U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Malignant Mixed Mesodermal (Mullerian) Tumor

MedGen UID:
277336
•Concept ID:
C1334603
•
Neoplastic Process
Synonyms: Mesodermal Mixed Tumor; Mesodermal Mixed Tumors; Mixed Tumor, Mesodermal; Mixed Tumors, Mesodermal; Tumor, Mesodermal Mixed; Tumors, Mesodermal Mixed
SNOMED CT: Mullerian mixed tumor (63264007); Malignant mixed mesodermal tumor (63264007); Mesodermal mixed tumor (63264007)

Definition

An aggressive malignant tumor of the female reproductive system, affecting predominantly elderly menopausal women. The endometrium and ovary are the most common sites of tumor origin. Morphologically, it is a high grade tumor, composed of carcinomatous and sarcomatous elements. [from NCI]

Professional guidelines

PubMed

Tamoxifen treatment for breast cancer and risk of endometrial cancer: a case-control study.
Swerdlow AJ, Jones ME; British Tamoxifen Second Cancer Study Group
J Natl Cancer Inst 2005 Mar 2;97(5):375-84. doi: 10.1093/jnci/dji057. PMID: 15741574
Uterine sarcomas: prognostic factors and treatment modalities--study on 209 patients.
George M, Pejovic MH, Kramar A
Gynecol Oncol 1986 May;24(1):58-67. doi: 10.1016/0090-8258(86)90008-9. PMID: 3699577

Recent clinical studies

Etiology

Sarcomatoid carcinoma with osseous differentiation in the bladder.
Arenas LF, Fontes DA, Pereira EM, Hering FL
Int Braz J Urol 2006 Sep-Oct;32(5):563-5. doi: 10.1590/s1677-55382006000500010. PMID: 17081326
Platinum-based combination chemotherapy for malignant mixed mesodermal tumors of the ovary.
Andersen WA, Young DE, Peters WA 3rd, Smith EB, Bagley CM, Taylor PT Jr
Gynecol Oncol 1989 Mar;32(3):319-22. doi: 10.1016/0090-8258(89)90632-x. PMID: 2537779

Diagnosis

Platinum-based combination chemotherapy for malignant mixed mesodermal tumors of the ovary.
Andersen WA, Young DE, Peters WA 3rd, Smith EB, Bagley CM, Taylor PT Jr
Gynecol Oncol 1989 Mar;32(3):319-22. doi: 10.1016/0090-8258(89)90632-x. PMID: 2537779

Therapy

Sarcomatoid carcinoma with osseous differentiation in the bladder.
Arenas LF, Fontes DA, Pereira EM, Hering FL
Int Braz J Urol 2006 Sep-Oct;32(5):563-5. doi: 10.1590/s1677-55382006000500010. PMID: 17081326
Platinum-based combination chemotherapy for malignant mixed mesodermal tumors of the ovary.
Andersen WA, Young DE, Peters WA 3rd, Smith EB, Bagley CM, Taylor PT Jr
Gynecol Oncol 1989 Mar;32(3):319-22. doi: 10.1016/0090-8258(89)90632-x. PMID: 2537779

Prognosis

Primary peritoneal malignant mixed mesodermal (Müllerian) tumor.
Hussein MR, Hussein SR, Abd-Elwahed AR
Tumori 2009 Jul-Aug;95(4):525-31. doi: 10.1177/030089160909500421. PMID: 19856669
Sarcomatoid carcinoma with osseous differentiation in the bladder.
Arenas LF, Fontes DA, Pereira EM, Hering FL
Int Braz J Urol 2006 Sep-Oct;32(5):563-5. doi: 10.1590/s1677-55382006000500010. PMID: 17081326
Primary mesenteric malignant mixed mesodermal (müllerian) tumor with neuroendocrine differentiation.
Cokelaere K, Michielsen P, De Vos R, Sciot R
Mod Pathol 2001 May;14(5):515-20. doi: 10.1038/modpathol.3880340. PMID: 11353063

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...