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Minor salivary gland carcinoma

MedGen UID:
233710
•Concept ID:
C1334771
•
Neoplastic Process
Synonyms: Carcinoma of Minor Salivary Gland; carcinoma of minor salivary gland; Carcinoma of the Minor Salivary Gland; carcinoma of the minor salivary gland; minor salivary gland cancer; Minor Salivary Gland Carcinoma; minor salivary gland carcinoma
 
Monarch Initiative: MONDO:0045069

Definition

A carcinoma that arises from the minor salivary glands. Representative examples include adenoid cystic carcinoma, acinic cell carcinoma, polymorphous low grade adenocarcinoma, and mucinous adenocarcinoma. [from NCI]

Professional guidelines

PubMed

Recent trends in the management of minor salivary gland carcinoma.
Vander Poorten V, Hunt J, Bradley PJ, Haigentz M Jr, Rinaldo A, Mendenhall WM, Suarez C, Silver C, Takes RP, Ferlito A
Head Neck 2014 Mar;36(3):444-55. Epub 2013 Apr 4 doi: 10.1002/hed.23249. PMID: 23559518
Long-term treatment outcome of minor salivary gland carcinoma of the hard palate.
Li Q, Zhang XR, Liu XK, Liu ZM, Liu WW, Li H, Guo ZM
Oral Oncol 2012 May;48(5):456-62. Epub 2012 Jan 16 doi: 10.1016/j.oraloncology.2011.12.005. PMID: 22248739

Recent clinical studies

Etiology

Salivary gland polymorphous adenocarcinoma: Clinicopathological features and gene alterations in 36 Japanese patients.
Fukumura M, Ishibashi K, Nakaguro M, Nagao T, Saida K, Urano M, Tanigawa M, Hirai H, Yagyuu T, Kikuchi K, Yada N, Sugita Y, Miyabe M, Hasegawa S, Goto M, Yamamoto H, Ohuchi T, Kusafuka K, Ogawa I, Suzuki H, Notohara K, Shimoda M, Tada Y, Kirita T, Takata T, Morinaga S, Maeda H, Warnakulasuriya S, Miyabe S, Nagao T
J Oral Pathol Med 2022 Sep;51(8):710-720. Epub 2022 Aug 15 doi: 10.1111/jop.13336. PMID: 35880805
Minor Salivary Gland Carcinoma of the Oropharynx: A Population-Based Analysis of 1426 Patients.
Goel AN, Badran KW, Braun APG, Garrett AM, Long JL
Otolaryngol Head Neck Surg 2018 Feb;158(2):287-294. Epub 2017 Oct 3 doi: 10.1177/0194599817735309. PMID: 28971745
Minor salivary gland carcinoma: a review of 35 cases.
Haymerle G, Schneider S, Harris L, Häupl T, Schopper C, Pammer J, Grasl MCh, Erovic BM
Eur Arch Otorhinolaryngol 2016 Sep;273(9):2717-26. Epub 2015 Oct 23 doi: 10.1007/s00405-015-3805-4. PMID: 26498950
Recent trends in the management of minor salivary gland carcinoma.
Vander Poorten V, Hunt J, Bradley PJ, Haigentz M Jr, Rinaldo A, Mendenhall WM, Suarez C, Silver C, Takes RP, Ferlito A
Head Neck 2014 Mar;36(3):444-55. Epub 2013 Apr 4 doi: 10.1002/hed.23249. PMID: 23559518
Minor salivary gland carcinomas of oral cavity and oropharynx.
Chijiwa H, Sakamoto K, Umeno H, Nakashima T, Suzuki G, Hayafuchi N
J Laryngol Otol Suppl 2009;(31):52-7. doi: 10.1017/S002221510900509X. PMID: 19460205

Diagnosis

Salivary gland polymorphous adenocarcinoma: Clinicopathological features and gene alterations in 36 Japanese patients.
Fukumura M, Ishibashi K, Nakaguro M, Nagao T, Saida K, Urano M, Tanigawa M, Hirai H, Yagyuu T, Kikuchi K, Yada N, Sugita Y, Miyabe M, Hasegawa S, Goto M, Yamamoto H, Ohuchi T, Kusafuka K, Ogawa I, Suzuki H, Notohara K, Shimoda M, Tada Y, Kirita T, Takata T, Morinaga S, Maeda H, Warnakulasuriya S, Miyabe S, Nagao T
J Oral Pathol Med 2022 Sep;51(8):710-720. Epub 2022 Aug 15 doi: 10.1111/jop.13336. PMID: 35880805
Lymph node ratio as a predictor for minor salivary gland cancer in head and neck.
Suzuki H, Sasaki E, Takano G, Goto S, Nishikawa D, Beppu S, Terada H, Sawabe M, Hanai N
BMC Cancer 2021 Nov 6;21(1):1186. doi: 10.1186/s12885-021-08877-3. PMID: 34742280Free PMC Article
Prediction of Minor Salivary Gland Carcinoma: A Novel Nomogram and Risk Classification System for Overall Survival and Cancer-Specific Survival.
Lan LF, Gao CK, Ma CW
Otolaryngol Head Neck Surg 2021 Feb;164(2):359-368. Epub 2020 Jul 21 doi: 10.1177/0194599820938323. PMID: 32692284
Recent trends in the management of minor salivary gland carcinoma.
Vander Poorten V, Hunt J, Bradley PJ, Haigentz M Jr, Rinaldo A, Mendenhall WM, Suarez C, Silver C, Takes RP, Ferlito A
Head Neck 2014 Mar;36(3):444-55. Epub 2013 Apr 4 doi: 10.1002/hed.23249. PMID: 23559518
Minor salivary gland carcinoma involving the oral cavity or oropharynx.
Hyam DM, Veness MJ, Morgan GJ
Aust Dent J 2004 Mar;49(1):16-9. doi: 10.1111/j.1834-7819.2004.tb00044.x. PMID: 15104129

Therapy

Prediction of Minor Salivary Gland Carcinoma: A Novel Nomogram and Risk Classification System for Overall Survival and Cancer-Specific Survival.
Lan LF, Gao CK, Ma CW
Otolaryngol Head Neck Surg 2021 Feb;164(2):359-368. Epub 2020 Jul 21 doi: 10.1177/0194599820938323. PMID: 32692284
Phase II trial of 4'-epi-doxorubicin in advanced carcinoma of head and neck origin.
Magee MJ, Howard J, Bosl GJ, Wittes RE
Cancer Treat Rep 1985 Jan;69(1):125-6. PMID: 3855384

Prognosis

Salivary gland polymorphous adenocarcinoma: Clinicopathological features and gene alterations in 36 Japanese patients.
Fukumura M, Ishibashi K, Nakaguro M, Nagao T, Saida K, Urano M, Tanigawa M, Hirai H, Yagyuu T, Kikuchi K, Yada N, Sugita Y, Miyabe M, Hasegawa S, Goto M, Yamamoto H, Ohuchi T, Kusafuka K, Ogawa I, Suzuki H, Notohara K, Shimoda M, Tada Y, Kirita T, Takata T, Morinaga S, Maeda H, Warnakulasuriya S, Miyabe S, Nagao T
J Oral Pathol Med 2022 Sep;51(8):710-720. Epub 2022 Aug 15 doi: 10.1111/jop.13336. PMID: 35880805
ELMO3 - a Negative Prognostic Marker in Minor Salivary Gland Carcinoma.
Kotowski U, Kadletz L, Schneider S, Oberndorfer F, Erovic BM, Grasl MC, Lill C, Heiduschka G
Pathol Oncol Res 2019 Apr;25(2):585-591. Epub 2018 Oct 29 doi: 10.1007/s12253-018-0475-8. PMID: 30374620Free PMC Article
Minor Salivary Gland Carcinoma of the Oropharynx: A Population-Based Analysis of 1426 Patients.
Goel AN, Badran KW, Braun APG, Garrett AM, Long JL
Otolaryngol Head Neck Surg 2018 Feb;158(2):287-294. Epub 2017 Oct 3 doi: 10.1177/0194599817735309. PMID: 28971745
Minor salivary gland carcinoma: a review of 35 cases.
Haymerle G, Schneider S, Harris L, Häupl T, Schopper C, Pammer J, Grasl MCh, Erovic BM
Eur Arch Otorhinolaryngol 2016 Sep;273(9):2717-26. Epub 2015 Oct 23 doi: 10.1007/s00405-015-3805-4. PMID: 26498950
Recent trends in the management of minor salivary gland carcinoma.
Vander Poorten V, Hunt J, Bradley PJ, Haigentz M Jr, Rinaldo A, Mendenhall WM, Suarez C, Silver C, Takes RP, Ferlito A
Head Neck 2014 Mar;36(3):444-55. Epub 2013 Apr 4 doi: 10.1002/hed.23249. PMID: 23559518

Clinical prediction guides

Elective Neck Dissection Improves Regional Control in cN0 Minor Salivary Gland Carcinoma in the Oral Cavity.
Gu H, Zhou Y, Xuan G, Wang Y, Chen M
J Oral Maxillofac Surg 2023 Apr;81(4):504-510. Epub 2022 Dec 30 doi: 10.1016/j.joms.2022.12.012. PMID: 36592935
Prediction of Minor Salivary Gland Carcinoma: A Novel Nomogram and Risk Classification System for Overall Survival and Cancer-Specific Survival.
Lan LF, Gao CK, Ma CW
Otolaryngol Head Neck Surg 2021 Feb;164(2):359-368. Epub 2020 Jul 21 doi: 10.1177/0194599820938323. PMID: 32692284
ELMO3 - a Negative Prognostic Marker in Minor Salivary Gland Carcinoma.
Kotowski U, Kadletz L, Schneider S, Oberndorfer F, Erovic BM, Grasl MC, Lill C, Heiduschka G
Pathol Oncol Res 2019 Apr;25(2):585-591. Epub 2018 Oct 29 doi: 10.1007/s12253-018-0475-8. PMID: 30374620Free PMC Article
Survival in oral cavity minor salivary gland carcinoma.
Kakarala K, Bhattacharyya N
Otolaryngol Head Neck Surg 2010 Jul;143(1):122-6. doi: 10.1016/j.otohns.2010.02.033. PMID: 20620630
Minor salivary gland carcinomas of oral cavity and oropharynx.
Chijiwa H, Sakamoto K, Umeno H, Nakashima T, Suzuki G, Hayafuchi N
J Laryngol Otol Suppl 2009;(31):52-7. doi: 10.1017/S002221510900509X. PMID: 19460205

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