U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Upper tract urothelial carcinoma

MedGen UID:
67388
Concept ID:
C0220648
Neoplastic Process
Synonyms: Renal Pelvis and Ureter Transitional Cell Cancer; Renal Pelvis and Ureter Transitional Cell Carcinoma; Renal Pelvis and Ureter Urothelial Carcinoma; TCC of Renal Pelvis and Ureter; Transitional Cell Cancer of Renal Pelvis and Ureter; Transitional Cell Cancer of the Renal Pelvis and Ureter; Transitional Cell Carcinoma of Renal Pelvis and Ureter; Transitional cell carcinoma of upper urinary tract; Upper Urinary Tract Urothelial Carcinoma; Urothelial Carcinoma of the Renal Pelvis and Ureter; Urothelial Carcinoma of the Upper Urinary Tract; Urothelial carcinoma of upper urinary tract
SNOMED CT: Transitional cell carcinoma of upper urinary tract (1208451008); Urothelial carcinoma of upper urinary tract (1208451008)

Definition

A urothelial carcinoma that arises from the renal pelvis and ureter. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUpper tract urothelial carcinoma

Professional guidelines

PubMed

Claps F, Pavan N, Ongaro L, Tierno D, Grassi G, Trombetta C, Tulone G, Simonato A, Bartoletti R, Mertens LS, van Rhijn BWG, Mir MC, Scaggiante B
Int J Mol Sci 2023 Aug 9;24(16) doi: 10.3390/ijms241612596. PMID: 37628785Free PMC Article
Tay LJ, Chatterton K, Colemeadow J, Nair R, Bultitude M, Thomas K
BJU Int 2020 Jul;126(1):5-6. doi: 10.1111/bju.15068. PMID: 32248617
Flaig TW, Spiess PE, Agarwal N, Bangs R, Boorjian SA, Buyyounouski MK, Chang S, Downs TM, Efstathiou JA, Friedlander T, Greenberg RE, Guru KA, Guzzo T, Herr HW, Hoffman-Censits J, Hoimes C, Inman BA, Jimbo M, Kader AK, Lele SM, Michalski J, Montgomery JS, Nandagopal L, Pagliaro LC, Pal SK, Patterson A, Plimack ER, Pohar KS, Preston MA, Sexton WJ, Siefker-Radtke AO, Tward J, Wright JL, Gurski LA, Johnson-Chilla A
J Natl Compr Canc Netw 2020 Mar;18(3):329-354. doi: 10.6004/jnccn.2020.0011. PMID: 32135513

Recent clinical studies

Etiology

Qu Y, Yao Z, Xu N, Shi G, Su J, Ye S, Chang K, Li K, Wang Y, Tan S, Pei X, Chen Y, Qin Z, Feng J, Lv J, Zhu J, Ma F, Tang S, Xu W, Tian X, Anwaier A, Tian S, Xu W, Wu X, Zhu S, Zhu Y, Cao D, Sun M, Gan H, Zhao J, Zhang H, Ye D, Ding C
Cell Rep Med 2023 Sep 19;4(9):101166. Epub 2023 Aug 25 doi: 10.1016/j.xcrm.2023.101166. PMID: 37633276Free PMC Article
Lonati C, Suardi N
Eur Urol 2022 Nov;82(5):574. Epub 2022 Aug 12 doi: 10.1016/j.eururo.2022.07.031. PMID: 35965207
Joseph JP, O'Malley P, Su LM
J Endourol 2021 Sep;35(S2):S122-S131. doi: 10.1089/end.2020.1074. PMID: 34499556
Leow JJ, Chong YL, Chang SL, Valderrama BP, Powles T, Bellmunt J
Eur Urol 2021 May;79(5):635-654. Epub 2020 Aug 12 doi: 10.1016/j.eururo.2020.07.003. PMID: 32798146
Lucca I, Leow JJ, Shariat SF, Chang SL
Hematol Oncol Clin North Am 2015 Apr;29(2):271-88, ix. Epub 2014 Dec 17 doi: 10.1016/j.hoc.2014.10.003. PMID: 25836934

Diagnosis

Teoh JY, Kamat AM, Black PC, Grivas P, Shariat SF, Babjuk M
Nat Rev Urol 2022 May;19(5):280-294. Epub 2022 Mar 31 doi: 10.1038/s41585-022-00578-1. PMID: 35361927
Li Z, Xu H, Gong Y, Chen W, Zhan Y, Yu L, Sun Y, Li A, He S, Guan B, Wu Y, Xiong G, Fang D, He Y, Tang Q, Yao L, Hu Z, Mei H, He Z, Cai Z, Guo Y, Li X, Zhou L, Huang W
Adv Sci (Weinh) 2022 Feb;9(4):e2103999. Epub 2021 Dec 16 doi: 10.1002/advs.202103999. PMID: 34914855Free PMC Article
Tay LJ, Chatterton K, Colemeadow J, Nair R, Bultitude M, Thomas K
BJU Int 2020 Jul;126(1):5-6. doi: 10.1111/bju.15068. PMID: 32248617
Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN
World J Urol 2017 Mar;35(3):379-387. Epub 2016 Sep 7 doi: 10.1007/s00345-016-1928-x. PMID: 27604375
Lucca I, Leow JJ, Shariat SF, Chang SL
Hematol Oncol Clin North Am 2015 Apr;29(2):271-88, ix. Epub 2014 Dec 17 doi: 10.1016/j.hoc.2014.10.003. PMID: 25836934

Therapy

Claps F, Pavan N, Ongaro L, Tierno D, Grassi G, Trombetta C, Tulone G, Simonato A, Bartoletti R, Mertens LS, van Rhijn BWG, Mir MC, Scaggiante B
Int J Mol Sci 2023 Aug 9;24(16) doi: 10.3390/ijms241612596. PMID: 37628785Free PMC Article
Liang Y, Tan Y, Guan B, Guo B, Xia M, Li J, Shi Y, Yu Z, Zhang Q, Liu D, Yang X, Hao J, Gong Y, Shakeel M, Zhou L, Ci W, Li X
Theranostics 2022;12(18):7745-7759. Epub 2022 Nov 14 doi: 10.7150/thno.77281. PMID: 36451860Free PMC Article
Li Z, Xu H, Gong Y, Chen W, Zhan Y, Yu L, Sun Y, Li A, He S, Guan B, Wu Y, Xiong G, Fang D, He Y, Tang Q, Yao L, Hu Z, Mei H, He Z, Cai Z, Guo Y, Li X, Zhou L, Huang W
Adv Sci (Weinh) 2022 Feb;9(4):e2103999. Epub 2021 Dec 16 doi: 10.1002/advs.202103999. PMID: 34914855Free PMC Article
Leow JJ, Chong YL, Chang SL, Valderrama BP, Powles T, Bellmunt J
Eur Urol 2021 May;79(5):635-654. Epub 2020 Aug 12 doi: 10.1016/j.eururo.2020.07.003. PMID: 32798146
Birtle A, Johnson M, Chester J, Jones R, Dolling D, Bryan RT, Harris C, Winterbottom A, Blacker A, Catto JWF, Chakraborti P, Donovan JL, Elliott PA, French A, Jagdev S, Jenkins B, Keeley FX Jr, Kockelbergh R, Powles T, Wagstaff J, Wilson C, Todd R, Lewis R, Hall E
Lancet 2020 Apr 18;395(10232):1268-1277. Epub 2020 Mar 5 doi: 10.1016/S0140-6736(20)30415-3. PMID: 32145825Free PMC Article

Prognosis

Qu Y, Yao Z, Xu N, Shi G, Su J, Ye S, Chang K, Li K, Wang Y, Tan S, Pei X, Chen Y, Qin Z, Feng J, Lv J, Zhu J, Ma F, Tang S, Xu W, Tian X, Anwaier A, Tian S, Xu W, Wu X, Zhu S, Zhu Y, Cao D, Sun M, Gan H, Zhao J, Zhang H, Ye D, Ding C
Cell Rep Med 2023 Sep 19;4(9):101166. Epub 2023 Aug 25 doi: 10.1016/j.xcrm.2023.101166. PMID: 37633276Free PMC Article
Lin TW, Yeh HC
Ann Surg Oncol 2022 May;29(5):3318-3319. Epub 2022 Jan 3 doi: 10.1245/s10434-021-11298-y. PMID: 34978673
Lemke E, Sahasrabudhe D, Guancial E, Bylow K, Johnson S, Messing E, Kilari D
Clin Genitourin Cancer 2020 Aug;18(4):e478-e483. Epub 2020 Jan 27 doi: 10.1016/j.clgc.2020.01.003. PMID: 32085986
Miyazaki J, Nishiyama H
Int J Urol 2017 Oct;24(10):730-734. Epub 2017 May 21 doi: 10.1111/iju.13376. PMID: 28543959
Lucca I, Leow JJ, Shariat SF, Chang SL
Hematol Oncol Clin North Am 2015 Apr;29(2):271-88, ix. Epub 2014 Dec 17 doi: 10.1016/j.hoc.2014.10.003. PMID: 25836934

Clinical prediction guides

Qu Y, Yao Z, Xu N, Shi G, Su J, Ye S, Chang K, Li K, Wang Y, Tan S, Pei X, Chen Y, Qin Z, Feng J, Lv J, Zhu J, Ma F, Tang S, Xu W, Tian X, Anwaier A, Tian S, Xu W, Wu X, Zhu S, Zhu Y, Cao D, Sun M, Gan H, Zhao J, Zhang H, Ye D, Ding C
Cell Rep Med 2023 Sep 19;4(9):101166. Epub 2023 Aug 25 doi: 10.1016/j.xcrm.2023.101166. PMID: 37633276Free PMC Article
Wu J, Jin S, Gu C, Wei Y, Zhu Y, Necchi A, Shariat SF, Pan J, Gan H, Dai B, Zhang H, Shi G, Zhu Y, Shen Y, Zhu Y, Ye D
Cell Rep Med 2023 Jan 17;4(1):100883. Epub 2023 Jan 10 doi: 10.1016/j.xcrm.2022.100883. PMID: 36630951Free PMC Article
Liang Y, Tan Y, Guan B, Guo B, Xia M, Li J, Shi Y, Yu Z, Zhang Q, Liu D, Yang X, Hao J, Gong Y, Shakeel M, Zhou L, Ci W, Li X
Theranostics 2022;12(18):7745-7759. Epub 2022 Nov 14 doi: 10.7150/thno.77281. PMID: 36451860Free PMC Article
Tomiyama E, Fujita K, Nakano K, Kuwahara K, Minami T, Kato T, Hatano K, Kawashima A, Uemura M, Takao T, Fushimi H, Katayama K, Imoto S, Yoshimura K, Imamura R, Uemura H, Nonomura N
Curr Oncol 2022 May 30;29(6):3911-3921. doi: 10.3390/curroncol29060312. PMID: 35735421Free PMC Article
Bersanelli M, Mazzaschi G, Giannatempo P, Raggi D, Farè E, Maruzzo M, Basso U, De Giorgi U, Vignani F, Banna GL, Stellato M, Tambaro R, Naglieri E, Losanno T, Procopio G, Pignata S, Necchi A, Buti S
Immunotherapy 2022 Feb;14(2):107-114. Epub 2021 Nov 17 doi: 10.2217/imt-2021-0109. PMID: 34784782

Recent systematic reviews

Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
Soualhi A, Rammant E, George G, Russell B, Enting D, Nair R, Van Hemelrijck M, Bosco C
BMC Urol 2021 Aug 17;21(1):110. doi: 10.1186/s12894-021-00876-7. PMID: 34404373Free PMC Article
Leow JJ, Chong YL, Chang SL, Valderrama BP, Powles T, Bellmunt J
Eur Urol 2021 May;79(5):635-654. Epub 2020 Aug 12 doi: 10.1016/j.eururo.2020.07.003. PMID: 32798146
Veccia A, Antonelli A, Checcucci E, Falagario U, Carrieri G, Guruli G, De Sio M, Simeone C, Porpiglia F, Autorino R
Clin Genitourin Cancer 2020 Feb;18(1):e10-e20. Epub 2019 Oct 16 doi: 10.1016/j.clgc.2019.10.015. PMID: 31704265
Mbeutcha A, Rouprêt M, Kamat AM, Karakiewicz PI, Lawrentschuk N, Novara G, Raman JD, Seitz C, Xylinas E, Shariat SF
World J Urol 2017 Mar;35(3):337-353. Epub 2016 Apr 21 doi: 10.1007/s00345-016-1826-2. PMID: 27101100

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...