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Laryngeal Undifferentiated Carcinoma

MedGen UID:
473543
Concept ID:
C2188069
Neoplastic Process

Definition

An undifferentiated carcinoma that arises from the larynx. This category includes lymphoepithelial carcinoma and giant cell carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLaryngeal Undifferentiated Carcinoma

Professional guidelines

PubMed

Grégoire V, Evans M, Le QT, Bourhis J, Budach V, Chen A, Eisbruch A, Feng M, Giralt J, Gupta T, Hamoir M, Helito JK, Hu C, Hunter K, Johansen J, Kaanders J, Laskar SG, Lee A, Maingon P, Mäkitie A, Micciche' F, Nicolai P, O'Sullivan B, Poitevin A, Porceddu S, Składowski K, Tribius S, Waldron J, Wee J, Yao M, Yom SS, Zimmermann F, Grau C
Radiother Oncol 2018 Jan;126(1):3-24. Epub 2017 Nov 24 doi: 10.1016/j.radonc.2017.10.016. PMID: 29180076
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Recent clinical studies

Etiology

Lahav Y, Cohen O, Huszar M, Levy I, Cata JP, Halperin D, Shoffel-Havakuk H
J Voice 2023 May;37(3):433-439. Epub 2021 Mar 7 doi: 10.1016/j.jvoice.2021.02.018. PMID: 33750623
Richards HW, Bertelsen C, Hamilton B, Sauer D, Schindler J
Ann Otol Rhinol Laryngol 2022 Dec;131(12):1398-1403. Epub 2022 Jan 6 doi: 10.1177/00034894211069459. PMID: 34991344
Petruzzi G, Costantino A, De Virgilio A, Zocchi J, Campo F, Mercante G, Spriano G, Pellini R
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1157-1166. Epub 2021 Aug 2 doi: 10.1007/s00405-021-07011-0. PMID: 34338877
Machiels JP, René Leemans C, Golusinski W, Grau C, Licitra L, Gregoire V; EHNS Executive Board. Electronic address: secretariat@ehns.org; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org; ESTRO Executive Board. Electronic address: info@estro.org
Ann Oncol 2020 Nov;31(11):1462-1475. Epub 2020 Oct 23 doi: 10.1016/j.annonc.2020.07.011. PMID: 33239190
Forastiere AA, Zhang Q, Weber RS, Maor MH, Goepfert H, Pajak TF, Morrison W, Glisson B, Trotti A, Ridge JA, Thorstad W, Wagner H, Ensley JF, Cooper JS
J Clin Oncol 2013 Mar 1;31(7):845-52. Epub 2012 Nov 26 doi: 10.1200/JCO.2012.43.6097. PMID: 23182993Free PMC Article

Diagnosis

Lechien JR, Vaira LA, Chiesa-Estomba CM
Curr Opin Otolaryngol Head Neck Surg 2024 Apr 1;32(2):118-124. Epub 2023 Oct 10 doi: 10.1097/MOO.0000000000000910. PMID: 37820109
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Richards HW, Bertelsen C, Hamilton B, Sauer D, Schindler J
Ann Otol Rhinol Laryngol 2022 Dec;131(12):1398-1403. Epub 2022 Jan 6 doi: 10.1177/00034894211069459. PMID: 34991344
Machiels JP, René Leemans C, Golusinski W, Grau C, Licitra L, Gregoire V; EHNS Executive Board. Electronic address: secretariat@ehns.org; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org; ESTRO Executive Board. Electronic address: info@estro.org
Ann Oncol 2020 Nov;31(11):1462-1475. Epub 2020 Oct 23 doi: 10.1016/j.annonc.2020.07.011. PMID: 33239190
Hunt JL, Ferlito A, Hellquist H, Rinaldo A, Skálová A, Slootweg PJ, Willems SM, Cardesa A
Adv Anat Pathol 2017 May;24(3):161-168. doi: 10.1097/PAP.0000000000000147. PMID: 28338500

Therapy

Yang W, Yang Y, Guo Y, Guo J, Ma M, Han B
Front Endocrinol (Lausanne) 2023;14:1197730. Epub 2023 Aug 29 doi: 10.3389/fendo.2023.1197730. PMID: 37711902Free PMC Article
Bourhis J, Burtness B, Licitra LF, Nutting C, Schoenfeld JD, Omar M, Bouisset F, Nauwelaerts H, Urfer Y, Zanna C, Cohen EE
Future Oncol 2022 May;18(14):1669-1678. Epub 2022 Feb 17 doi: 10.2217/fon-2021-1634. PMID: 35172587
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Forastiere AA, Zhang Q, Weber RS, Maor MH, Goepfert H, Pajak TF, Morrison W, Glisson B, Trotti A, Ridge JA, Thorstad W, Wagner H, Ensley JF, Cooper JS
J Clin Oncol 2013 Mar 1;31(7):845-52. Epub 2012 Nov 26 doi: 10.1200/JCO.2012.43.6097. PMID: 23182993Free PMC Article
Jackson BS, Rosenthall L, Attia E
Laryngoscope 1981 Dec;91(12):2085-91. doi: 10.1288/00005537-198112000-00010. PMID: 6459505

Prognosis

Petruzzi G, Costantino A, De Virgilio A, Zocchi J, Campo F, Mercante G, Spriano G, Pellini R
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1157-1166. Epub 2021 Aug 2 doi: 10.1007/s00405-021-07011-0. PMID: 34338877
Machiels JP, René Leemans C, Golusinski W, Grau C, Licitra L, Gregoire V; EHNS Executive Board. Electronic address: secretariat@ehns.org; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org; ESTRO Executive Board. Electronic address: info@estro.org
Ann Oncol 2020 Nov;31(11):1462-1475. Epub 2020 Oct 23 doi: 10.1016/j.annonc.2020.07.011. PMID: 33239190
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Cordes S, Halum S, Hansen L
Otolaryngol Head Neck Surg 2013 Nov;149(5):733-8. Epub 2013 Jul 26 doi: 10.1177/0194599813497921. PMID: 23894146
Forastiere AA, Zhang Q, Weber RS, Maor MH, Goepfert H, Pajak TF, Morrison W, Glisson B, Trotti A, Ridge JA, Thorstad W, Wagner H, Ensley JF, Cooper JS
J Clin Oncol 2013 Mar 1;31(7):845-52. Epub 2012 Nov 26 doi: 10.1200/JCO.2012.43.6097. PMID: 23182993Free PMC Article

Clinical prediction guides

Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Han H, Lyu Q, Zhao J
Ear Nose Throat J 2022 May;101(4):NP158-NP163. Epub 2020 Aug 31 doi: 10.1177/0145561320953232. PMID: 32865459
Chen L, Chen Q, Li C, Zhou L, Wang S, Zhang M
ORL J Otorhinolaryngol Relat Spec 2020;82(6):310-317. Epub 2020 Sep 2 doi: 10.1159/000508134. PMID: 32877904
Chen L, Deng W, Li C, Lau H, Tao L, Wang S, Zhou L, Zhang M
Acta Otolaryngol 2020 Feb;140(2):195-201. Epub 2019 Dec 18 doi: 10.1080/00016489.2019.1700305. PMID: 31852360
Wenig BM
Semin Diagn Pathol 2015 Jan;32(1):74-86. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.004. PMID: 25804344

Recent systematic reviews

Lechien JR, Hans S
J Otolaryngol Head Neck Surg 2023 Dec 13;52(1):81. doi: 10.1186/s40463-023-00666-1. PMID: 38093339Free PMC Article
Russo E, Costantino A, Veneroni MV, Festa BM, Pellini R, Campo F, Petruzzi G, Spriano G, Mercante G, De Virgilio A
Laryngoscope 2023 Jun;133(6):1425-1433. Epub 2022 Aug 4 doi: 10.1002/lary.30332. PMID: 37158265
Petruzzi G, Costantino A, De Virgilio A, Zocchi J, Campo F, Mercante G, Spriano G, Pellini R
Eur Arch Otorhinolaryngol 2022 Mar;279(3):1157-1166. Epub 2021 Aug 2 doi: 10.1007/s00405-021-07011-0. PMID: 34338877
Echanique KA, Desai SV, Marchiano E, Spinazzi EF, Strojan P, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2017 Jan;156(1):38-45. Epub 2016 Aug 9 doi: 10.1177/0194599816662631. PMID: 27484231
Marchiano E, Chin OY, Fang CH, Park RC, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2016 Mar;154(3):433-9. Epub 2015 Dec 23 doi: 10.1177/0194599815621884. PMID: 26701176

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