(5):282-91; quiz 314-5. doi: 10.3322/canjclin.56.5.282. PMID: 17005597
Soft tissue sarcomas.
Cormier JN, Pollock RE
CA Cancer J Clin 2004 Mar-Apr;54(2):94-109. doi: 10.3322/canjclin.54.2.94. PMID: 15061599
Prognostic factors in soft tissue sarcoma.
Levine EA
Semin Surg Oncol 1999 Jul-Aug;17(1):23-32. doi: 10.1002/(sici)1098-2388(199907/08)17:1<23::aid-ssu4>3.0.co;2-r. PMID: 10402635

Therapy

Development and validation of a nomogram for predicting prognosis of high-grade chondrosarcoma: A surveillance, epidemiology, and end results-based population analysis.
Sun Y, Ouyang C, Zhang Y, Li Y, Liu Y, Jiang M, Nong L, Gao G
J Orthop Surg (Hong Kong) 2023 May-Aug;31(2):10225536231174255. doi: 10.1177/10225536231174255. PMID: 37147017
Prognostic nomogram in patients with epithelioid sarcoma: A SEER-based study.
Zhang D, Hu J, Liu Z, Wu H, Cheng H, Li C
Cancer Med 2023 Feb;12(3):3079-3088. Epub 2022 Sep 8 doi: 10.1002/cam4.5230. PMID: 36073670Free PMC Article
Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma (KEYNOTE-716): distant metastasis-free survival results of a multicentre, double-blind, randomised, phase 3 trial.
Long GV, Luke JJ, Khattak MA, de la Cruz Merino L, Del Vecchio M, Rutkowski P, Spagnolo F, Mackiewicz J, Chiarion-Sileni V, Kirkwood JM, Robert C, Grob JJ, de Galitiis F, Schadendorf D, Carlino MS, Mohr P, Dummer R, Gershenwald JE, Yoon CH, Wu XL, Fukunaga-Kalabis M, Krepler C, Eggermont AMM, Ascierto PA; KEYNOTE-716 Investigators
Lancet Oncol 2022 Nov;23(11):1378-1388. Epub 2022 Oct 18 doi: 10.1016/S1470-2045(22)00559-9. PMID: 36265502
A novel nomogram for predicting cancer-specific survival in women with uterine sarcoma: a large population-based study.
Li YJ, Lyu J, Li C, He HR, Wang JF, Wang YL, Fang J, Ji J
BMC Womens Health 2022 May 14;22(1):175. doi: 10.1186/s12905-022-01739-5. PMID: 35568940Free PMC Article
Identifying the Prognosis Factors and Predicting the Survival Probability in Patients with Non-Metastatic Chondrosarcoma from the SEER Database.
Huang R, Sun Z, Zheng H, Yan P, Hu P, Yin H, Zhang J, Meng T, Huang Z
Orthop Surg 2019 Oct;11(5):801-810. doi: 10.1111/os.12521. PMID: 31663279Free PMC Article

Prognosis

Secondary Malignancy in Giant Cell Tumor: A Single-Center Study.
Joo MW, Lee YS, Park HS, Chung YG, Yoon C
Curr Oncol 2022 Jun 2;29(6):4068-4080. doi: 10.3390/curroncol29060324. PMID: 35735433Free PMC Article
Evidence-based Tumor Staging of Skeletal Chondrosarcoma.
Compton ML, Cates JMM
Am J Surg Pathol 2020 Jan;44(1):111-119. doi: 10.1097/PAS.0000000000001397. PMID: 31651521
H3K27me3 and VEGF is associated with poor prognosis in patients with synovial sarcoma.
Diao Y, Zhang P, Dai R, Xu J, Feng H
Pathol Res Pract 2018 Jul;214(7):974-977. Epub 2018 May 20 doi: 10.1016/j.prp.2018.05.015. PMID: 29803658
Staging soft tissue sarcoma: evolution and change.
Kotilingam D, Lev DC, Lazar AJ, Pollock RE
CA Cancer J Clin 2006 Sep-Oct;56(5):282-91; quiz 314-5. doi: 10.3322/canjclin.56.5.282. PMID: 17005597
Soft tissue sarcomas.
Cormier JN, Pollock RE
CA Cancer J Clin 2004 Mar-Apr;54(2):94-109. doi: 10.3322/canjclin.54.2.94. PMID: 15061599

Clinical prediction guides

Prognostic nomogram in patients with epithelioid sarcoma: A SEER-based study.
Zhang D, Hu J, Liu Z, Wu H, Cheng H, Li C
Cancer Med 2023 Feb;12(3):3079-3088. Epub 2022 Sep 8 doi: 10.1002/cam4.5230. PMID: 36073670Free PMC Article
Clinical Characteristics, Prognostic Factor and a Novel Dynamic Prediction Model for Overall Survival of Elderly Patients With Chondrosarcoma: A Population-Based Study.
Tong Y, Cui Y, Jiang L, Pi Y, Gong Y, Zhao D
Front Public Health 2022;10:901680. Epub 2022 Jun 30 doi: 10.3389/fpubh.2022.901680. PMID: 35844853Free PMC Article
Secondary Malignancy in Giant Cell Tumor: A Single-Center Study.
Joo MW, Lee YS, Park HS, Chung YG, Yoon C
Curr Oncol 2022 Jun 2;29(6):4068-4080. doi: 10.3390/curroncol29060324. PMID: 35735433Free PMC Article
Evidence-based Tumor Staging of Skeletal Chondrosarcoma.
Compton ML, Cates JMM
Am J Surg Pathol 2020 Jan;44(1):111-119. doi: 10.1097/PAS.0000000000001397. PMID: 31651521
Comparison of the AJCC, MSTS, and Modified Spanier Systems for Clinical and Pathologic Staging of Osteosarcoma.
Cates JM
Am J Surg Pathol 2017 Mar;41(3):405-413. doi: 10.1097/PAS.0000000000000774. PMID: 28195881

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